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Repair of peripheral nerve gap by direct lengthening of both stumps

Research Project

Project/Area Number 19390387
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthopaedic surgery
Research InstitutionUniversity of Tsukuba

Principal Investigator

OCHIAI Naoyuki  University of Tsukuba, 大学院・人間総合科学研究科, 教授 (30134563)

Co-Investigator(Kenkyū-buntansha) NISHIURA Yasumasa  筑波大学, 大学院・人間総合科学研究科, 講師 (80208131)
HARA Yuki  筑波大学, 大学院・人間総合科学研究科, 講師 (30431688)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2008: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2007: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
Keywords神経科学 / 再生医学 / 末梢神経伸長 / 整形外科 / カニクイザル / 整形外科学 / Macaca fascicularis / peripheral nerve elongation / segmental nerve defect
Research Abstract

We have developed the new treatment for repair of a segmental nerve gap that simultaneous direct lengthening of both stumps. To determine the applicability of this method to humans, we carried out an experiment on primates. Good results have obtained the primate experiment, we have applied this method clinical setting.
This method does not require the sacrifice of other healthy nerves and nerve regeneration is superior to the present method. We will be able to repair peripheral nerve gap not by nerve grafting but by lengthening the injured nerve itself.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (14 results)

All 2010 2009

All Presentation (14 results)

  • [Presentation] 創外固定器を用いた神経断端直接緩徐伸長による末梢神経欠損部修復法2010

    • Author(s)
      西浦康正, 原友紀, Sharula, Saijilafu, 中島佳子, 落合直之
    • Organizer
      第23回日本創外固定・骨延長学会
    • Place of Presentation
      東京
    • Year and Date
      2010-01-15
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] A new method for peripheral nerve gap repair without nerve grafting-Gradual elongation of both nerve stumps in Macaca fascicularis2009

    • Author(s)
      Ochiai N, Hara Y, Sharula, Saijilafu, Abe I, Nishiura Y.
    • Organizer
      8th APFSSH
    • Place of Presentation
      Kaohsiung (Taiwan)
    • Year and Date
      2009-11-14
    • Related Report
      2009 Final Research Report
  • [Presentation] Repair of 30mm Median nerve Gap by direct lengthening of both nerve stumps in primates2009

    • Author(s)
      Sharula, Hara Y, Nishiura Y, Nakajima Y, Ochiai N
    • Organizer
      8th APFSSH
    • Place of Presentation
      Kaohsiung(Taiwan)
    • Year and Date
      2009-11-13
    • Related Report
      2009 Final Research Report
  • [Presentation] Repair of 30mm Median nerve Gap by direct lengthening of both nerve stumps in primates2009

    • Author(s)
      莎茹拉, 原友紀, 西浦康正, Saijilafu, Kubota S, 落合直之
    • Organizer
      8^<th> Asian Pacific Federation of Societies for Surgery of Hand
    • Place of Presentation
      Taiwan
    • Year and Date
      2009-11-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] 末梢神経緩徐伸長法による神経欠損間隙修復 霊長類における正中神経20mm欠損の治療成績2009

    • Author(s)
      原友紀, 西浦康正, Sharula, 中島佳子, 落合直之
    • Organizer
      第24回日本整形外科学会基礎学術集会
    • Place of Presentation
      神奈川
    • Year and Date
      2009-11-06
    • Related Report
      2009 Final Research Report
  • [Presentation] 末梢神経緩徐伸長法による神経欠損間隙修復 霊長類における正中神経20mm欠損の治療成績2009

    • Author(s)
      原友紀、西浦康正、莎茹拉, 中島佳子, 落合直之
    • Organizer
      日本整形外科学会基礎学術集会
    • Place of Presentation
      神奈川
    • Year and Date
      2009-11-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] 末梢神経緩徐伸長による神経欠損部修復法の研究2009

    • Author(s)
      莎茹拉, 原友紀, 西浦康正, 中島佳子, 久保田茂希, 落合直之
    • Organizer
      東日本整形災害外科学会
    • Place of Presentation
      北海道
    • Year and Date
      2009-09-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] 末梢神経緩徐伸長法による神経欠損間隙修復 : 実験霊長類における治療成績2009

    • Author(s)
      原友紀, 西浦康正, Sharula, 中島佳子, 落合直之
    • Organizer
      第82回日本整形外科学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2009-05-13
    • Related Report
      2009 Final Research Report
  • [Presentation] 末梢神経緩徐伸長法による神経欠損間隙修復 : 実験霊長類における治療成績2009

    • Author(s)
      原友紀, 西浦康正, Sharula, 中島佳子, 落合直之
    • Organizer
      第52回日本手の外科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-17
    • Related Report
      2009 Final Research Report
  • [Presentation] 末梢神経緩徐伸長法による神経欠損間隙修復:実験霊長類における治療成績2009

    • Author(s)
      原友紀、西浦康正、莎茹拉, 中島佳子、落合直之
    • Organizer
      第52回日本手の外科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] 末梢神経再生の基礎と臨床応用神経断端直接緩徐伸長による末梢神経欠損部修復法の研究2009

    • Author(s)
      西浦康正, 賽吉拉夫, 原友紀, 莎茹拉, 落合直之
    • Organizer
      第52回日本手の外科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-16
    • Related Report
      2009 Final Research Report
  • [Presentation] 末梢神経再生の基礎と臨床応用 神経断端直接緩徐伸長による末梢神経欠損部修復法の研究2009

    • Author(s)
      西浦康正, 賽吉拉夫, 原友紀, 莎茹拉, 落合直之
    • Organizer
      第52回日本手の外科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] Repair of peripheral nerve gap by direct lengthening of both nerve stumps in primates2009

    • Author(s)
      Yuki Hara
    • Organizer
      55th Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      Las Vegas
    • Year and Date
      2009-02-23
    • Related Report
      2008 Annual Research Report
  • [Presentation] Repair of peripheral nerve gap by direct lengthening of both stumps in primates2009

    • Author(s)
      Y. Hara, Y. Nishiura, Saijilafu, Sharula, N. Nakajima, Y. Mishima, H. Ono, N. Ochiai
    • Organizer
      55^<th> Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      Las Vegas (USA)
    • Year and Date
      2009-02-22
    • Related Report
      2009 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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