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QOL improvement through the pain control by the milk-derived lactoferrin in the animals

Research Project

Project/Area Number 19380177
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Clinical veterinary science
Research InstitutionTottori University

Principal Investigator

TAKEUCHI Takashi  Tottori University, 農学部, 教授 (20216849)

Co-Investigator(Kenkyū-buntansha) HIKASA Yoshiaki  鳥取大学, 農学部, 教授 (30165071)
OKAMOTO Yoshiharu  鳥取大学, 農学部, 教授 (50194410)
SUGIYAMA Akihiko  鳥取大学, 農学部, 助教 (00432609)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000)
Fiscal Year 2009: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2008: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Fiscal Year 2007: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
Keywordsラクトフェリン / 疼痛管理 / ストレス
Research Abstract

Neoplastic or neurological diseases are in a tendency to increase in aged animals. Because a lot of cases that it is difficult for these disorders to completely heal are accompanied with chronically pain, it is failed to be remarkable as for the animal's QOL. In this project, we used lactoferrin which is safety and food origin, to depress chronic inflammation and pain such as the arthritis. Lactoferrin had suppressing effects on neural transmission of the chronic pain and sympathetic hyper activity in stressful condition. Finally, it is suggested that lactoferrin is one of the useful supplements to improve animal's QOL.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (9 results)

All 2009 2008

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (7 results)

  • [Journal Article] Trans-endothelial and trans-epithelial transfer of lactoferrin into the brain through BBB and BCSFB in adult rats2008

    • Author(s)
      Kamemori N, Takeuchi T, Sugiyama A, Miyabayashi M, Kitagawa H, Shimizu H, Ando K, Harada H.
    • Journal Title

      J. Vet. Med. Sci. 70

      Pages: 313-315

    • NAID

      130000447020

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Trans-endothelial and trans-epithelial transfer of lactoferrin into the brain through BBB and BCSFB in adult rats.2008

    • Author(s)
      Kamemori N., et. al.
    • Journal Title

      Journal of Veterinary Medical Science 70

      Pages: 313-315

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 体内寿命延長に伴うPEG化ラクトフェリンの鎮痛増強効果2009

    • Author(s)
      石川まりこ
    • Organizer
      第148回日本獣医学会学術集会
    • Place of Presentation
      とりぎん文化会館(鳥取)
    • Year and Date
      2009-09-26
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] ポリエチレングリコール修飾ラクトフェリンの肝保護作用および肝細胞における取り込みに関する検討2009

    • Author(s)
      杉山晶彦
    • Organizer
      第148回日本獣医学会学術集会
    • Place of Presentation
      とりぎん文化会館(鳥取)
    • Year and Date
      2009-09-26
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 犬の自律神経系に及ぼすラベンダーオイルの影響2009

    • Author(s)
      土岐志保
    • Organizer
      第148回日本獣医学会学術集会
    • Place of Presentation
      とりぎん文化会館(鳥取)
    • Year and Date
      2009-09-26
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 植物由来長期熟成濾過液(HP-1)が中枢神経系に及ぼす効果2009

    • Author(s)
      竹内崇
    • Organizer
      第63回日本栄養・食糧学会大会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2009-05-22
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] PEG化ラクトフェリンによる鎮痛活性増強効果2008

    • Author(s)
      石川まりこ, 杉山晶彦, 佐藤淳, 清水洋彦, ほか
    • Organizer
      第3回ラクトフェリンフオーラム
    • Place of Presentation
      学術総合センター(東京)
    • Year and Date
      2008-11-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] 中枢神経系に対するラクトフェリンの新規作用2008

    • Author(s)
      竹内崇
    • Organizer
      第32回日本鉄バイオ学会
    • Place of Presentation
      ホテルアラスカ(青森)
    • Year and Date
      2008-09-14
    • Related Report
      2009 Final Research Report
  • [Presentation] 中枢神経系に対するラクトフェリンの新規作用2008

    • Author(s)
      竹内 崇
    • Organizer
      第32回日本鉄バイオ学会
    • Place of Presentation
      ホテル アラスカ(青森)
    • Year and Date
      2008-09-14
    • Related Report
      2008 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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