Pharmacological study to cure mibyo, disease-oriented state
| Project/Area Number |
19390193
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | Sojo University |
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Principal Investigator |
MIYATA Takeshi Sojo University, 薬学部, 教授 (90040310)
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| Co-Investigator(Kenkyū-buntansha) |
ISIHAMA Yoichiro 熊本大学, 大学院・生命科学研究部, 准教授 (10240920)
YOKOMIZO Kazumi 崇城大学, 薬学部, 准教授 (80240919)
HISATSUNE Akinori 熊本大学, 大学院・生命科学研究部, 助教 (50347001)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2009: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2008: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2007: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
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| Keywords | 東洋医学 / 未病 / 抗MUC1抗体 / 抗腫瘍 / グリチルリチン / インターフェロン-γ / 診断マーカー / MUC1 |
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| Research Abstract |
Curing disease-oriented state, very early stage of diseases before they appear, is important to preserve health and prevent illness. In this study, we found that anti-MUC1 antibody, a new anti-cancer biomarker, inhibits cancer cell growth. We also found that glycyrrhizin has glucocorticoid-like anti-inflammatory effect but not through glucocorticoid receptor. These finding may provide a new insight to care disease-oriented state.
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Report
(4 results)
Research Products
(35 results)
