Transplantation of neural crest stem cells for spinal cord injury

• Project/Area Number: 19390400
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Orthopaedic surgery
• Research Institution: Keio University
• Principal Investigator: NAKAMURA Masaya Keio University, 医学部, 講師 (30217898)
• Co-Investigator(Kenkyū-buntansha): TOYAMA Yoshiaki 慶應義塾大学, 医学部, 教授 (40129549) ; ISHII Ken 慶應義塾大学, 医学部, 助教 (00276289)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000); Fiscal Year 2008: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000); Fiscal Year 2007: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
• Keywords: 脊髄損傷 / 神経堤幹細胞 / 再生 / 移植

Research Abstract

本研究により、神経堤幹細胞は成体に至るまで胚葉を超えて各組織に潜伏しており、骨髄等において胚葉転換と表現されている組織幹細胞の多くが実は神経堤由来である可能性が示唆された。臨床応用を考えた場合、神経堤幹細胞は患者の組織から採取することが可能であり、倫理的問題や免疫拒絶反応を回避でき、さらに正常組織から回収するため腫瘍化の可能性も低く、脊髄損傷に対する自家細胞移植の新しい細胞供給源として有用と考えられる。

Research Products

• [Journal Article] Physiological signinficance of astrogliosis after CNS injury (2009)
  • Author(s): Okada S, Nakamura M, et al
  • Journal Title: Inflammation and Regeneration 29 Pages: 35-39
  • Peer Reviewed
• [Journal Article] マンガン神経トレージンク(MRMRI)による霊長類視覚伝導路の描出と網膜神経分布の解析 (2009)
  • Author(s): 山田雅之, 疋島啓吾, 藤吉兼浩, 中村雅也, 岡野栄之, 玉置憲一
  • Journal Title: 日本磁気共鳴医学会雑誌 29 Pages: 23-29
  • Peer Reviewed
• [Journal Article] 高分解能High b-value多軸拡散計測による視交叉神経走行追跡 (2009)
  • Author(s): 疋島啓吾, 山田雅之, 藤吉兼浩, 中村雅也, 玉置憲一, 岡野栄之
  • Journal Title: 日本磁気共鳴医学会雑誌 27 Pages: 41-44
  • NAID: 10026287417
  • Peer Reviewed
• [Journal Article] 実験動物としてのコモンマーモセットと脊髄損傷モデル (2009)
  • Author(s): 北村和也, 藤吉兼浩, 中村雅也, 戸山芳昭, 岡野栄之
  • Journal Title: 分子細胞治療 8 Pages: 145-150
  • Peer Reviewed
• [Journal Article] Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad (2008)
  • Author(s): Nagoshi N, Shibata S, Kubota Y, Nakamura M, Nagai Y, Satoh E, Morikawa S, Okada Y, Mabuchi Y, Katoh H, Okada S, Fukuda K, Suda T, Matsuzaki Y, Toyama Y, Okano H
  • Journal Title: Cell Stem Cell 2 Pages: 392-403
  • Peer Reviewed
• [Journal Article] 進みつづける細胞移植治療の実際 再生医療の実現に向けた科学・技術と周辺要素の理解 細胞移植治療の現状とその周辺環境 (2008)
  • Author(s): 名越慈人, 中村雅也, 岡野栄之
  • Journal Title: 治療を目的とした細胞移植 前駆細胞、組織幹細胞損傷脊髄に対する細胞移植研究遺伝子医学 MOOK Pages: 57-62
• [Journal Article] Multipotent Neural Crest-Derived Stem Cells in Bone Marrow, Dorsal Root Ganglia and Facial Skin. (2008)
  • Author(s): Nagoshi N, Shibata S, Kubota Y, Nakamura M, et al.
  • Journal Title: Cell Stem cell 2 Pages: 392-403
  • Peer Reviewed
• [Journal Article] Spinal cord injury : Emerging beneficial role of reactive astrocytes' migration. Review. (2008)
  • Author(s): Renault-Mihara, F., Nakamura, M., Toyama, Y, & Okano, H.
  • Journal Title: The International Journal of Biochemistry & Cell Biology 9 Pages: 1649-1653
  • Peer Reviewed
• [Journal Article] Diffusion-Tensor Neuronal Fiber Tractography and Manganese-enhanced MR Imaging of Primate Visual Pathway in the Common Marmoset (2008)
  • Author(s): Yamada M, Nakamura M, Aoki S, Tamaoki N, Okano H.
  • Journal Title: Preliminary Results, Radiology 249 Pages: 855-864
  • Peer Reviewed
• [Journal Article] Visualization of peripheral nerve degeneration and regeneration (2008)
  • Author(s): Takagi T, Nakamura M, et al.
  • Journal Title: Neurolmage 44 Pages: 884-892
  • Peer Reviewed
• [Journal Article] The role of cytokine signaling in pathophysiology for spinal cord injury (2008)
  • Author(s): Okada S, Nakamra M, et al.
  • Journal Title: Inflammation and Regeneration 28 Pages: 440-446
  • Peer Reviewed
• [Journal Article] 神経堤幹細胞を用いた移植研究〜神経再生を目指して〜 (2008)
  • Author(s): 名越慈人, 中村雅也, 岡野栄之, 戸山芳昭
  • Journal Title: 臨床整形 43 Pages: 688-691
  • Peer Reviewed
• [Journal Article] Multipotent Neural Crest-Derived Stem Cells in Bone Marrow,Dorsal Root Ganglia and Facial Skin. (2008)
  • Author(s): Nagoshi N. Shibata S, Kubota Y, Nakamura M., et. al.
  • Journal Title: Cell Stem cell 2 Pages: 392-403
  • Peer Reviewed
• [Journal Article] Isolation and characterization of dendritic cells from common marmosets for preclinical studies on cell therapy. (2008)
  • Author(s): Ohta S, Ueda Y, Yaguchi M, Matuszaki Y, Nakamura M., et. al.
  • Journal Title: Immunology 123 Pages: 566-574
  • Peer Reviewed
• [Journal Article] Hepatocyte growth factor promotes endogenous repair and functional recoverv after spinal cord injury. (2007)
  • Author(s): Kitamura K, Iwanami A, Nakamura M., et. al.
  • Journal Title: J Neursci Res 85 Pages: 2332-2342
  • Peer Reviewed
• [Journal Article] ln vivo tracing of neural tracts in the intact and injured strinal cord of marmosets by diffusion tensor tractography. (2007)
  • Author(s): Fujiyoshi K, Yamada M, Nakamura M, et. al.
  • Journal Title: J Neurosci 27 Pages: 11991-11998
  • Peer Reviewed
• [Journal Article] Establishment of Three-dimensional culture of neural stem/progenitor cells in collagen type-1 gel. (2007)
  • Author(s): Watanabe K, Nakamura M, et. al.
  • Journal Title: Rest Neurol Neurosci 25 Pages: 109-117
  • Peer Reviewed
• [Journal Article] Plasma as a scaffold for regeneration of neural precursor cells after transplantation into rats with spinal cord injury. (2007)
  • Author(s): Takenaga M, Ohta Y, Tokura Y, Hamaguchi A, Suzuki N, Nakamura M, et. al.
  • Journal Title: Cell Transplant 16 Pages: 57-65
  • Peer Reviewed
• [Journal Article] Electrical stimulation modulates fate determination of differentiating embryonic stem cells. (2007)
  • Author(s): Yamada M, Tanemura K, Okada S, Iwanami A, Nakamura M, et. al.
  • Journal Title: Stem Cells 25 Pages: 562-570
  • Peer Reviewed
• [Presentation] マウス脂肪組織由来adipoclusterと胎児脳由来神経幹細胞とのキメラ培養 (2009)
  • Author(s): 長瀬敬 岡野栄之 中村雅也 峰松健夫 藤田裕子 村瀬祥子
  • Organizer: 第8回日本再生医療学会
  • Place of Presentation: 東京
  • Year and Date: 2009-03-06
• [Presentation] マウス脂肪組織由来adipoclusterの脊髄初代培養系へのin vitro移植実験 (2009)
  • Author(s): 長瀬敬 岡野栄之 中村雅也 峰松健夫 藤田裕子 村瀬祥子
  • Organizer: 第8回日本再生医療学会
  • Place of Presentation: 東京
  • Year and Date: 2009-03-06
• [Presentation] 骨髄由来神経堤幹細胞の発生と多様性 (2009)
  • Author(s): 名越慈人、芝田晋介、中村雅也、松崎有未、戸山芳昭、岡野栄之
  • Organizer: 第8回日本再生医療学会
  • Place of Presentation: 東京
  • Year and Date: 2009-03-05
• [Presentation] 拡散テンソルトラクトグラフィーによる損傷末梢神経の描出 (2009)
  • Author(s): 高木岳彦, 中村雅也, 岡野James洋尚, 戸山芳昭, 岡野栄之
  • Organizer: 第8回日本再生医療学会
  • Place of Presentation: 東京
  • Year and Date: 2009-03-05
• [Presentation] rhHGFは霊長類脊髄損傷後の上肢運動機能回復を促進する : コモンマーモセットを用いた前臨床試験 (2009)
  • Author(s): 北村和也, 藤吉兼浩, 山中村敏一, 戸山芳昭, 中村雅也, 岡野栄之
  • Organizer: 第8回日本再生医療学会
  • Place of Presentation: 東京
  • Year and Date: 2009-03-05
• [Presentation] 脊髄損傷に対するiPS細胞由来神経幹細胞移植の検討 (2009)
  • Author(s): 辻収彦, 三浦恭子, 中村雅也, 山中仲弥, 岡野栄之
  • Organizer: 第5回宮崎サイエンスキャンプ
  • Place of Presentation: 宮崎
  • Year and Date: 2009-02-10
• [Presentation] Intrathecal administration of recombinant human hepatocyte growth fact or promotes recovery of hand dexterity after cervical spinal cord injury in primate : Preclinical trial using common marmoset (2009)
  • Author(s): Kitamura K, Fujiyoshi K, Nakamura M, et al.
  • Organizer: 55th Annual Meeting of the Orthopaedic Research Society (ORS)
  • Place of Presentation: Las. Vegas, Nevada-USA
• [Presentation] Characterization of neural crest stem cells as the source oftransplantation for spinal cord injury (2008)
  • Author(s): Nagoshi N, Nakamura N, Shibata S, Kugamai G, Matsuzaki Y, Okano H, Toyama Y
  • Organizer: Cervical Spine Research Society
  • Place of Presentation: Austin, USA
  • Year and Date: 2008-12-05
• [Presentation] Characterization of neural crest stem cells as the source oftransplant ation for spinal cord injury (2008)
  • Author(s): Nagoshi N, Nakamura N, et al
  • Organizer: Cervical Spine Research Society
  • Place of Presentation: Austin, USA
  • Year and Date: 2008-12-05
• [Presentation] マウス損傷脊髄に対する神経堤幹細胞移植の検討 (2008)
  • Author(s): 名越慈人, 芝田晋介, 熊谷玄太郎, 松崎有未, 岡野栄之, 戸山芳昭, 中村雅也
  • Organizer: 日本整形外科学会基礎学術集会
  • Place of Presentation: 京都
  • Year and Date: 2008-10-23
• [Presentation] 拡散テンソルMRIの新たな末梢神経画像検査法としての有用性 (2008)
  • Author(s): 高木岳彦, 藤吉兼浩, 岡野J洋尚, 岡野栄之, 戸山芳昭, 中村雅也
  • Organizer: 第23回日本整形外科学会基礎学術集会
  • Place of Presentation: 京都
  • Year and Date: 2008-10-23
• [Presentation] 脊髄損傷に対する人工多能性幹細胞由来神経幹細胞移植の検討 (2008)
  • Author(s): 辻収彦, 三浦恭子, 山中伸弥, 岡野栄之, 戸山芳昭, 中村雅也
  • Organizer: 第23回日本整形外科学会基礎学術集会
  • Place of Presentation: 京都
  • Year and Date: 2008-10-23
• [Presentation] マウス脊髄損傷に対するヒトES細胞由来神経幹細胞の有効性の検討脊髄損傷に対する神経幹細胞移植における至適投与方法の検討 (2008)
  • Author(s): 高橋勇一朗 中村雅也 岡田洋平熊谷玄太郎 岡野栄之 戸山芳昭
  • Organizer: 第23回日本整形外科学会基礎学術集会
  • Place of Presentation: 京都
  • Year and Date: 2008-10-23
• [Presentation] Hepatocyte growth factor (HGF)は脊髄損傷後反応性アストロサイトの遊走を促進する (2008)
  • Author(s): 北村和也, 中村雅也, 船越洋, 中村敏一, 岡野栄之, 戸山芳昭
  • Organizer: 第23回日本整形外科学会基礎学術集会
  • Place of Presentation: 京都
  • Year and Date: 2008-10-23
• [Presentation] 脊髄損傷に対するrecombinant human Hepatocyte Growth Factor (rhHGF)の有効性の検討 (2008)
  • Author(s): 北村和也, 中村雅也, 船越洋, 中村敏一, 岡野栄之, 戸山芳昭
  • Organizer: 第23回日本整形外科学会基礎学術集会
  • Place of Presentation: 京都
  • Year and Date: 2008-10-23
• [Presentation] Establishment of the In vivo Tracing of Spinal Pathway using Diffusion Tensor Imaging (2008)
  • Author(s): Fujiyoshi K, Nakamura M, et al
  • Organizer: International Society for Magnetic Resonance in Medicine 16th Scientific Meeting & Exhibition
  • Place of Presentation: Toronto Canada
  • Year and Date: 2008-05-03
• [Presentation] Diffusion Tensor Tractography of Primate Visual Pathway (2008)
  • Author(s): Yamada M, Nakamura M, Aoki S, Tamaoki N, Okano H, et al
  • Organizer: International Society for Magnetic Resonance in Medicine 16th Scientific Meeting & Exhibition
  • Place of Presentation: Toronto Canada
  • Year and Date: 2008-05-03
• [Presentation] Diffusion Tensor Nerve Tractography (2008)
  • Author(s): Takagi T, Nakamura M, et al.
  • Organizer: International Society for Magnetic Resonance in Medicine 16th Scientific Meeting & Exhibition
  • Place of Presentation: Toronto Canada
  • Year and Date: 2008-05-03
• [Presentation] In vivo high Resolution q-space imaging of the spinal cord injury in Nonhuman primates (2008)
  • Author(s): Hikishima K, Nakamura M, et al.
  • Organizer: International Society for Magnetic Resonance in Medicine 16th Scientific Meeting & Exhibition
  • Place of Presentation: Toronto Canada
  • Year and Date: 2008-05-03
• [Presentation] Diffusion tensor peripheral nerve tractography-Histlogical Changes & Diffusion Anisotropy- (2008)
  • Author(s): Takagi T, Nakamura M, et al.
  • Organizer: International Society for Magnetic Resonance in Medicine 16th Scientific Meeting & Exhibition
  • Place of Presentation: Toronto Canada
  • Year and Date: 2008-05-03
• [Presentation] マウス脊髄圧挫損傷モデルに対する神経堤幹細胞移植の有効性の検討 (2008)
  • Author(s): 名越慈人, 中村雅也, 芝田晋介, 熊谷玄太郎, 松崎有未, 岡野栄之, 戸山芳昭
  • Organizer: 日本脊椎脊髄病学会
  • Place of Presentation: 東京
  • Year and Date: 2008-04-23
• [Presentation] 脊髄損傷に対する神経幹細胞移植における至適投与方法の検討 (2008)
  • Author(s): 高橋勇一朗, 辻収彦, 中村雅也, 他
  • Organizer: 第38回日本脊椎脊髄病学会
  • Place of Presentation: 東京
  • Year and Date: 2008-04-23
• [Presentation] recombinant human Hepatocyte Growth Factorは霊長類脊髄損傷後の上肢運動機能回復を促進する : コモンマーモセットを用いた前臨床試験 (2008)
  • Author(s): 北村和也, 藤吉兼浩, 中村雅也, 他
  • Organizer: 第38回日本脊椎脊髄病学会
  • Place of Presentation: 東京
  • Year and Date: 2008-04-23
• [Presentation] Ontogeny and multipotency of neural crest-derived stem cells in mousebone marrow (2008)
  • Author(s): Nagoshi N, Shibata S, Nakamura N,Matsuzaki Y, Toyama Y, Okano H
  • Organizer: The 6th International Society for Stem Cell Research
  • Place of Presentation: Philadelphia
• [Presentation] Isolation and characterization of neural crest stem cells in adult rodents (2008)
  • Author(s): Nagoshi N, Shibata S, Nakamura M, Matsuzaki Y, Toyama Y, Okano H
  • Organizer: 54^<th> ORS annual meeting
  • Place of Presentation: San Francisco, CA
• [Presentation] Characterization of neural crest stem cells as the source of transplantation for spinal cord injury (2008)
  • Author(s): Nagoshi N, Nakamura N, Shibata S, Kugamai G, Matsuzaki Y, Toyama Y, Okano H
  • Organizer: Society for Neuroscience2008
  • Place of Presentation: Washington, USA
• [Presentation] Ontogeny and multipotency of neural crest-derived stem cells in mouseb one marrow (2008)
  • Author(s): Nagoshi N, Shibata S, Nakamura M, et al.
  • Organizer: The 6th International Society for Stem Cell Research
  • Place of Presentation: Philadelphia
• [Presentation] Diffusion tensor tractography of peripheral nerves-for visualizing nerve fibers- (2008)
  • Author(s): Takagi T, Nakamura M, Yamada M, Fujiyoshi K, Okano H, Toyama Y
  • Organizer: 63rd Annual Meeting of the American Society for Surgery of the Hand
  • Place of Presentation: Chicago, USA
• [Presentation] Intrathecal administration of recombinant human hepatocyte growth factor promotes functional recovery after spinal cord injury ; pre-clinicaltrial using common marmoset (2008)
  • Author(s): Kitamura K, Fujiyoshi K, Nakamura M, et al.
  • Organizer: Neuroscience 2008
  • Place of Presentation: Washington D. C., USA
• [Presentation] Characterization of neural crest stem cells as the source oftransplantation (2008)
  • Author(s): Nagoshi N, Nakamura N, et al.
  • Organizer: Neuroscience 2008
  • Place of Presentation: Washington D, C., USA
• [Presentation] Cell therapy for spinal cord injury by neural stem/progenitor cells derived from induced pluripotent stem cells (2008)
  • Author(s): Osahiko Tsuji, kyoko Miura, Masaya Nakamura, et al.
  • Organizer: Neuroscience 2008
  • Place of Presentation: Washington D. C., USA
• [Presentation] 脊髄損傷に於ける反応性アストロクリアの新しい役割 (2008)
  • Author(s): 岡田誠司, 中村雅也, 岡野栄之, 戸山芳昭, 岩本幸英
  • Organizer: 第81回日本整形外科学術集会
  • Place of Presentation: 札幌
• [Presentation] Comparison between ES cell-derived neurogenic and gliogenic neurospher es as asource of cell transplantation therapy for spinal cord injury (2008)
  • Author(s): 熊谷玄太郎, 中村雅也, 辻収彦, 藤哲, 戸山芳昭, 岡野栄之, 他
  • Organizer: 第81回日本整形外科学術集会
  • Place of Presentation: 札幌
• [Presentation] 末梢神経における拡散テンソルトラクトグラフィー (2008)
  • Author(s): 高木岳彦, 中村雅也, 戸山芳昭, 岡野栄之, 他
  • Organizer: 第31回日本神経科学会
  • Place of Presentation: 東京
• [Presentation] q-space MRI のコモンマーモセット脊髄への適用 (2008)
  • Author(s): 疋島啓吾, 中村雅也, 戸山芳昭, 岡野栄之, 他
  • Organizer: 第31回日本神経科学会
  • Place of Presentation: 東京
• [Presentation] 霊長類脊髄損傷における拡散テンソルトラクトグラフィーを用いたin vivo imaging (2008)
  • Author(s): 藤吉兼浩, 中村雅也, 戸山芳昭, 岡野栄之, 他
  • Organizer: 第31回日本神経科学会
  • Place of Presentation: 東京
• [Presentation] Hepatocyte Growth Factorは損傷脊髄の内在性修復および運動機能回復を促進する : げつ歯類から霊長類へ臨床応用へ向けて (2008)
  • Author(s): 北村和也, 中村雅也, 戸山芳昭, 岡野栄之, 他
  • Organizer: 第31回日本神経科学会
  • Place of Presentation: 東京
• [Presentation] Mechanisms of reactive astrocytes migration after spinal cord injury (2008)
  • Author(s): Renault-Mihara F, Mukaino M, Nakamura M, Toyanma Y, Okano H
  • Organizer: 第31回日本神経科学会
  • Place of Presentation: 東京
• [Presentation] Cell therapy for spinal cord injury by neural stem/progenitor cells derived from induced pluripotent stem cells (2008)
  • Author(s): Osahiko Tsuji, Kyoko Miura, Masaya Nakamura, et al
  • Organizer: 第31回日本神経科学会
  • Place of Presentation: 東京
• [Presentation] Comparison between ES cell-derived neurogenic and gliogenic neurospheres as a source of transplantation for spinal cord injury (2008)
  • Author(s): Kumagai G, Nakamura M, Toyama Y, Okano H, et al.
  • Organizer: 第31回日本神経科学会
  • Place of Presentation: 東京
• [Presentation] 脊髄損傷に対する神経幹細胞移植における至適細胞投与方法の検討 (2008)
  • Author(s): 高橋勇一朗 中村雅也 辻収彦戸山芳昭 岡野栄之, 他
  • Organizer: 第31回日本神経科学会
  • Place of Presentation: 東京
• [Presentation] 制限拡散を利用した脊髄損傷の経時的解析 (2008)
  • Author(s): 藤吉兼浩, 疋島啓吾, 岡野栄之, 戸山芳昭, 中村雅也
  • Organizer: 第36回日本磁気共鳴医学会大会
  • Place of Presentation: 旭川
• [Presentation] マンガン神経トレージンク(MRMRI)による霊長類視覚伝導路の描出と網膜神経分布の解析 (2008)
  • Author(s): 山田雅之, 疋島啓吾, 藤吉兼浩, 中村雅也, 岡野栄之, 玉置憲一
  • Organizer: 第36回日本磁気共鳴医学会大会
  • Place of Presentation: 旭川
• [Presentation] Mechanisms of reactive astrocytes migration after spinal cord injury (2008)
  • Author(s): Renault-Mihara F, Nakamura M, Toyama Y, Okano H
  • Organizer: 第23回内藤コンファレンス
  • Place of Presentation: 湘南
• [Presentation] 高空間・高角度分解能拡散計測による視交叉神経走行の解析 (2008)
  • Author(s): 疋島啓吾, 中村雅也, 玉置憲一, 岡野栄之
  • Organizer: 第36回日本磁気共鳴医学会大会
  • Place of Presentation: 旭川
• [Presentation] Cell therapy for spinal cord injury by neural stem/progenitor cells derived from induced pluripotent stem cells (2008)
  • Author(s): Osahiko Tsuji, Masaya Nakaniura, Shinya Yamanaka, Hideyuki Okano
  • Organizer: 第23回内藤コンファレンス
  • Place of Presentation: 湘南
• [Presentation] Multipotent neural crest-derived stem cells in bone marrow, dorsal rootganglia,and facial skin in adult rodent. (2007)
  • Author(s): Nagoshi N, Shibata S, Nakamura M, et. al.
  • Organizer: The 37th Annual Meeting of Society for Neuroscience,
  • Place of Presentation: San Diego,CA,USA
  • Year and Date: 2007-11-05
• [Presentation] 損傷脊髄に田尾する神経堤幹細胞の移植治療 (2007)
  • Author(s): 名越慈人, 芝田晋介, 松崎有未, 岡野栄之, 戸山芳昭, 中村雅也
  • Organizer: 第26回日本運動移植再生医学研究会
  • Place of Presentation: 静岡
  • Year and Date: 2007-10-27
• [Presentation] Multipotent neural crest-derived stem cells in bone marrow,dorsal root ganglia,and facial skin in adult rodent. (2007)
  • Author(s): Nagoshi N, Shibata S, Nakamura M, et. al.
  • Organizer: 5^<th> Annual meeting of International Society for Stem
  • Place of Presentation: Boston,MA,USA
  • Year and Date: 2007-06-17
• [Presentation] Multipotent neural crest-derived stem cells in bone marrow, dorsal root ganglia, and facial skin in adult rodent (2007)
  • Author(s): Nagoshi N, Shibata S, Nakamura M, Matsuzaki Y, Toyama Y, Okano H
  • Organizer: The 37th Annual Meeting of Society for Neuroscience
  • Place of Presentation: San Diego, CA, USA
• [Presentation] 中枢神経再生へ向けた神経堤幹細胞の可能性 (2007)
  • Author(s): 名越慈人, 芝田晋介, 中村雅也, 松崎有未, 戸山芳昭, 岡野栄之
  • Organizer: 第28回日本炎症再生医学会
  • Place of Presentation: 東京
• [Presentation] Isolation and characterization of neural crest stem cells in adult rodent (2007)
  • Author(s): Nagoshi N, Shibata S, Nakamura M, Nagai Y, Okano JH, Matsuzaki Y, Toyama Y, Okano H
  • Organizer: 5^<th>Annual meeting of International Society forStem cell research
  • Place of Presentation: Cairns, Australia
• [Book] 神経堤幹細胞を用いた移植研究~神経再生を目指して~臨床整形(43(7)) (2008)
  • Author(s): 名越慈人, 中村雅也, 岡野栄之, 戸山芳昭
  • Publisher: 医学書院
• [Book] 遺伝子医学MOOK9, ますます広がる分子イメージング技術 (2008)
  • Author(s): 辻収彦, 中村雅也, 岡野James洋尚, 岡野栄之, 戸山芳昭
  • Publisher: メディカルドゥ社
• [Remarks] Nagoshi N, Nakamura N, Shibata S, Kugamai G, Matsuzaki Y, Okano H, ToyamaY : Characterization of neural crest stem cells as the source oftransplantation for spinal cord injury. Cervical Spine Research Society Basic research award (2008.12.5 Austin, USA)