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Cohort study of asbestos workers with special reference to type, size, and number of exposed fiber.

Research Project

Project/Area Number 19390167
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Hygiene
Research InstitutionTeikyo University

Principal Investigator

YANO Eiji  Teikyo University, 医学部, 教授 (50114690)

Co-Investigator(Kenkyū-buntansha) KOHYAMA Nobuhiko  東洋大学, 経済学部, 教授 (80133643)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2007: ¥10,660,000 (Direct Cost: ¥8,200,000、Indirect Cost: ¥2,460,000)
Keywords発がん / 石綿 / 喫煙 / コホート内症例対照研究 / アンフィーボール / リソタイル / 悪性中皮腫 / 相乗作用 / クリソタイル / アンフィボール / 曝露評価 / 量反応関係 / コホート研究 / 患者対照研究
Research Abstract

By a case-control study within a cohort of an asbestos plant in China, we found 5 times elevation of the incidence of lung cancer among high exposed non-smoking workers but it was 3 times for smokers with low asbestos exposure. However, it elevated to more than10 times when workers smoke and exposed to high level of asbestos suggesting the synergistic effects of the two for lung cancer. In the lung tissue of a male mesothelioma case, chrysotile was seldom found, whereas vast majority was tremolite which scarcely existed in the low material.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (19 results)

All 2009 2008 2007 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (12 results) Remarks (2 results)

  • [Journal Article] Mesothelioma in a worker who spun chrysotile asbestos at home during childhood 2009 Jan 132009

    • Author(s)
      Yano E, Wang ZM, Wang XR, Wang MZ, Takata A, Kohyama N, Suzuki Y.
    • Journal Title

      American Journal of Industrial Medicine 52巻

      Pages: 282-287

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mesothelioma in a worker who spun chrysotile asbestos at home during childhood 2009 Jan 13.2009

    • Author(s)
      Yano E, Wang ZM, Wang XR, Wang MZ, Takata A, Kohyama N, Suzuki Y.
    • Journal Title

      American Journal of Industrial Medicine 52

      Pages: 282-287

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MesotheJioma in a worker who spun chrysotile asbestos at home during Childhood2009

    • Author(s)
      Yano E. Wang ZM, Wang XR, Wang MZ, Takata A, Kohyama N, Suzuki Y
    • Journal Title

      Am J Ind Med. 52

      Pages: 282-287

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mesothelioma in a worker who spun chrysotile asbestos at home during childhood2008

    • Author(s)
      Yano E, Wang ZM, Wang XR, Wang MZ, Takata A, Kohyama N, Suzuki Y
    • Journal Title

      Am J Ind Med. 51(In press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lung cancer mortality from exposure to chrysotile asbestos and smoking: A case-control study within a cohort in China.

    • Author(s)
      Yano E, Wang XR, Wang, MZ, Qiu H, Wang ZM
    • Journal Title

      Occup Environ Med (in press)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Presentation] Industrial hygiene in an asbestos plant with high incidence of lung cancer2009

    • Author(s)
      Yano E, Wang XR, Konishi Y, Yoneyama R, Wang MZ, Wang ZM
    • Organizer
      Collegium Ramazzini 2009
    • Place of Presentation
      Carpi、Italy
    • Year and Date
      2009-10-25
    • Related Report
      2009 Final Research Report
  • [Presentation] Industrial hygiene in an asbestos plant with high incidenceof lung cancer2009

    • Author(s)
      Yano E, Wang XR, Konishi Y, Yoneyama R, Wang MZ, Wang ZM
    • Organizer
      Collegium Ramazzini 2009
    • Place of Presentation
      Carpi、Italy
    • Year and Date
      2009-10-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Cancer mortality by exposure to chrysotile asbestos and smoking: a case-control study within a cohort in China2009

    • Author(s)
      Yano E, Wang XR, H Qui, Wang MZ, Wang ZM
    • Organizer
      International Congress on Occupational Health 2009
    • Place of Presentation
      Cape Town
    • Year and Date
      2009-03-25
    • Related Report
      2009 Final Research Report
  • [Presentation] Cancer mortality by exposure to chrysotile asbestos and smoking : a case-control study within a cohort in China2009

    • Author(s)
      Yano E. Wang XR, H Qui, Wang MZ, Wang ZM
    • Organizer
      Internaiional Congress on Occupational Health 2009
    • Place of Presentation
      Cape Town
    • Year and Date
      2009-03-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] 中国石綿工場の労働衛生管理状況2008

    • Author(s)
      矢野栄二, 小西淑人, 米山玲児, 王暁蓉, 王綿珍, 王治明
    • Organizer
      第17回日本産業衛生学会産業医産業看護全国協議会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-03
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Presentation] Cancer Mortality among chrysotile workers in China-A case-control study within an asbestos plant cohort-2008

    • Author(s)
      Yano E, Wang XR, Wang ZM, Wang MZ, Lan YJ
    • Organizer
      2007 Joint Scientific Meeting of the Australasian Epide miological Association (AGA) and the International Epid emiological Association (IEA) Westen Pacific Region.
    • Place of Presentation
      Hobart(Australia)
    • Year and Date
      2008-08-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] 石綿実践講座専門学術団体としての学会のありかたとリスク管理2008

    • Author(s)
      矢野栄二
    • Place of Presentation
      札幌
    • Year and Date
      2008-06-25
    • Related Report
      2009 Final Research Report
  • [Presentation] 石綿実践講座専門学術団体としての学会のおり方とリスク管理2008

    • Author(s)
      矢野 栄二
    • Organizer
      第81回日本産業衛生学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2008-06-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] Cancer mortality among chrysotile workers 34 years follow up2008

    • Author(s)
      Yano E, Wang XR, Wang ZM, Wang MZ, YJ Lan
    • Place of Presentation
      San Jose (Costa Rica)
    • Year and Date
      2008-06-09
    • Related Report
      2009 Final Research Report
  • [Presentation] Cancer mortality among chrysotile workers 34 years follow up2008

    • Author(s)
      Yano E, Wang XR, Wang ZM, Wang MZ. YJ Lan
    • Organizer
      20th International Conference on Epidemiology in Occupational Health
    • Place of Presentation
      San Jose (Costa Rica)
    • Year and Date
      2008-06-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] Cancer Mortality among chrysotile workers in Chaina-A case-control study within an asbestos plant cohort-2007

    • Author(s)
      Yano E, Wang XR, Wang ZM, Wang MZ, Lan YJ
    • Organizer
      2007 Joint Scientific Meeting of the Australasian Epidemiological Association (AEA) and the International Epid emiological Association (IEA) Western Pacific Region
    • Place of Presentation
      Hobart (Australia)
    • Year and Date
      2007-08-28
    • Related Report
      2009 Final Research Report
  • [Presentation] 石綿問題の最近の動向と日本産業衛生学会の取り組み2007

    • Author(s)
      矢野栄二
    • Organizer
      第80回日本産業衛生学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-04-24
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.teikyo-u.ac.jp/~hph/index.htm

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.med.teikyo-u.ac.jp/~hph/index.htm

    • Related Report
      2009 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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