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Study of time-functional abnormality in the inside of sensory memory in schizophrenia

Research Project

Project/Area Number 19390299
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Psychiatric science
Research InstitutionFukushima Medical University (2008-2010)
Hirosaki University (2007)

Principal Investigator

YABE Hirooki  福島県立医科大学, 医学部, 准教授 (60210316)

Co-Investigator(Kenkyū-buntansha) KURATA Kiyoshi  弘前大学, 大学院・医学研究科, 教授 (30170070)
MATSUOKA Takashi  福島県立医科大学, 医学部, 併任講師 (30400162)
KANEKO Sunao  弘前大学, 大学院・医学研究科, 教授 (40106852)
NIWA Shin-ichi  福島県立医科大学, 医学部, 教授 (30110703)
Project Period (FY) 2007 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Keywordsミスマッチ陰性電位 / MMN / 感覚記憶 / 統合失調症 / 時間統合窓 / TWI / 聴覚性感覚記憶 / 時間統合機能 / 時間圧縮 / 脳波 / 脳磁図
Research Abstract

Human being has developed automatic defensive mechanism in the acoustic brain to detect the deviated sounds coming from the dangerous events. The sensory memory underlying this mechanism is reflected by the mismatch negativity(MMN) located in the vicinity of the primary auditory cortex. Our previous MMN findings strongly supports that the of preceding sounds is integrated into the sensory memory as a time-wise neural image 160-170ms epoch. The flow of time in the real world may differ from the one in the neural representation of auditory scene stored in the sensory memory, because the neutrally encoded information is free from the rule of actual time.
We found that the impaired MMN in schizophrenia might be caused by the abnormality of time-functional neural trace related to the dysfunction of temporal integration window(TWI) by measuring MMN with special TWI paradigm.(in submission)

Report

(6 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report   Self-evaluation Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (100 results)

All 2011 2010 2009 2008 2007

All Journal Article (25 results) (of which Peer Reviewed: 14 results) Presentation (70 results) Book (5 results)

  • [Journal Article] Temporal integration of deviant sound in automatic detection reflected by mismatch negativity2011

    • Author(s)
      Shiga T, Yabe H., Yu L, Nozaki M, Itagaki S, Lan TH, Niwa S.
    • Journal Title

      Neuroreport

      Volume: 22(7) Pages: 337-41

    • Related Report
      2010 Final Research Report
  • [Journal Article] Thyroid-stimulating hormone elevation misdiagnosed as subclinical hypothyroidism following non-convulsive status epilepticus : a case report2011

    • Author(s)
      Wada A, Suzuki Y, Midorikawa S, Takeuchi S, Kunii Y, Yabe H., Niwa S.
    • Journal Title

      J Med Case Reports

      Volume: 5 Pages: 432-432

    • Related Report
      2010 Final Research Report
  • [Journal Article] Altered DARPP-32 expression in the superior temporal gyrus in schizophrenia2011

    • Author(s)
      Kunii Y, Yabe H., Wada A, Yang Q, Nishiura K, Niwa S.
    • Journal Title

      Prog Neuropsychopharmacol Biol Psychiatry

      Volume: 35(4) Pages: 1139-43

    • Related Report
      2010 Final Research Report
  • [Journal Article] Event-related potentials in patients with adult attention-deficit/hyperactivity disorder versus schizophrenia2011

    • Author(s)
      Itagaki S, Yabe H., Mori Y, Ishikawa H, Takanashi Y, Niwa S.
    • Journal Title

      Psychiatry Res

      Volume: 189(2) Pages: 288-91

    • Related Report
      2010 Final Research Report
  • [Journal Article] Temporal integration of deviant sound in automatic detection reflected by mismatch negativity.2011

    • Author(s)
      Shiga T, Yabe H, Yu L, Nozaki M, Itagaki S, Lan TH, Niwa S.
    • Journal Title

      Neuroreport

      Volume: 22 Pages: 337-341

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ミスマッチ陰性電位(MMN)を用いたパーキンソン病患者における自動的弁別処理機構の検討2010

    • Author(s)
      星野雄哉, 田中秀明, 朝井廉, 矢部博興, 平田幸一
    • Journal Title

      臨床神経生理学

      Volume: 38 Pages: 24-31

    • NAID

      10027056610

    • Related Report
      2010 Final Research Report
  • [Journal Article] 持続長ミスマッチ陰性電位(MMN)の有用性2010

    • Author(s)
      矢部博興、于楽、野崎途也、大島洋和、志賀哲也、沓沢有希子、藤森春生、河野創一、板垣俊太郎、後藤大介、丹羽眞一
    • Journal Title

      臨床脳波

      Volume: 52 Pages: 365-370

    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Journal Article] ミスマッチ陰性電位 (MMN) を用いたパーキンソン病患者における自動的弁別処理機構の検討2010

    • Author(s)
      星野雄哉, 矢部博興, ら
    • Journal Title

      臨床神経生理学 38

      Pages: 24-31

    • NAID

      10027056610

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] 統合失調症における聴覚性MMNの異常2009

    • Author(s)
      松岡貴志、晝間臣治、矢部博興、朝井廉、原悦子、兼子直
    • Journal Title

      臨床脳波

      Volume: 51 Pages: 673-679

    • Related Report
      2010 Final Research Report
  • [Journal Article] 統合失調症と気分障害のNIRS研究2009

    • Author(s)
      矢部博興, 河野創一, 三浦祥恵, 吉田衣美, 境洋二郎, 後藤大介, 丹羽眞一
    • Journal Title

      精神疾患とNIRS III. 精神疾患への応用、中山書店 4(In press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Duration, Frequency, and Intensity Deviants Reveal Different Patterns of Mismatch Negativity Reduction in Early and Late Schizophrenia2008

    • Author(s)
      Todd J., Michie P. T., Schall U., Karayanidis F., Yabe H., and Naatanen R.
    • Journal Title

      Biol Psychiatry

      Volume: 63 Pages: 58-64

    • Related Report
      2010 Final Research Report
  • [Journal Article] Memory trace dependence on number of stimuli in magnetic mismatch negativity2008

    • Author(s)
      Matuoka T., Yabe H., Ren A., Hara E., Kaneko S.
    • Journal Title

      Neuroreport

      Volume: 19 Pages: 1003-1007

    • Related Report
      2010 Final Research Report
  • [Journal Article] The Potential for New Understandings of Normal and Abnormal Cognition by Integration of Neuroimaging and Behavioral Data : Not an Exercise in Carrying Coals to Newcastle2008

    • Author(s)
      Michie P. T., Budd T. W., Fulham W. R., Hughes M. E., Jamadar S., Johnston P., Karayanidis F., Matthews N., Rasser P. E., Schall U. Thompson P. M., Todd J., Ward P. B. and Yabe H.
    • Journal Title

      Brain Imaging and Behavior

      Volume: 2 Pages: 318-326

    • Related Report
      2010 Final Research Report
  • [Journal Article] Deviant Matters : Duration, Frequency, and Intensity Deviants Reveal Different Patterns of Mismatch Negativity Reduction in Early and Late Schizophrenia2008

    • Author(s)
      Todd J., Yabe H., et al.
    • Journal Title

      Biol Psychiatry 63

      Pages: 58-64

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Memory trace dependence on number of stimuli in magnetic mismatch negativity2008

    • Author(s)
      Matuoka T., Yabe H., et al.
    • Journal Title

      Neuroreport 19

      Pages: 1003-1007

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] The Potential for New Understandings of Normal and Abnormal Cognition by Integration of Neuroimaging and Behavioral Data : Not an Exercise in Carrying Coals to Newcastle2008

    • Author(s)
      Michie P.T., Yabe H., et al.
    • Journal Title

      Brain Imaging and Behavior 2

      Pages: 318-326

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] The potential for new understandings of normal and abnormal cognition by integration of neuroimaging and behavioral data : Not an exercise in Carrying Coals to Newcastle2008

    • Author(s)
      Michie PT, Budd TW, Fulham WR, Hughes ME, Jamadar S, Johnston R, Karayanidis F, Matthews N, Rasser PE, Schall U, Thompson PM, ToddJ, Ward PB, Yabe, H
    • Journal Title

      Brain Imaging and Behavior 2

      Pages: 318-326

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Memory trace dependence on number of stimuli in magnetic mismatch negativity2008

    • Author(s)
      Takashi Matuoka, Hirooki Yabe, Tomiharu Hiruma, Asai Ren, Etsuko Hara, Sunao Kaneko
    • Journal Title

      NeuroReport 2

      Pages: 1003-1007

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Deviant Matters : Duration, Frequency, and Intensity Deviants Reveal Different Patterns of Mismatch Negativity Reduction in Early and Late Schizophrenia.2008

    • Author(s)
      Todd J., Michie P. T., Schall U., Karayanidis F., Yabe H., Naatanen R.
    • Journal Title

      Biological Psychiatry 63

      Pages: 58-64

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The potential for new understandings of normal and abnormal cognition by integration of neuroimaging and behavioral: Not an exercise in Carrying Coals to Newcastle2008

    • Author(s)
      Michie PT, Budd TW, Fulham WR, Hughes ME, Jamadar S, Johnston P, Karayanidis F, Matthews N, Rasser PE, Schall U, Thompson PM, Todd J, Ward PB, Yabe, H
    • Journal Title

      Brain Imaging and Behavior (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Memory trace dependence on number of stimuli in magnetic mismatch negativity2008

    • Author(s)
      Takashi Matuoka, Hirooki Yabe, Tomiharu Hiruma, Asai Ren, Etsuko Hara and Sunao Kaneko
    • Journal Title

      NeuroReport (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ミスマッチ陰性電位研究における二つの重要課題2007

    • Author(s)
      矢部博興、松岡貴志、朝井廉、兼子直
    • Journal Title

      臨床脳波

      Volume: 49 Pages: 735-739

    • Related Report
      2010 Final Research Report
  • [Journal Article] ミスマッチ陰性電位研究における二つの重要課題2007

    • Author(s)
      矢部博興, ら
    • Journal Title

      臨床脳波 49

      Pages: 735-739

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Deviant Matters: Duration, Frequency, and Intensity Deviants Reveal Different Patterns of Mismatch Negativity Reduction in Early and Late Schizophrenia.2007

    • Author(s)
      Todd J., Michie P. T., Schall U., Karayanidis F., Yabe H., and Naatanen R.
    • Journal Title

      Biological Psychiatry 63

      Pages: 58-64

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ミスマッチ陰性電位研究における二つの重要課題2007

    • Author(s)
      矢部博興、松岡貴志、朝井廉、兼子直
    • Journal Title

      臨床脳波 49

      Pages: 735-739

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] ヒト大脳新皮質機能研究の最前線:MMNと時間統合機能2011

    • Author(s)
      矢部博興
    • Organizer
      第41回新潟神経学夏季セミナー
    • Place of Presentation
      新潟
    • Related Report
      2010 Final Research Report
  • [Presentation] NIRS during VFT as a diagnostic tool for depression and duration-MMN as a probe for abnormality in schizophrenia2010

    • Author(s)
      Hirooki Yabe
    • Organizer
      International Symposium for Optical Functional Brain Imaging Applications
    • Place of Presentation
      Taichung, Taiwan
    • Year and Date
      2010-12-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 特別講演:脳に保持される170msの音プローブとしてのMMN2010

    • Author(s)
      矢部博興
    • Organizer
      組織的な大学院教育改革推進プログラム講演会
    • Place of Presentation
      西宮
    • Year and Date
      2010-02-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] 特別講演:能動的作業に関連するERPから無意識的認知を反映するMMNへ-臨床応用に適した脳反応を求めて-2010

    • Author(s)
      矢部博興
    • Organizer
      第32回Fmθ研究会
    • Place of Presentation
      大阪
    • Year and Date
      2010-02-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] NIRS during VFT as a diagnostic tool for depression and duration-MMN as a probe for abnormality in schizophrenia. International symposium for optical functional brain brain imaging applications2010

    • Author(s)
      Yabe H
    • Organizer
      Symposium
    • Place of Presentation
      Taichung Taiwan
    • Related Report
      2010 Final Research Report
  • [Presentation] The concept of temporal integration window and its clinical applications2010

    • Author(s)
      Yabe H
    • Organizer
      29th International Congress of Clinical Neurophysiology Symposium
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] 精神科専門医取得のための研修に関わる問題点2010

    • Author(s)
      矢部博興、丹羽眞一
    • Organizer
      福島県立医大附属病院における後期研修プログラム
    • Place of Presentation
      広島
    • Related Report
      2010 Final Research Report
  • [Presentation] 能動的作業に関連するERPから無意識的認知を反映するMMNへ-臨床応用に適した脳反応を求めて-2010

    • Author(s)
      矢部博興
    • Organizer
      第32回Fmθ研究会
    • Place of Presentation
      大阪
    • Related Report
      2010 Final Research Report
  • [Presentation] 脳に保持される170msの音プローブとしてのMMN2010

    • Author(s)
      矢部博興
    • Organizer
      組織的な大学院教育改革推進プログラム講演会
    • Place of Presentation
      西宮
    • Related Report
      2010 Final Research Report
  • [Presentation] Mismatch Negativity研究の可能性について2010

    • Author(s)
      矢部博興
    • Organizer
      第27回日本脳電磁図トポグラフィ研究会
    • Related Report
      2010 Final Research Report
  • [Presentation] 事象関連電位と記憶(特にミスマッチ陰性電位について)2010

    • Author(s)
      矢部博興
    • Organizer
      第40回日本臨床神経生理学会学術大会
    • Related Report
      2010 Final Research Report
  • [Presentation] 聴覚性感覚記憶内の時間統合機能について2010

    • Author(s)
      志賀哲也、于楽、大島洋和、野崎途也、沓澤有希子、河野創一、板垣俊太郎、矢部博興、丹羽眞一
    • Organizer
      第40回日本臨床神経生理学会学術大会
    • Related Report
      2010 Final Research Report
  • [Presentation] 聴覚性感覚記憶内の逸脱検出感度の時間関数の左右差に関する検討2010

    • Author(s)
      野崎途也、于楽、志賀哲也、大島洋和、沓澤有希子、藤森春生、河野創一、板垣俊太郎、矢部博興、丹羽眞一
    • Organizer
      第40回日本臨床神経生理学会学術大会
    • Related Report
      2010 Final Research Report
  • [Presentation] mECTで著明な改善が認められた妄想型統合失調症の一例2010

    • Author(s)
      野崎途也、矢部博興
    • Organizer
      第64回東北精神神経学会総会
    • Related Report
      2010 Final Research Report
  • [Presentation] 入院中の統合失調症患者に対する集団疾患教育の効果の検討2010

    • Author(s)
      松本純弥、矢部博興
    • Organizer
      第64回東北精神神経学会総会
    • Related Report
      2010 Final Research Report
  • [Presentation] 感応性妄想性障害と疑われた統合失調症一例2010

    • Author(s)
      大島洋和、矢部博興
    • Organizer
      第64回東北精神神経学会総会
    • Related Report
      2010 Final Research Report
  • [Presentation] 偽幻覚を認めた分離不安障害の一例2010

    • Author(s)
      樋代真一、矢部博興
    • Organizer
      第64回東北精神神経学会総会
    • Related Report
      2010 Final Research Report
  • [Presentation] 左側頭葉に対する低頻度磁気刺激の効果:MMN研究2010

    • Author(s)
      大島洋和、矢部博興、志賀哲也、于楽、榎本博之、宇川義一、丹羽真一
    • Organizer
      第27回日本脳電磁図トポグラフィ研究会
    • Place of Presentation
      松島
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] MMNに反映される時間窓統合(TWI)の発動に関する研究2010

    • Author(s)
      于楽、矢部博興、志賀哲也、野崎途也、大島洋和、板垣俊太郎
    • Organizer
      第27回日本脳電磁図トポグラフィ研究会
    • Place of Presentation
      松島
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Symposium29 : The concept of temporal integration window and its clinical applications2010

    • Author(s)
      Hirooki Yabe
    • Organizer
      29^<th> International Congress of Clinical Neurophysiology (ICCN2010)
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] レクチャーマラソン2:事象関連電位と記憶2010

    • Author(s)
      矢部博興
    • Organizer
      第40回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸
    • Related Report
      2010 Annual Research Report
  • [Presentation] ランチョンセミナー2:Mismatch Negativity研究の可能性について2010

    • Author(s)
      矢部博興
    • Organizer
      第27回日本脳電磁図トポグラフィ研究会
    • Place of Presentation
      松島
    • Related Report
      2010 Annual Research Report
  • [Presentation] 聴覚性感覚記憶内の時間統合機能について2010

    • Author(s)
      志賀哲也、于楽、大島洋和、野崎途也、沓澤有希子、河野創一、板垣俊太郎、矢部博興、丹羽眞一
    • Organizer
      第40回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸
    • Related Report
      2010 Annual Research Report
  • [Presentation] 聴覚性感覚記憶内の逸脱検出感度の時間関数の左右差に関する検討2010

    • Author(s)
      野崎途也、于楽、志賀哲也、大島洋和、沓澤有希子、藤森春生、河野創一、板垣俊太郎、矢部博興、丹羽眞一
    • Organizer
      第40回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸
    • Related Report
      2010 Annual Research Report
  • [Presentation] Event-related potentials(ERPs) in patients with adult attention-deficit/hyperactivity disorder(Adult AD/HD) in comparison with schizophrenia2009

    • Author(s)
      Itagaki S, Le Y, Nozaki M, Fujimori H, Yabe H, Niwa S.
    • Organizer
      Symposium
    • Place of Presentation
      Kyoto Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] Reduced duration-MMN and impaired temporal integration window in clinical populations2009

    • Author(s)
      Yabe H
    • Organizer
      Special Lecture
    • Place of Presentation
      Budapest Hungary
    • Related Report
      2010 Final Research Report
  • [Presentation] Mismatch Negativity and temporal window of integration2009

    • Author(s)
      Yabe H
    • Organizer
      PhD Program in Biomedicine
    • Place of Presentation
      University of Barcelona
    • Related Report
      2010 Final Research Report
  • [Presentation] 経頭蓋磁気刺激法の歴史と精神医学領域への適用について2009

    • Author(s)
      矢部博興、志賀哲也、板垣俊太郎、國井泰人、河野創一、境洋二郎、和田明、丹羽眞一
    • Organizer
      第31回日本生物学的精神医学会
    • Place of Presentation
      京都
    • Related Report
      2010 Final Research Report
  • [Presentation] 事象関連電位をどう使うか-若手研究者からの提言(6):聴覚MMNの基礎・時間統合機能に関連するduration-MMNの特異性・その臨床応用2009

    • Author(s)
      矢部博興
    • Organizer
      第73回日本心理学会
    • Place of Presentation
      京都
    • Related Report
      2010 Final Research Report
  • [Presentation] 持続長mismatch negativityの臨床応用について2009

    • Author(s)
      板垣俊太郎、野崎途也、于楽、藤森春生、志賀哲也、矢部博興、丹羽眞一
    • Organizer
      第39回日本臨床神経生理学会・学術大会
    • Place of Presentation
      福岡
    • Related Report
      2010 Final Research Report
  • [Presentation] 時間統合窓(TWI)内部における記憶痕跡保存能力の変化について2009

    • Author(s)
      松岡貴志、原悦子、朝井廉、矢部博興、兼子直
    • Organizer
      第39回日本臨床神経生理学会・学術大会
    • Place of Presentation
      福岡市
    • Related Report
      2010 Final Research Report
  • [Presentation] 加齢によるミスマッチ陰性電位(MMN)の変化について2009

    • Author(s)
      原悦子、齊藤慶子、松岡貴志、朝井廉、晝間臣治、矢部博興、保嶋実
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      福岡市
    • Related Report
      2010 Final Research Report
  • [Presentation] Review talks : Reduced duration-MMN and impaired temporal integration window in clinical populations2009

    • Author(s)
      Yabe H.
    • Organizer
      MMN2009
    • Place of Presentation
      Budapest, Hungary
    • Related Report
      2009 Annual Research Report 2009 Self-evaluation Report
  • [Presentation] Symposium 1 : Event-related potentials (ERPs) in patients with adult attention-deficit/hyperactivity disorder (Adult AD/HD) in comparison with schizophrenia2009

    • Author(s)
      Itagaki S., Yabe H., et. al.
    • Organizer
      ISBET2009
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] シンポジウム2:経頭蓋磁気刺激法の歴史と精神医学領域への適用について2009

    • Author(s)
      矢部博興、志賀哲也、板垣俊太郎、國井泰人、河野創一、境洋二郎、和田明、丹羽眞一
    • Organizer
      第31回日本生物学的精神医学会
    • Place of Presentation
      京都
    • Related Report
      2009 Annual Research Report
  • [Presentation] ワークショップ:事象関連電位をどう使うか-若手研究者からの提言(6):聴覚MMNの基礎・時間統合機能に関連するduration-MMNの特異性・その臨床応用2009

    • Author(s)
      矢部博興
    • Organizer
      第73回日本心理学会
    • Place of Presentation
      京都
    • Related Report
      2009 Annual Research Report
  • [Presentation] Symposium 1: Event-related potentials (ERPs) in patients with adult attention-deficit/hyperactivity disorder (Adult AD/HD) in comparison with schizophrenia2009

    • Author(s)
      Shuntaro Itagaki, Yu Le, Michinari Nozaki, Haruo Fujimori, Hirooki Yabe, Shin-ichi Niwa
    • Organizer
      ISBET2009
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] シンポジウム17:持続長mismatch negativityの臨床応用について2009

    • Author(s)
      板垣俊太郎、野崎途也、子楽、藤森春生、志賀哲也、矢部博興、丹羽眞一
    • Organizer
      第39回日本臨床神経生理学会・学術大会
    • Place of Presentation
      福岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] 時間統合窓(TWI)内部における記憶痕跡保存能力の変化について2009

    • Author(s)
      松岡貴志、原悦子、朝井廉、矢部博興、兼子直
    • Organizer
      第39回日本臨床神経生理学会・学術大会
    • Place of Presentation
      福岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] 加齢によるミスマッチ陰性電位(MMN)の変化について2009

    • Author(s)
      原悦子、齊藤慶子、松岡貴志、朝井廉、晝間臣治、矢部博興、保嶋実
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      福岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] Basic researches of mismatch negativity(MMN) and its clinical application2008

    • Author(s)
      Yabe H, Itagaki S, Kasahara S, Sato S, Hidai S, Soda E, Wada A, Kunii K, Niwa S.
    • Organizer
      Symposium
    • Place of Presentation
      Toyama Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] 事象関連電位の基礎と臨床応用、MMNの臨床応用:MMN異常に敏感な持続長MMNと時間統合異常2008

    • Author(s)
      矢部博興
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸
    • Related Report
      2010 Final Research Report
  • [Presentation] 精神医学研修コース4「脳波判読の実際(丹羽眞一):側頭部の脳波所見を高齢者治療に活かす(矢部博興)」2008

    • Author(s)
      矢部博興
    • Organizer
      第104回日本精神神経学会総会
    • Related Report
      2010 Final Research Report
  • [Presentation] 兼子直確率効果における記憶痕跡の発達の影響について(MMN研究)2008

    • Author(s)
      松岡貴志、原悦子、朝井廉、矢部博興
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Final Research Report
  • [Presentation] ミスマッチ陰性電位(MMN)に及ぼす加齢の影響2008

    • Author(s)
      原悦子、齊藤慶子、保嶋実、朝井廉、松岡貴志、矢部博興
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Final Research Report
  • [Presentation] NIRSを用いた、発達障害と若年統合失調症の間の前頭部血液変化量の比較2008

    • Author(s)
      河野創一、三浦祥恵、國井泰人、廣山祐治、矢部博興、丹羽真一
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸市
    • Related Report
      2010 Final Research Report
  • [Presentation] Symposium-23 : Basic researches of mismatch negativity (MMN) and its clinical application2008

    • Author(s)
      Yabe H., et al.
    • Organizer
      2nd WFSBP Asia-Pacific Congress
    • Place of Presentation
      Toyama, Japan
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] Symposium-23 : Basic researches of mismatch negativity (MMN)and its clinical application2008

    • Author(s)
      Hirooki Yabe, Shuntaro Itagaki, Satoshi Kasahara, Kazuaki Sato, Shin-ichi Hidai, Emi Soda, Akira Wada, Yasuto Kunii, Shin-ichi Niwa
    • Organizer
      2nd WFSBP Asia-Pacific Congress
    • Place of Presentation
      富山
    • Related Report
      2008 Annual Research Report
  • [Presentation] シンポジウム16 : 事象関連電位の基礎と臨床応用MMNの臨床応用 : MMN異常に敏感な持続長MMNと時間統合異常2008

    • Author(s)
      矢部博興
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report
  • [Presentation] 確率効果における記憶痕跡の発達の影響について(MMN研究)2008

    • Author(s)
      松岡貴志, 原悦子, 朝井廉, 矢部博興, 兼子直
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report
  • [Presentation] ミスマッチ陰性電位(MMN)に 及ぼす加齢の影響2008

    • Author(s)
      原悦子, 齊藤慶子, 保嶋実, 朝井廉, 松岡貴志, 矢部博興
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report
  • [Presentation] NIRSを用いた、発達障害と若年統合失調症の間の前頭部血液変化量の比較2008

    • Author(s)
      河野創一, 三浦祥恵, 國井泰人, 廣山祐治, 矢部博興, 丹羽真一
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report
  • [Presentation] Time-Functional Information Stored in Auditory Sensory Memory2007

    • Author(s)
      Yabe H, Matsuoka T, Asai R, Iwasa H, and Kaneko S.
    • Organizer
      International Conference on Complex Medical Engineering-CME2007 Symposium
    • Place of Presentation
      Beijing, China
    • Related Report
      2010 Final Research Report
  • [Presentation] Implication of TWI in Clinical Application of MMN2007

    • Author(s)
      Yabe H
    • Organizer
      Event Related Potentials in Patients with Epilepsy(ERPE)
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] Memory-based responseとしてのmismatch negativity2007

    • Author(s)
      矢部博興
    • Organizer
      第22回日本生体磁気学会大会
    • Place of Presentation
      岡崎
    • Related Report
      2010 Final Research Report 2007 Annual Research Report
  • [Presentation] コーディネータ古賀良彦「脳波と脳画像でわかること」2007

    • Author(s)
      矢部博興
    • Organizer
      第103回日本精神神経学会総会
    • Place of Presentation
      大阪
    • Related Report
      2010 Final Research Report
  • [Presentation] ミスマッチ陰性電位(MMN)の経年変化の検討-持続時間の逸脱に関して-2007

    • Author(s)
      原悦子、齊藤慶子、保嶋実、朝井廉、松岡貴志、矢部博興
    • Organizer
      第37回日本臨床神経生理学会・学術大会
    • Place of Presentation
      宇都宮市
    • Related Report
      2010 Final Research Report
  • [Presentation] 逸脱音検出時に誘発される事象関連反応に対する注意の影響2007

    • Author(s)
      朝井廉、矢部博興、原悦子、晝間臣治、松岡貴志、朝井春子、兼子直
    • Organizer
      第37回日本臨床神経生理学会・学術大会
    • Place of Presentation
      宇都宮市
    • Related Report
      2010 Final Research Report
  • [Presentation] 時間統合窓(TWI)内部における逸脱呈示確率の効果について2007

    • Author(s)
      松岡貴志、矢部博興、朝井廉、原悦子、晝間臣治、兼子直
    • Organizer
      第37回日本臨床神経生理学会・学術大会
    • Place of Presentation
      宇都宮市
    • Related Report
      2010 Final Research Report
  • [Presentation] 統合失調症における聴覚性MMNの異常2007

    • Author(s)
      晝間臣治、矢部博興、松岡貴志、朝井廉、兼子直
    • Organizer
      第37回日本臨床神経生理学会・学術大会
    • Place of Presentation
      宇都宮市
    • Related Report
      2010 Final Research Report
  • [Presentation] ミスマッチ陰性電位における時間統合窓機能内部の逸脱検出感度と刺激提示確率との関係について2007

    • Author(s)
      松岡貴志、矢部博興
    • Organizer
      第24回に本脳電磁図トポグラフィ研究会
    • Place of Presentation
      宇都宮市
    • Related Report
      2010 Final Research Report
  • [Presentation] Time-Functional Information Stored in Auditory Sensory Memory. In ; Human Cognitive Function and Complex Signal Technology2007

    • Author(s)
      Yabe H., et al.
    • Organizer
      International Conference on Complex Medical Engineering-CME2007
    • Place of Presentation
      Beijing, China
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] ERPs and Cognitive Dysfunction : Implication of TWI in Clinical Application of MMN.2007

    • Author(s)
      Yabe H.
    • Organizer
      Event Related Potentials in Patients with Epilepsy (ERPE)
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] Time-Functional Information Stored in Auditory Sensory Memory. In; Human Cognitive Function and Complex Signal Technology.2007

    • Author(s)
      Yabe H., Matsuoka T., Asai R., Iwasa H., and Kaneko S.
    • Organizer
      International Conference on Complex Medical Engineering-CME2007
    • Place of Presentation
      北京
    • Related Report
      2007 Annual Research Report
  • [Presentation] ERPs and Cognitive Dysfunction: Implication of TWI in Chinical Application of MMN.2007

    • Author(s)
      Yabe H.
    • Organizer
      Event Related Potentials in Patients with Epilepsy(ERPE)
    • Place of Presentation
      京都
    • Related Report
      2007 Annual Research Report
  • [Presentation] ミスマッチ陰性電位(MMN)の経年変化の検討-持続時間の逸脱に関して-2007

    • Author(s)
      原悦子、齊藤慶子、保嶋実、朝井廉、松岡貴志、矢部博興
    • Organizer
      第37回日本臨床神経生理学会・学術大会
    • Place of Presentation
      宇都宮
    • Related Report
      2007 Annual Research Report
  • [Presentation] 逸脱音検出時に誘発される事象関連反応に対する注意の影響2007

    • Author(s)
      朝井廉、矢部博興、原悦子、晝間臣治、松岡貴志、朝井春子、兼子直
    • Organizer
      第37回日本臨床神経生理学会・学術大会
    • Place of Presentation
      宇都宮
    • Related Report
      2007 Annual Research Report
  • [Presentation] 時間統合窓(TWI)内部における逸脱呈示確率の効果について:第二報2007

    • Author(s)
      松岡貴志、矢部博興、朝井廉、原悦子、晝間臣治、兼子直
    • Organizer
      第37回日本臨床神経生理学会・学術大会
    • Place of Presentation
      宇都宮
    • Related Report
      2007 Annual Research Report
  • [Presentation] 統合失調症における聴覚性MMNの異常2007

    • Author(s)
      晝間臣治、矢部博興、松岡貴志、朝井廉、兼子直
    • Organizer
      第37回日本臨床神経生理学会・学術大会
    • Place of Presentation
      宇都宮
    • Related Report
      2007 Annual Research Report
  • [Presentation] ミスマッチ陰性電位における時間統合窓機能内部の逸脱検出感度と刺激提示確率との関係について2007

    • Author(s)
      松岡貴志、矢部博興
    • Organizer
      第24回に本脳電磁図トポグラフィ研究会
    • Place of Presentation
      神戸
    • Related Report
      2007 Annual Research Report
  • [Book] 現在精神医学事典:ミオクロニーてんかん、発作発射、ポリグラフィー、味覚発作(市川宏伸、鹿島晴雄、加藤敏、狩野力八郎、神庭重信、武田雅俊、中谷陽二編集2011

    • Author(s)
      矢部博興
    • Publisher
      弘文堂
    • Related Report
      2010 Final Research Report
  • [Book] ベッドサイド神経精神医学:神経精神疾患の臨床症状(Ovsiew F.)エッセンシャル神経精神病学と臨床神経科学(Yudofsky S. C. & Hales R.編集),兼子直総監訳2010

    • Author(s)
      矢部博興
    • Publisher
      西村書店
    • Related Report
      2010 Final Research Report
  • [Book] 精神医学における機能的神経画像研究(Patterson J. C. & Taber K. J.)、エッセンシャル神経精神医学と臨床神経科学(Yudofsky S. C. & Hales R.編集),兼子直総監訳2010

    • Author(s)
      阿部由直、矢部博興
    • Publisher
      西村書店
    • Related Report
      2010 Final Research Report
  • [Book] 統合失調症と気分障害のNIRS研究.精神疾患とNIRS III.精神疾患への応用2009

    • Author(s)
      矢部博興、河野創一、三浦祥恵、吉田衣美、境洋二郎、後藤大介、丹羽眞一
    • Publisher
      中山書店
    • Related Report
      2010 Final Research Report
  • [Book] 統合失調症と気分障害のNIRS研究. 精神疾患とNIRS III. 精神疾患への応用2009

    • Author(s)
      矢部博興, ら
    • Publisher
      中山書店
    • Related Report
      2009 Self-evaluation Report

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Published: 2007-04-01   Modified: 2016-04-21  

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