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Clock in the brain : neural substrates of time perception

Research Project

Project/Area Number 19390242
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Neurology
Research InstitutionKyushu University

Principal Investigator

TOBIMATSU Shozo  Kyushu University, 大学院・医学研究院, 教授 (40164008)

Co-Investigator(Kenkyū-buntansha) NAKAJIMA Yoshitaka  九州大学, 大学院・芸術工学研究院, 教授 (90127267)
SHIGETOU Hiroshi  九州大学, 大学病院, 講師 (50335965)
OGATA Katsuya  九州大学, 大学院・医学研究院, 助教 (50380613)
MAEKAWA Toshihiko  九州大学, 大学病院, 助教 (40448436)
齊藤 崇子  九州大学, 大学院・芸術工学研究院, 特別研究員 (70423522)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2009: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2008: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2007: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
Keywords脳の時計 / 時間知覚 / 時間縮小錯覚 / 非侵襲的脳機能計測法 / 神経・精神疾患 / 神経疾患 / 精神疾患
Research Abstract

Time is a fundamental dimension of life. It is now proposed that the brain represents time in a distributed manner and tells the time by detecting the coincidental activation of different neural populations. In this project, we used event-related potentials (ERPs) to explore the mechanisms of auditory and visual temporal assimilation as well as preattentive process. Our preliminary results suggest that right dorsolateral prefrontal cortex plays an important role of temporal assimilation.

Report

(4 results)
  • 2010 Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (65 results)

All 2010 2009 2008 2007 Other

All Journal Article (23 results) (of which Peer Reviewed: 5 results) Presentation (33 results) Book (5 results) Remarks (4 results)

  • [Journal Article] Oscillatory gamma synchronization binds the primary and secondary somatosensory areas in humans.2010

    • Author(s)
      Hagiwara K, Okamoto T, Shigeto H, Ogata K, Somehara Y, Matsushita T, Kira JI, Tobimatsu S
    • Journal Title

      Neuroimage 51

      Pages: 412-420

    • Related Report
      2010 Final Research Report
  • [Journal Article] A Neural Decoding Approach to Auditory Temporal Assimilation2010

    • Author(s)
      Takeichi H, et al
    • Journal Title

      Neural Comput Appl (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ミスマッチ陰性電位とP300を用いた双極性障害の視覚情報自動処理過程の検討2009

    • Author(s)
      角田智哉, 前川敏彦, 織部直弥, 鬼塚俊明, 平野羊嗣, 平野昭吾, 大林長二, 飛松省三, 神庭重信
    • Journal Title

      臨床神経生理学 36

      Pages: 607-614

    • NAID

      10027056076

    • Related Report
      2010 Final Research Report
  • [Journal Article] Electrophysiological evidence of auditory temporal perception related to the assimilation between neighboring two time intervals.2009

    • Author(s)
      Mitsudo T, Nakajima Y, Remijn GB, Takeichi H, Goto Y, Tobimatsu S
    • Journal Title

      NeuroQuantology 7

      Pages: 114-127

    • Related Report
      2010 Final Research Report
  • [Journal Article] Decreased spatial frequency sensitivities for processing faces in male patients with chronic schizophrenia.2009

    • Author(s)
      Obayashi C, Nakashima T, Onitsuka T, Maekawa T, Hirano Y, Hirano S, Oribe N, Kaneko K, Kanba S, Tobimatsu S
    • Journal Title

      Clin Neurophysiol 120

      Pages: 1525-1533

    • Related Report
      2010 Final Research Report
  • [Journal Article] Preattentive visual change detection as reflected by the mismatch negativity (MMN) -evidence for a memory-based process.2009

    • Author(s)
      Maekawa T, Tobimatsu S, Ogata K, Onitsuka T, Kanba S
    • Journal Title

      Neurosci Res 65

      Pages: 107-112

    • NAID

      10027500613

    • Related Report
      2010 Final Research Report
  • [Journal Article] 統合失調症患者と健常者における視覚刺激でのERPの定量解析2009

    • Author(s)
      杉剛直, 後藤和彦, 前川敏彦, 緒方勝也, 後藤純信, 飛松省三, 中村政俊
    • Journal Title

      臨床神経生理学 37

      Pages: 432-440

    • NAID

      10029427937

    • Related Report
      2010 Final Research Report
  • [Journal Article] 視覚刺激のイノベーション2009

    • Author(s)
      後藤純信, 山崎貴男, 飛松省三
    • Journal Title

      臨床脳波 51

      Pages: 713-720

    • Related Report
      2010 Final Research Report
  • [Journal Article] Electrophysiological evidence of auditory temporal perception related to the assimilation between neighboring two time intervals2009

    • Author(s)
      Mitsudo T, et al
    • Journal Title

      NeuroQuantology 7

      Pages: 114-127

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preattentive visual change detection as reflected by the mismatch negativity(MMN)- evidence for a memory-based process.2009

    • Author(s)
      Maekawa T, et al
    • Journal Title

      Neurosci Res 65

      Pages: 107-112

    • NAID

      10027500613

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ミスマッチ陰性電位を用いた統合失調症の視覚情報自動処理過程の検討.2008

    • Author(s)
      前川敏彦, 平野昭吾, 大林長二, 平野羊嗣, 鬼塚俊明, 飛松省三, 神庭重信
    • Journal Title

      臨床脳波 50

      Pages: 202-208

    • Related Report
      2010 Final Research Report
  • [Journal Article] Electrophysiological evidence for sequential discrimination of positive and negative facial expressions.2008

    • Author(s)
      Nakashima T, Goto Y, Abe T, Kaneko K, Saito T, Makinouchi A, Tobimatsu, S
    • Journal Title

      Clin Neurophysiol 119

      Pages: 1803-1811

    • Related Report
      2010 Final Research Report
  • [Journal Article] Tobimatsu S: Early ERP components differentially extract facial features: Evidence for spatial frequency-and-contrast detectors.2008

    • Author(s)
      Nakashima T, Kaneko K, Goto Y, Abe T, Mitsudo T, Ogata K, Makinouchi A
    • Journal Title

      Neurosci Res 62

      Pages: 225-235

    • Related Report
      2010 Final Research Report
  • [Journal Article] 非侵襲的脳機能検査法の進歩と臨床神経生理学2008

    • Author(s)
      飛松省三
    • Journal Title

      福岡医誌 99

      Pages: 7-12

    • Related Report
      2010 Final Research Report
  • [Journal Article] Electrophysiological evidence for sequential discrimination of positive and negative facial expressions2008

    • Author(s)
      Nakashima T, et al
    • Journal Title

      Clin Neurophysiol 119

      Pages: 1808-1811

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Early ERP components differentially extract facial features : Evidence for spatial frequency-and-contrast detectors2008

    • Author(s)
      Nakashima T, et al
    • Journal Title

      Neurosci Res 62

      Pages: 225-235

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 視覚認知に対するボトムアップ的アプローチ2007

    • Author(s)
      飛松省三
    • Journal Title

      認知神経科学 9

      Pages: 182-188

    • NAID

      130004388084

    • Related Report
      2010 Final Research Report
  • [Journal Article] 認知神経科学と人工知能2007

    • Author(s)
      岡本 剛, 飛松 省三
    • Journal Title

      人工知能学会誌 22

      Pages: 195-200

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 視覚認知に対するボトムナップ的アプローチ2007

    • Author(s)
      飛松 省三
    • Journal Title

      認知神経科学 9

      Pages: 182-188

    • Related Report
      2007 Annual Research Report
  • [Journal Article] A Neural Decoding Approach to Auditory Temporal Assimilation.

    • Author(s)
      Takeichi H, Mitsudo T, Nakajima Y, Remijn GB, Goto Y, Tobimatsu S
    • Journal Title

      Neural Comput Appl (in press)

    • Related Report
      2010 Final Research Report
  • [Journal Article] Top-down and bottom-up visual information processing of non-social stimuli in high-functioning autism spectrum disorder.

    • Author(s)
      Maekawa T, Tobimatsu S, Inada N, Oribe N, Onitsuka T, Kanba S, Yoko Kamio Y
    • Journal Title

      Research in Autism Spectrum Disorders. (in press)

    • NAID

      120004951562

    • Related Report
      2010 Final Research Report
  • [Journal Article] Parvocellular pathway impairment in autism spectrum disorder: Evidence from visual evoked potentials.

    • Author(s)
      Fujita T, Yamasaki T, Kamio Y, Hirose S, Tobimatsu S
    • Journal Title

      Research in Autism Spectrum Disorders (in press)

    • Related Report
      2010 Final Research Report
  • [Journal Article] International Federation for Clinical Neurophysiology: Recommendations for Visual System Testing.

    • Author(s)
      Holder GE, Celesia GG, Miyake Y, Tobimatsu S, Weleber RG
    • Journal Title

      Clin Neurophysiol (in press)

    • Related Report
      2010 Final Research Report
  • [Presentation] Visual information processing of face perception.2010

    • Author(s)
      Tobimatsu S
    • Organizer
      Workshop on Microwave Devices, Systems and their Applications
    • Place of Presentation
      KASTEC, Kyushu University
    • Year and Date
      2010-03-16
    • Related Report
      2010 Final Research Report
  • [Presentation] 視覚情報処理: What, Where, When.2010

    • Author(s)
      飛松省三
    • Organizer
      札幌医科大学シンポジウム「脳機能検索法の未来」
    • Place of Presentation
      札幌
    • Year and Date
      2010-02-06
    • Related Report
      2010 Final Research Report
  • [Presentation] Visual gnosis and face perception.2009

    • Author(s)
      Tobimatsu S
    • Organizer
      2009 International Symposium on Early Detection and rehabilitation Technology
    • Place of Presentation
      Okayama, Japan
    • Year and Date
      2009-12-19
    • Related Report
      2010 Final Research Report
  • [Presentation] 多モダリテイー視覚刺激による脳機能推定と臨床応用の現状2009

    • Author(s)
      飛松省三
    • Organizer
      平成21年度統計数理研究所共同利用共同研究集会, 医用診断のための応用統計数理の新展開
    • Year and Date
      2009-12-03
    • Related Report
      2010 Final Research Report
  • [Presentation] Magnetoencephalographic evidence for parallel somatosensory processing in humans.2009

    • Author(s)
      Hagiwara K, Okamoto T, Shigeto H, Somehara Y, Ogata K, Kira J, Tobimatsu S
    • Organizer
      International Society for the Advancement of Clinical Magnetoencephalography (ISACM 2009)
    • Place of Presentation
      Athens, Greece
    • Year and Date
      2009-09-04
    • Related Report
      2010 Final Research Report
  • [Presentation] EEG/MEG exploration on human auditory temporal assimilation.2009

    • Author(s)
      Mitsudo T, Nakajima Y, Remijn GB, Nagaike Y, Goto Y, Tobimatsu S
    • Organizer
      The 18th International Congress on Brain Electromagnetic Topography (ISBET 2009)
    • Place of Presentation
      Kyoto
    • Year and Date
      2009-09-01
    • Related Report
      2010 Final Research Report
  • [Presentation] EEG/MEG exploration on human auditory temporal assimilation2009

    • Author(s)
      Mitsudo T, et al
    • Organizer
      The 18th International Congress on Brain Electromagnetic Topography(ISBET 2009)
    • Place of Presentation
      日本, 京都
    • Year and Date
      2009-09-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] A classifier analysis of electrophysiological evidence of auditory temporal assimilation.2009

    • Author(s)
      Takeichi H, Mitsudo T, Nakajima Y, Remijn GB, Goto Y, Tobimatsu S
    • Organizer
      International Conference of Asia Pacific Psychology (ICAPP 2009)
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-08-25
    • Related Report
      2010 Final Research Report
  • [Presentation] A classifier analysis of electrophysiological evidence of auditory temporal assimilation2009

    • Author(s)
      Takeichi H, et al
    • Organizer
      International Conference of Asia Pacific Psychology(ICAPP 2009)
    • Place of Presentation
      韓国, ソウル
    • Year and Date
      2009-08-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Electrophysiological Substrates of Auditory Temporal Assimilation Between Two Neighboring Time Intervals.2009

    • Author(s)
      Mitsudo T, Nakajima Y, Remijn GB, Takeichi H, Goto Y, Tobimatsu S
    • Organizer
      The Rhythm Perception and Production Workshop (RPPW 2009)
    • Place of Presentation
      Lille, France
    • Year and Date
      2009-07-16
    • Related Report
      2010 Final Research Report
  • [Presentation] Electrophysiological Substrates of Auditory Temporal Assimilation Between Two Neighboring Time Intervals2009

    • Author(s)
      Mitsudo T, et al
    • Organizer
      The Rhythm Perception and Production Workshop(RPPW 2009)
    • Place of Presentation
      フラシス, リール
    • Year and Date
      2009-07-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] Memory trace formation underlies preattentive visual change detection.2009

    • Author(s)
      Maekawa T, Tobimatsu S, Ogata K, T Onitsuka T, S Kanba S
    • Organizer
      Fifth Conference on Mismatch Negativity (MMN) and its Clinical and Scientific Applications.
    • Place of Presentation
      Budapest
    • Year and Date
      2009-04-04
    • Related Report
      2010 Final Research Report
  • [Presentation] An ERP study about altered visual attentional system in bipolar disorder.2009

    • Author(s)
      Maekawa T, Tsunoda T, Oribe N, Fukushima N, Onitsuka T, Tobimatsu S, Kanba S
    • Organizer
      Fifth Conference on Mismatch Negativity (MMN) and its Clinical and Scientific Applications.
    • Place of Presentation
      Budapest
    • Year and Date
      2009-04-04
    • Related Report
      2010 Final Research Report
  • [Presentation] Visual mismatch negativity and P300 to a windmill stimulus in schizophrenia.2009

    • Author(s)
      Maekawa T, Tsunoda T, Fukushima N, Onitsuka T, Tobimatsu S, Kanba S
    • Organizer
      Fifth Conference on Mismatch Negativity (MMN) and its Clinical and Scientific Applications.
    • Place of Presentation
      Budapest
    • Year and Date
      2009-04-04
    • Related Report
      2010 Final Research Report
  • [Presentation] 視覚刺激のイノベーション2008

    • Author(s)
      後藤純信, 山崎貴男, 飛松省三
    • Organizer
      第38回日本臨床神経生理学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-11-14
    • Related Report
      2010 Final Research Report
  • [Presentation] 無意識と意識の中の時間:心理的、電気生理学的アプローチ2008

    • Author(s)
      飛松省三
    • Organizer
      第38回日本臨床神経生理学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-11-13
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] 視覚刺激を用いた「時間知覚の同化現象」に関する研究.2008

    • Author(s)
      長池淳, 光藤崇子, 中島祥好, 緒方勝也, 山崎貴男, 後藤純信, 飛松省三
    • Organizer
      第38回日本臨床神経生理学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-11-13
    • Related Report
      2010 Final Research Report
  • [Presentation] 視覚刺激を用いた「時間知覚の同化現象」に関する研究2008

    • Author(s)
      長池淳, 他
    • Organizer
      第38回日本臨床神経生理学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-11-13
    • Related Report
      2008 Annual Research Report
  • [Presentation] 聴覚における時間的同化現象の脳内メカニズム.2008

    • Author(s)
      光藤崇子, 中島祥好, Gerard Remijn, 後藤純信, 飛松省三
    • Organizer
      第38回日本臨床神経生理学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-11-12
    • Related Report
      2010 Final Research Report
  • [Presentation] A psychophysiological approach to auditory temporal assimilation.2008

    • Author(s)
      Mitsudo T, Nakajima Y, Remijn GB, Goto Y, Tobimatsu S
    • Organizer
      The 10th International Conference on Music Perception and Cognition.
    • Place of Presentation
      Sapporo
    • Year and Date
      2008-08-27
    • Related Report
      2010 Final Research Report
  • [Presentation] 頭を開けずに脳を見る、測る、探る2008

    • Author(s)
      飛松省三
    • Organizer
      JSTイノベーションプラザ福岡 異分野交流セミナー「生体工学研究の最新動向と展望―V」
    • Place of Presentation
      福岡
    • Year and Date
      2008-07-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] 視覚における時間知覚の同化現象2008

    • Author(s)
      長池淳, 光藤崇子, 中島祥好, 緒方勝也, 山崎貴男, 後藤純信, 飛松省三
    • Organizer
      第13回認知神経科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-12
    • Related Report
      2010 Final Research Report
  • [Presentation] 視覚における2つの隣接する時間感覚の知覚について2008

    • Author(s)
      長池淳, 齋藤崇子, 中島祥好, 緒方勝也, 山崎貴男, 飛松省三
    • Organizer
      平成19年度日本生体医工学会九州支部講演会
    • Year and Date
      2008-03-01
    • Related Report
      2010 Final Research Report
  • [Presentation] 視覚における2つの隣接する時間感覚の知覚について2008

    • Author(s)
      長池 淳, 齋藤 崇子, 中島 祥好, 緒方 勝也, 山崎 貴男, 飛松 省三
    • Organizer
      平成19年度日本生体医工学会九州支部講演会
    • Place of Presentation
      福岡
    • Year and Date
      2008-03-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] 脳は騙されない-特にボトムアップ的情報検出について2008

    • Author(s)
      飛松省三
    • Organizer
      第7回京都脳機能研究会
    • Place of Presentation
      京都
    • Year and Date
      2008-02-07
    • Related Report
      2010 Final Research Report
  • [Presentation] Neural correlates of asymmetrical auditory temporal assimilation.2007

    • Author(s)
      Saito T, Nakajima Y, Remijn GB, Goto Y, Tobimatsu S
    • Organizer
      The Second International Symposium on Design of Artificial Environments.
    • Place of Presentation
      Fukuoka
    • Year and Date
      2007-12-01
    • Related Report
      2010 Final Research Report
  • [Presentation] Effects of spatial frequency on recognition of facial expressions: An ERP study.2007

    • Author(s)
      Nakashima T, Yamasaki T, Goto Y, Kaneko K, Tobimatsu S
    • Organizer
      The Second International Symposium on Design of Artificial Environments.
    • Place of Presentation
      Fukuoka
    • Year and Date
      2007-12-01
    • Related Report
      2010 Final Research Report
  • [Presentation] Neural correlates of asymmetrical auditory temporal assimilation2007

    • Author(s)
      Saito T, Nakajima Y, Remijn GB, Goto Y, Tobimatsu S
    • Organizer
      The Second International Symposium on Design of Artificial Environments
    • Place of Presentation
      福岡
    • Year and Date
      2007-12-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] 時間縮小錯覚による聴覚時間知覚機構2007

    • Author(s)
      齋藤崇子, 中島祥好, Remijn Gerard B, 後藤純信, 飛松省三
    • Organizer
      第37回日本臨床神経生理学会学術大会
    • Place of Presentation
      宇都宮
    • Year and Date
      2007-11-22
    • Related Report
      2010 Final Research Report 2007 Annual Research Report
  • [Presentation] 統合失調症における視覚性P300とミスマッチ陰性電位の検討2007

    • Author(s)
      前川俊彦, 角田智哉, 平野羊嗣, 平野昭吾, 大林長二, 吉田猛, 鬼塚俊明, 神庭重信, 飛松省三
    • Organizer
      第37回日本臨床神経生理学会学術大会
    • Place of Presentation
      宇都宮
    • Year and Date
      2007-11-22
    • Related Report
      2010 Final Research Report
  • [Presentation] 視覚認知に対するボトムアップ的アプローチ.2007

    • Author(s)
      飛松省三
    • Organizer
      第12回認知神経科学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2007-07-21
    • Related Report
      2010 Final Research Report
  • [Presentation] Evidence for Visual Analogue of Auditory Mismatch Negativity.2007

    • Author(s)
      Maekawa T, Kanba S, Tobimatsu S
    • Organizer
      2007 IEEE/ICME
    • Place of Presentation
      Beijing
    • Related Report
      2010 Final Research Report
  • [Presentation] Visual ERPs and cortical functions.2007

    • Author(s)
      Tobimatsu S
    • Organizer
      International Workshop on "Event Related Potentials in Patients with Epilepsy
    • Place of Presentation
      Kyoto
    • Related Report
      2010 Final Research Report
  • [Book] EEG/MEG exploration on human auditory temporal assimilation2009

    • Author(s)
      Mitsudo T, Nakajima Y, Remijn GB, Nagaike Y, Goto Y, Tobimatsu S
    • Publisher
      In: Kobayashi T, Ozaki I, Nagata K (eds), Brain Topography and Multimodal Imaging
    • Related Report
      2010 Final Research Report
  • [Book] 認知神経科学と神経学2009

    • Author(s)
      飛松省三
    • Publisher
      呉景龍, 津本周作(編)
    • Related Report
      2010 Final Research Report
  • [Book] 認知神経科学と神経学. 呉景龍, 本周作(編), 神経医工学2009

    • Author(s)
      飛松省三
    • Total Pages
      58
    • Publisher
      オーム社
    • Related Report
      2009 Annual Research Report
  • [Book] Visual ERPs and cortical function.2008

    • Author(s)
      Tobimatsu S, Goto Y, Yamasaki T, Nakashima T, Tomoda Y, Mitsudome A
    • Publisher
      In: Ikeda A, Inoue Y (eds), Progress in epileptic disorders Vol. 5, Event-related potentials in patients with epilepsy: from current state to future prospects
    • Related Report
      2010 Final Research Report
  • [Book] Visual ERPs and cortical function.In : Ikeda A, Inoue Y(eds), Progress in epileptic disorders Vol.5, Event-related potentials in patients with epilepsy : from current state to future prospects2008

    • Author(s)
      Tobimatsu S, et al
    • Total Pages
      291
    • Publisher
      John Libbey Eurotext, Paris.
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://www.med.kyushu-u.ac.jp/neurophy/

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://www.med.kyushu-u.ac.jp/neurophy/

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.kyushu-u.ac.jp/neurophy/

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.kyushu-u.ac.jp/neurophy/

    • Related Report
      2007 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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