| Budget Amount *help |
¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2009: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2008: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2007: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
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| Research Abstract |
To understand roles of the surface glycans in regulation of fertilizability of animal sperm, we focused on the glycan-rich glycoproteins whose glycan content was more than 90% by weight. The following two new findings were obtained : (1) Glycan-rich flagellar glycoproteins were discovered in pig and sea urchin, and found to regulate sperm motility through controlling the intracellular calcium ions ; (2) Another type of glycan-rich glycoproteins strongly sticking on the sperm surface was found to be originated from seminal plasma. The detachment of the glycoprotein from the surface during capacitation was related with the higher fertilizability of sperm.
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