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Development of a prophylactic vaccine effective against a broader spectrum of HPVs associated with cervical cancer and basic research on therapeutic HPV vaccine for cervical cancer

Research Project

Project/Area Number 19390424
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Obstetrics and gynecology
Research InstitutionUniversity of Tsukuba

Principal Investigator

YOSHIKAWA Hiroyuki  University of Tsukuba, 大学院・人間総合科学研究科, 教授 (40158415)

Co-Investigator(Kenkyū-buntansha) YASUGI Toshiharu  がん・感染症センター, 都立駒込病院婦人科, 医長 (20251267)
KAWANA Kei  東京大学, 医学部附属病院, 助教 (60311627)
松本 光司  筑波大学, 大学院・人間総合科学研究科, 講師 (30302714)
Co-Investigator(Renkei-kenkyūsha) MATSUMOTO Kouji  筑波大学, 大学院・人間総合科学研究科, 講師 (30302714)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2009: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2008: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2007: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
KeywordsHPV / ワクチン / 子宮頸癌 / L2 / VLP / VLPワクチン / L2ワクチン / キメラワクチン / 中和抗体 / バキュロウイルス / エピトープ
Research Abstract

The HPV 16/18 vaccine for prevention of cervical cancer is principally type-specific and can protect approximately 70% of cervical cancer. We developed a prophylactic vaccine effective against a broader spectrum of HPVs associated with cervical cancer. We now need clinical trial for clinical application.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (196 results)

All 2010 2009 2008 2007

All Journal Article (98 results) (of which Peer Reviewed: 60 results) Presentation (94 results) Book (4 results)

  • [Journal Article] Oral immunization with a Lactobacillus casei vaccine expressing human papillomavirus (HPV) type 16 E7 is an effective strategy to induce mucosal cytotoxic lymphocytes against HPV16 E72010

    • Author(s)
      Adachi K, Kawana K(13人中2番目), Yasugi T(13人中11番目), et al.
    • Journal Title

      Vaccine (in press)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Outcomes of Fertility-Sparing Surgery for Stage I Epithelial Ovarian Cancer : A Proposal for Patient Selection2010

    • Author(s)
      Satoh T, Yoshikawa H (20人中20番目)
    • Journal Title

      JCO 28(10)

      Pages: 1727-1732

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The Optimal Debulking After Neoadjuvant Chemotherapy in Ovarian Cancer ; Proposal Based on Interval Look During Upfront Surgery Setting Treatment2010

    • Author(s)
      Onda T, Yoshikawa H (5人中2番目), Yasugi T (5人中3番目), et al.
    • Journal Title

      Jpn J Clin Oncol 40(1)

      Pages: 36-41

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A Phase III Trial of Paclitaxel plus Carboplatin Versus Paclitaxel plus Cisplatin in Stage IVB, Persistent or Recurrent Cervical Cancer : Gynecologic Cancer Study Group/Japan Clinical Oncology Group Study (JCOG0505)2010

    • Author(s)
      Saito I, Yoshikawa H (8人中7番目), et al.
    • Journal Title

      Jpn J Clin Oncol 40(1)

      Pages: 90-93

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A Phase III Trial of Paclitaxel plus Carboplatin Versus Paclitaxel plusCisplatin in Stage IVB, Persistent or Recurrent Cervical Cancer : Gynecologic Cancer Study Group/Japan Clinical Oncology Group Study(JCOG0505).2010

    • Author(s)
      Saito I
    • Journal Title

      Jpn J Clin Oncol 40(1)

      Pages: 90-93

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Outcomes of Fertility-Sparing Surgery for Stage I Epithelial Ovarian Cancer : A Proposal for Patient Selection.2010

    • Author(s)
      Satoh T
    • Journal Title

      JCO (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oral immunization with a Lactobacillus casei vaccine expressing human papillomavirus(HPV)type 16 E7 is an effective strategy to induce mucosal cytotoxic lymphocytes against HPV16 E7.2010

    • Author(s)
      Adachi K
    • Journal Title

      Vaccine (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 子宮頸部の中等度異形成(CIN2)-局所療法を行うか.経過観察か?-2010

    • Author(s)
      沖明典
    • Journal Title

      産婦人科の実際 59(3)

      Pages: 465-471

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Identification of nucleolin as a protein that binds to human papillomavirus type 16 DNA2009

    • Author(s)
      Sato H, Kawana K (11人中7番目), et al.
    • Journal Title

      Biochem Biophys Res Commun 387(3)

      Pages: 525-530

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] MR and CT findings of leiomyomatosis peritonealis disseminata with emphasis on assisted reproductive technology as a risk factor2009

    • Author(s)
      Tanaka YO, Yoshikawa H(9人中9番目), et al. Noguchi M, Minami M
    • Journal Title

      Br J Radiol 82(975)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Human papillomavirus infections among Japanese women : age-related prevalence and type-specific risk for cervical cancer2009

    • Author(s)
      Onuki M, Matsumoto K (12人中2番目), Yoshikawa H (12人中12番目), et al
    • Journal Title

      Cancer Sciences 100(7)

      Pages: 1312-1316

    • NAID

      10027192443

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Human papillomavirus vaccines : current issues & future2009

    • Author(s)
      Kawana K (3人中1番目), Yasugi T (3人中2番目), et al.
    • Journal Title

      Indian J Med Res.Review 130(3)

      Pages: 341-347

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Immunogenicity, reactogenicity and safety of human papillomavirus 16/18 AS04-adjuvanted vaccine in Japanese women : interim analysis of a phase II double-blind, randomized controlled trial at Month 72009

    • Author(s)
      Konno R, Yoshikawa H (5人中5番目), et al.
    • Journal Title

      Int J Gynecol Cancer 19(5)

      Pages: 905-911

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Feasibility study of neoadjuvant chemotherapy followed by interval debulking surgery for stage III/IV ovarian, tubal, and peritoneal cancers : Japan Clinical Oncology Group Study JCOG02062009

    • Author(s)
      Onda T, Yoshikawa H (7人中7番目), et al.
    • Journal Title

      Gynecol Oncol 113(1)

      Pages: 57-62

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Stem cells of GATA1-related leukemia undergo pernicious changes after 5-fluorouracil treatment2009

    • Author(s)
      Abe K, Yoshikawa H (6人中5番目), et al.
    • Journal Title

      Experimental Hematology 37(4)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nuclear location of minor capsid protein L2 is required for expression of a reporter plasmid packaged in HPV51 pseudovirions2009

    • Author(s)
      Kondo K, Yoshikawa H (6人中5番目), et al.
    • Journal Title

      Virology 394(2)

      Pages: 259-265

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A phase III randomized trial comparing neoadjuvant chemotherapy and upfront debulking surgery is indispensable as a basis for changing the standard treatment of advanced Mullerian cancer2009

    • Author(s)
      Onda T, Yoshikawa H (2人中2番目)
    • Journal Title

      Gynecol Oncol 114(2)

      Pages: 371-372

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] ヒトパピローマウイルス2009

    • Author(s)
      吉川裕之
    • Journal Title

      がん分子標的治療(メディカルレビュー社、東京) 7(2)

      Pages: 54-57

    • Related Report
      2009 Final Research Report
  • [Journal Article] ヒトパピローマウイルス2009

    • Author(s)
      吉川裕之
    • Journal Title

      日本医師会雑誌(日本医師会 (東京)) 138(4)

      Pages: 697-699

    • Related Report
      2009 Final Research Report
  • [Journal Article] ヒトパピローマウイルス (HPV) ワクチン2009

    • Author(s)
      吉川裕之
    • Journal Title

      化学療法の領域(医学ジャーナル社(東京)) 25(7)

      Pages: 65-70

    • Related Report
      2009 Final Research Report
  • [Journal Article] 日本におけるHPVワクチンの接種-現状と展望-2009

    • Author(s)
      吉川裕之
    • Journal Title

      産婦人科治療(永井書店) 99(3)

      Pages: 311-315

    • Related Report
      2009 Final Research Report
  • [Journal Article] HPVワクチンによる癌予防2009

    • Author(s)
      吉川裕之
    • Journal Title

      感染制御(EDIXi出版部(東京)) 5(4)

      Pages: 343-346

    • NAID

      40016901372

    • Related Report
      2009 Final Research Report
  • [Journal Article] 「ワクチンへの期待」子どもの健康科学2009

    • Author(s)
      吉川裕之
    • Journal Title

      日本子ども健康科学学会 10(1)

      Pages: 23-27

    • Related Report
      2009 Final Research Report
  • [Journal Article] Feasibility study of neoadjuvant chemotherapy followed by interval debulking surgery for stage III/IV ovarian, tubal, and peritoneal cancers : Japan Clinical Oncology Group Study JCOG02062009

    • Author(s)
      Onda T
    • Journal Title

      Gynecol.Oncol 113(1)

      Pages: 57-62

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Immunogenicity, reactogenicity and safety of human papillomavirus 16/18 ASO 4-adjuvanted vaccine in Japanese women : interim analysis of a phase II double-blind, randomized controlled trial at Month 7.2009

    • Author(s)
      Konno R
    • Journal Title

      Int J Gynecol Cancer 19(5)

      Pages: 905-911

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Stem cells of GATA1-related leukemia undergo pernicious changes after 5-fluorouracil treatment.2009

    • Author(s)
      Abe K
    • Journal Title

      Experimental Hematology 37(4)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MR and CT findings of leiomyomatosis peritonealis disseminata with emphasis on assisted reproductive technology as a risk factor.2009

    • Author(s)
      Tanaka YO
    • Journal Title

      Br J Radiol 82(975)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Human papillomavirus infections among Japanese women : age-related prevalence and type-specific risk for cervical cancer.2009

    • Author(s)
      Onuki M
    • Journal Title

      Cancer Sciences 100(7)

      Pages: 1312-1316

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A phase III randomized trial comparing neoadjuvant chemotherapy and upfront debulking surgery is indispensable as a basis for changing the standard treatment of advanced Mullerian cancer.2009

    • Author(s)
      Onda T
    • Journal Title

      Gynecol Oncol 114(2)

      Pages: 371-372

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nuclear location of minor capsid protein L2 is required for expression of a reporter plasmid packaged in HPV51 pseudovirions.2009

    • Author(s)
      Kondo K
    • Journal Title

      Virology 394(2)

      Pages: 259-265

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Human papillomavirus vaccines : current issues & future.2009

    • Author(s)
      Kawana K
    • Journal Title

      Indian J Med Res 130(3)

      Pages: 341-347

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of nucleolin as a protein that binds to human papillomavirus type 16 DNA2009

    • Author(s)
      Sato H
    • Journal Title

      Biochem Biophys Res Commun. 387(3)

      Pages: 525-530

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] XI.各臓器癌に対する薬物路湯法 婦人科癌 子宮癌・絨毛癌2009

    • Author(s)
      吉川裕之
    • Journal Title

      日本臨牀 67(増刊号1)

      Pages: 700-704

    • Related Report
      2009 Annual Research Report
  • [Journal Article] ヒトパピローマウイルス2009

    • Author(s)
      吉川裕之
    • Journal Title

      がん分子標的治療 7(2)

      Pages: 54-57

    • Related Report
      2009 Annual Research Report
  • [Journal Article] ヒトパピローマウイルス2009

    • Author(s)
      吉川裕之
    • Journal Title

      日本医師会雑誌 138(4)

      Pages: 697-699

    • Related Report
      2009 Annual Research Report
  • [Journal Article] ヒトパピローマウイルス(HPV)ワクチン2009

    • Author(s)
      吉川裕之
    • Journal Title

      化学療法の領域 25(7)

      Pages: 65-70

    • Related Report
      2009 Annual Research Report
  • [Journal Article] HPVワクチンによる癌予防2009

    • Author(s)
      吉川裕之
    • Journal Title

      感染制御 5(4)

      Pages: 343-346

    • NAID

      40016901372

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 日本におけるHPVワクチンの接種-現状と展望2009

    • Author(s)
      吉川裕之
    • Journal Title

      産婦人科治療 99(3)

      Pages: 311-315

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 子宮がん2009

    • Author(s)
      沖明典
    • Journal Title

      Journal of Integrated Medicine(JIM) 19(12)

      Pages: 894-899

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 6.婦人科癌術前化学療法2009

    • Author(s)
      吉川裕之
    • Journal Title

      婦人科癌化学療法ポケットマニュアル

      Pages: 132-141

    • Related Report
      2009 Annual Research Report
  • [Journal Article] ワクチンへの期待2009

    • Author(s)
      吉川裕之
    • Journal Title

      子どもの健康科学 10(1)

      Pages: 23-27

    • Related Report
      2009 Annual Research Report
  • [Journal Article] ワクチンの現状と展望2009

    • Author(s)
      吉川裕之
    • Journal Title

      ウイルス 59(2)

      Pages: 243-248

    • NAID

      10026383862

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Human papillomavirus infections among Japanese women: age-related prevalence and type-specific risk for cervical cancer2009

    • Author(s)
      Onuki M, et al
    • Journal Title

      Cander Sciences 100(7)

      Pages: 1312-1316

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MR and CT findings of leiomyomatosis peritonealis disseminata with emphasis on assisted reproductive technology as a risk factor.2009

    • Author(s)
      Tanaka YO, et al
    • Journal Title

      Br J Radiology 82(975)

      Pages: 44-47

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Stem cells of GATAl-related leukemia undergo pernicious changes after 5-fluorouracil treatment.2009

    • Author(s)
      Abe K, et al
    • Journal Title

      Experimental Hematology 37(4)

      Pages: 435-445

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Immunogenicity, reactogenicity and safety of human papillomavirus (HPV)-16/18 ASO4-adjuvanted vaccine in Japanese women: interim analysis of a phase II double-blind, randomized controlled trial at Month 72009

    • Author(s)
      Konno R, et al
    • Journal Title

      Int J Gynecol Cancer (印刷中)(in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Feasibility study of neoadjuvant chemotherapy followed by interval debulking surgery for stage III/IV ovarian, tubal, and peritoneal cancers: Japan ClinicalOncology Group Study JCOG0206.2009

    • Author(s)
      Onda T, et al
    • Journal Title

      Gynecol Oncol 113(1)

      Pages: 7-62

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Japan Clinical Oncology Group. Phase III trial of upfront debulking surgery versus neoadjuvant chemotherapy for stage III/IV ovarian, tubal and peritoneal cancers : Japan Clinical Oncology Group Study JCOG06022008

    • Author(s)
      Onda T, Yoshikawa H (8人中8番目)
    • Journal Title

      Jpn J Clin Oncol 38(1)

      Pages: 74-77

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Carcinosarcoma of the uterus : MR findings2008

    • Author(s)
      Tanaka YO, Yoshikawa H (5人中4番目), et al.
    • Journal Title

      J Magn Reson Imaging 28(2)

      Pages: 434-439

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of tumor regression rate of uterine cervical squamous cell carcinoma during external beam and intracavitary radiotherapy2008

    • Author(s)
      Ohara K, Yoshikawa H (7人中7番目), et al.
    • Journal Title

      Radiat Med 26(9)

      Pages: 526-532

    • NAID

      10024434138

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Silent venous thromboembolism before treatment in endometrial cancer and the risk factors2008

    • Author(s)
      Satoh T, Matsumoto K (11人中2番目), Yoshikawa H (11人中11番目), et al.
    • Journal Title

      Br J Cancer 99(7)

      Pages: 1034-1039

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neutralizing antibodies against human papillomavirus types of 16, 18, 31, 52, and 58 in the serum samples from Japanese women with low grade cervical intraepithelial neoplasia2008

    • Author(s)
      Ochi H, Matsumoto K (9人中3番目), Yasugi T (9人中5番目), Yoshikawa H (9人中8番目), et al.
    • Journal Title

      Clin Vaccine Immunol 15(10)

      Pages: 1536-1540

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Modification of human papillomavirus-like particle vaccine by insertion of the cross-reactive L2-epitopes2008

    • Author(s)
      Kondo K, Yoshikawa H (5人中4番目), et al.
    • Journal Title

      J Med Virol 80(5)

      Pages: 841-846

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 「性感染症の最前線HPV感染と子宮頸癌-これまでの研究の流れ-」臨床とウイルス2008

    • Author(s)
      吉川裕之
    • Journal Title

      日本臨床ウイルス学会 36(5)

      Pages: 377-383

    • Related Report
      2009 Final Research Report
  • [Journal Article] Comparison of tumor regression rate of uterine cervical squamous cell carcinoma during external beam and intracavitary radiotherapy.2008

    • Author(s)
      Ohara K, et al
    • Journal Title

      Radiat Med 26(9)

      Pages: 526-532

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neutralizing antibodies against human papillomavirus types of 16, 18, 31, 52, and 58 in the serum samples from Japanese women with low grade cervical intraepithelial neoplasia.2008

    • Author(s)
      Ochi H, et al
    • Journal Title

      Clin Vaccine Immunol 15(10)

      Pages: 1536-1540

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Silent venous thromboembolism before treatment in endometrial cancer and the risk factors.2008

    • Author(s)
      Satoh T, et al
    • Journal Title

      Br J Cancer 99(7)

      Pages: 1034-1039

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Carcinosarcoma of the uterus: MR findings2008

    • Author(s)
      Tanaka YO, et al
    • Journal Title

      J Magn Reson Imaging 28(2)

      Pages: 434-439

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Modification of human papillomavirus-like particle vaccine by insertion of the cross-reactive L2-epitopes.2008

    • Author(s)
      Kondo K, et al
    • Journal Title

      J Med Virol 80(5)

      Pages: 841-846

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Japan Clinical Oncology Group. Phase III trial of upfront debulking surgery versus neoadjuvant chemotherapy for stage III/IV ovarian, tubal and peritoneal cancers: Japan Clinical Oncology Group Study TCOG0602.2008

    • Author(s)
      Onda T, et al
    • Journal Title

      Jpn J Clin Oncol 38(1)

      Pages: 74-77

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 性感染症の最前線HPV感染と子宮頸癌-これまでの研究の流れ-2008

    • Author(s)
      吉川裕之
    • Journal Title

      臨床とウイルス 36(5)

      Pages: 377-383

    • Related Report
      2008 Annual Research Report
  • [Journal Article] -HPVワクチンによる子宮頸がん予防-欧米で70%、我が国では60%が可能2008

    • Author(s)
      吉川裕之
    • Journal Title

      Medical Tribune 41(29)

      Pages: 56-56

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 子宮頸がん検診におけるHPV testingと細胞診2008

    • Author(s)
      沖明典、他
    • Journal Title

      産科と婦人科 75(12)

      Pages: 1788-1798

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 子宮頸部HPV感染症の疫学症の疫学研究とワクチンによる予防2008

    • Author(s)
      吉川裕之
    • Journal Title

      感染症学雑誌 82(6)

      Pages: 609-612

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 子宮頸癌予防ワクチン(HPV-16/18 ASO4 アジュバントワクチン)の本邦における臨床的有用性2008

    • Author(s)
      今野良、他
    • Journal Title

      産科と婦人科 75(11)

      Pages: 1701-1712

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 子宮頸癌ワクチンの原理と臨床効果2008

    • Author(s)
      吉川裕之
    • Journal Title

      癌の基礎から臨床ヘ-ベンチからベッドサイドへ- 0

      Pages: 171-174

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 新規ワクチンの開発と期待 パピローマウイルスワクチン2008

    • Author(s)
      吉川裕之
    • Journal Title

      目本臨林 66(10)

      Pages: 1957-1960

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 未感染者でのワクチンの有効性を示すと同時にcatch-up vaccinatiohの限界を示した報告2008

    • Author(s)
      吉川裕之
    • Journal Title

      CRITICAL EYES 26

      Pages: 2-2

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 子宮頸癌における予防の重要性〜HPVワクチンの可能性と変革を求められる日本の社会構造2008

    • Author(s)
      吉川裕之
    • Journal Title

      FOCUS on ONCOLOGY 8

      Pages: 18-20

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 産婦人科臨床の難題を解く-私はこうしているIII婦人科癌治療【子宮頸癌】「HPVワクチンによる子宮頸癌予防戦略は?」2008

    • Author(s)
      吉川裕之
    • Journal Title

      臨床婦人科産科 62(4)

      Pages: 571-574

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Modification of human papillomavirus-like particle vaccine by insertion of the cross-reactive L2-epitopes.2008

    • Author(s)
      Kondo K, et. al.
    • Journal Title

      J Med Virol. 80(5)(in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Outcomes of Fertility-Sparing Surgery for Stage I Epithelial Ovarian Cancer : A Proposal for Patient Selection. JCO, in pressnation for the failure of neoadjuvant chemotherapy to improve outcomes after radiotherapy for locally advanced uterine cervical cancer from the standpoint of the tumor regression rate2007

    • Author(s)
      Ohara K, Yoshikawa H (12人中11番目), et al. ExplaSatoh T, Yoshikawa H (20人中20番目)
    • Journal Title

      Radiat Med 25

      Pages: 53-59

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Magnetic resonance findings of primary uterine malignant lymphoma2007

    • Author(s)
      Goto N, Yoshikawa H (5人中4番目), et al.
    • Journal Title

      Magn Reson Med Sci 6(1)

      Pages: 7-13

    • NAID

      130000097486

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Combined phospho-Akt and PTEN expressions associated with post-treatment hysterectomy after conservative progestin therapy in complex atypical hyperplasia and stage Ia, G1 adenocarcinoma of the endometrium2007

    • Author(s)
      Minaguchi T, Yasugi T (12人中8番目), Yoshikawa H (12人中11番目), et al.
    • Journal Title

      Cancer Letters 248(1)

      Pages: 112-122

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neutralization of HPV16, 18, 31, and 58 pseudovirions with antisera induced by immunizing rabbits with synthetic peptides representing segments of the HPV16 minor capsid protein L2 surface region2007

    • Author(s)
      Kondo K, Yoshikawa H, (6人中5番目)
    • Journal Title

      Virology 358(2)

      Pages: 266-272

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Treatment with paclitaxel plus carboplatin, alone or with irradiation, of advanced or recurrent endometrial carcinoma2007

    • Author(s)
      Arimoto T, Yasugi T (7人中3番目), Yoshikawa H (7人中4番目), Kawana K (7人中5番目), et al.
    • Journal Title

      Gynecol Oncol 104(1)

      Pages: 32-35

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tissue factor expression as a possible determinant of thromboembolism in ovarian cancer2007

    • Author(s)
      Uno K, Matsumoto K (12人中6番目), Yoshikawa H (12人中11番目), et al.
    • Journal Title

      Br J Cancer 96(2)

      Pages: 290-295

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fertility-Sparing Treatment with Medroxyprogesterone Acetate for Endometrial Carcinoma and Atypical Hyperplasia in Young Women : A Multicenter Phase II Study2007

    • Author(s)
      Ushijima K, Yoshikawa H (20人中3番目), Yasugi T (20人中5番目), et al.
    • Journal Title

      J Clin Oncol 25(19)

      Pages: 2798-2803

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] High incidence of silent venous thromboembolism before treatment in ovarian cancer2007

    • Author(s)
      Satoh T, Matsumoto K (12人中8番目), Yoshikawa H (12人中12番目), et al.
    • Journal Title

      Br J Cancer 97(8)

      Pages: 1053-1057

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] ワクチンの展望1ヒトパピローマウイルス (HPV) ワクチン2007

    • Author(s)
      吉川裕之
    • Journal Title

      治療学(ライフサイエンス出版株式会社) 41(10)

      Pages: 55-57

    • Related Report
      2009 Final Research Report
  • [Journal Article] HPVワクチンと子宮頸癌の予防2007

    • Author(s)
      吉川裕之
    • Journal Title

      産婦人科治療(永井書店) 95(3)

      Pages: 299-302

    • Related Report
      2009 Final Research Report
  • [Journal Article] Combined phospho-Akt and PTEN expressions associated with post-treatment hysterectomy after conservative progestin therapy in complex atypical hyperplasia and stage Ia, G1 adenocarcinoma of the endometrium.2007

    • Author(s)
      Minaguchi T, et. al.
    • Journal Title

      Cancer Letters 248(1)

      Pages: 112-122

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neutralization of HPV16, 18, 31, and 58 pseudovirions with antisera induced by immunizing rabbits with synthetic peptides representing segments of the HPV16 minor capsid protein L2 surface region.2007

    • Author(s)
      Kondo K, et. al.
    • Journal Title

      Virology 358(2)

      Pages: 266-272

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Treatment with paclitaxel plus carboplatin, alone or with irradiation, of advanced or recurrent endometrial carcinoma.2007

    • Author(s)
      Arimoto T, et. al.
    • Journal Title

      Gynecol Oncol 104(1)

      Pages: 32-35

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tissue factor expression as a possible determinant of thromboembolism in ovarian cancer.2007

    • Author(s)
      Uno K, et. al.
    • Journal Title

      Br J Cancer. 96(2)

      Pages: 290-295

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Explanation for the failure of neoadjuvant chemotherapy to improve outcomes after radiotherapy for locally advanced uterine cervical cancer from the standpoint of the tumor regression rate.2007

    • Author(s)
      Ohara K, et. al.
    • Journal Title

      Radiat Med 25(2)

      Pages: 53-59

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Magnetic resonance findings of primary uterine malignant lymphoma.2007

    • Author(s)
      Goto N, et. al.
    • Journal Title

      Magn Reson Med Sci 6(1)

      Pages: 7-13

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fertility-Sparing Treatment with Medroxyprogesterone Acetate for Endometrial Carcinoma and Atypical Hyperplasia in Young Women: A Multicenter Phase II Study.2007

    • Author(s)
      Ushijima K, et. al.
    • Journal Title

      J Clin Oncol 25(19)

      Pages: 2798-2803

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High incidence of silent venous thromboembolism before treatment in ovarian cancer.2007

    • Author(s)
      Satoh T, et. al.
    • Journal Title

      Br J Cancer 97(8)

      Pages: 1053-1057

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Japan Clinical Oncology Group. Phase III trial of upfront debulking surgery versus neoadjuvant chemotherapy for stage III/IV ovarian, tubal and peritoneal cancers: Japan Clinical Oncology Group Study JCOGO602.2007

    • Author(s)
      Onda T, et. al.
    • Journal Title

      Jpn J Clin Oncol 38(1)

      Pages: 74-77

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 婦人科腫瘍に対する術前化学療法2007

    • Author(s)
      吉川 裕之、他
    • Journal Title

      医学のあゆみ 221(4)

      Pages: 285-290

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 子宮頸癌広汎性手術の留意点2007

    • Author(s)
      吉川 裕之
    • Journal Title

      産婦人科手術 18

      Pages: 145-149

    • Related Report
      2007 Annual Research Report
  • [Journal Article] HPVワクチンの現況2007

    • Author(s)
      吉川 裕之
    • Journal Title

      化療ニュース 16(1)

      Pages: 1-3

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 腹式広汎子宮全摘出の留意点(別冊2007

    • Author(s)
      吉川 裕之
    • Journal Title

      産婦人科手術 18

      Pages: 145-149

    • Related Report
      2007 Annual Research Report
  • [Journal Article] HPVワクチンと子宮頸癌の予防2007

    • Author(s)
      吉川 裕之
    • Journal Title

      産婦人科治療 95(3)

      Pages: 299-302

    • Related Report
      2007 Annual Research Report
  • [Journal Article] ワクチンの展望1 ヒトパピローマウイルス(HPV)ワクチン2007

    • Author(s)
      吉川 裕之
    • Journal Title

      治療学 41(10)

      Pages: 55-57

    • Related Report
      2007 Annual Research Report
  • [Journal Article] IV.性感染症 3,ヒトパピローマ感染症2007

    • Author(s)
      松本光司、他
    • Journal Title

      日本内科学会雑誌 96(11)

      Pages: 2456-2464

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 子宮頸部発がんの危険因子としての喫煙に関する研究2007

    • Author(s)
      吉川 裕之
    • Journal Title

      喫煙科学Smoking Science 22(4)

      Pages: 4-4

    • Related Report
      2007 Annual Research Report
  • [Presentation] 子宮頸癌予防戦略としてのワクチン2010

    • Author(s)
      吉川裕之
    • Organizer
      京都HPVワクチン学術講演会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-27
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸癌予防戦略としてのワクチン2010

    • Author(s)
      吉川裕之
    • Organizer
      京都HPVワクチン学術講演会
    • Place of Presentation
      京都オークラホテル(京都)
    • Year and Date
      2010-03-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] ワクチンによる子宮頸癌予防戦略2010

    • Author(s)
      吉川裕之
    • Organizer
      第8回神奈川県県域地区産婦人科研修会
    • Place of Presentation
      神奈川
    • Year and Date
      2010-03-11
    • Related Report
      2009 Final Research Report
  • [Presentation] ワクチンによる子宮頸癌予防戦略2010

    • Author(s)
      吉川裕之
    • Organizer
      第8回神奈川県県域地区産婦人科研修会
    • Place of Presentation
      小田急ホテルセンチュリー相模大野(神奈川)
    • Year and Date
      2010-03-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] 子宮頸がんの予防戦略としてのワクチン2010

    • Author(s)
      吉川裕之
    • Place of Presentation
      鹿児島
    • Year and Date
      2010-02-24
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸がんの予防戦略としてのワクチン2010

    • Author(s)
      吉川裕之
    • Organizer
      山水会
    • Place of Presentation
      城山観光ホテル(鹿児島)
    • Year and Date
      2010-02-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 子宮頸癌予防戦略としてのワクチン2010

    • Author(s)
      吉川裕之
    • Organizer
      平成21年度大分県医師会がん精密検診協力医療機関研修会 大分県医師会
    • Place of Presentation
      大分
    • Year and Date
      2010-01-31
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸癌予防戦略としてのワクチン2010

    • Author(s)
      吉川裕之
    • Organizer
      平成21年度大分県医師会がん精密検診協力医療機関研修会
    • Place of Presentation
      大分県医師会館(大分)
    • Year and Date
      2010-01-31
    • Related Report
      2009 Annual Research Report
  • [Presentation] 講演「子宮頸がん予防ワクチンについて」2010

    • Author(s)
      吉川裕之
    • Organizer
      鳥取産婦人科医会・西部小児科医会合同特別講演会
    • Place of Presentation
      鳥取
    • Year and Date
      2010-01-21
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸がん予防ワクチンについて2010

    • Author(s)
      吉川裕之
    • Organizer
      鳥取産婦人科医会・西部小児科医会合同特別講演会
    • Place of Presentation
      米子全日空ホテル(鳥取)
    • Year and Date
      2010-01-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] ワクチンによる子宮頸がん予防戦略2010

    • Author(s)
      吉川裕之
    • Organizer
      がん医療水準的てん化研修会「バーチャルスライド、ベセスダシステム、HPVに関する研修会」
    • Place of Presentation
      札幌
    • Year and Date
      2010-01-09
    • Related Report
      2009 Final Research Report
  • [Presentation] ワクチンによる子宮頸がん予防戦略2010

    • Author(s)
      吉川裕之
    • Organizer
      がん医療水準的てん化研修会「バーチャルスライド、ベセスダシステム、HPVに関する研修会
    • Place of Presentation
      札幌医科大学(北海道)
    • Year and Date
      2010-01-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] 子宮頸癌予防のためのHPVワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      長野市医師会学術講演会
    • Place of Presentation
      長野
    • Year and Date
      2009-12-17
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸癌予防のためのHPVワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      長野市医師会学術講演会
    • Place of Presentation
      ホテルメトロポリタン長野(長野)
    • Year and Date
      2009-12-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] HPVワクチンによる子宮頸癌予防2009

    • Author(s)
      吉川裕之
    • Organizer
      平成21年度第3回滋賀県産婦人科医会
    • Place of Presentation
      滋賀県 (大津)
    • Year and Date
      2009-12-06
    • Related Report
      2009 Final Research Report
  • [Presentation] HPVワクチンによる子宮頸癌予防2009

    • Author(s)
      吉川裕之
    • Organizer
      平成21年度第3回滋賀県産婦人科医会
    • Place of Presentation
      大津プリンスホテル(滋賀県)
    • Year and Date
      2009-12-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] 子宮頸がん予防とHPVワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      婦人科臨床懇話会HPV研究会 愛知県産婦人科医会
    • Place of Presentation
      愛知
    • Year and Date
      2009-11-28
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸がん予防とHPVワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      婦人科臨床懇話会HPV研究会
    • Place of Presentation
      中央ビル(愛知)
    • Year and Date
      2009-11-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] 子宮頸癌予防戦略としてのワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      第1回県南県西子宮頸癌予防セミナー
    • Place of Presentation
      つくば
    • Year and Date
      2009-11-26
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸癌予防戦略としてのワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      第1回県南県西子宮頸癌予防セミナー
    • Place of Presentation
      つくば国際会議場(茨城)
    • Year and Date
      2009-11-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] 子宮頸がんとは?発生状況、原因と症状・治療法2009

    • Author(s)
      吉川裕之
    • Organizer
      子宮頸がん啓発のための市民公開講座-子宮頸がんを予防しましょう!(日本産科婦人科学会・日本小児学会・子宮頸がんを征圧をめざす専門会会議)
    • Place of Presentation
      女性と仕事の未来館(東京)
    • Year and Date
      2009-11-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] ワクチンによる子宮頸癌予防戦略2009

    • Author(s)
      吉川裕之
    • Organizer
      第282回筑後ブロック産婦人科医会研修会
    • Place of Presentation
      久留米
    • Year and Date
      2009-11-18
    • Related Report
      2009 Final Research Report
  • [Presentation] ワクチンによる子宮頸癌予防戦略2009

    • Author(s)
      吉川裕之
    • Organizer
      第282回筑後ブロック産婦人科医会研修会
    • Place of Presentation
      ホテルニュープラザ久留米(福岡)
    • Year and Date
      2009-11-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] HPVワクチンの効果と安全性2009

    • Author(s)
      吉川裕之
    • Organizer
      子宮頸がん予防のためのプロフェッショナルワークショップ
    • Place of Presentation
      東京
    • Year and Date
      2009-11-15
    • Related Report
      2009 Final Research Report
  • [Presentation] HPVワクチンの効果と安全性2009

    • Author(s)
      吉川裕之
    • Organizer
      子宮頸がん予防のためのプロフェッショナルワークショップ
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2009-11-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] 特別講演「子宮頸がんの予防ワクチンについて」2009

    • Author(s)
      吉川裕之
    • Organizer
      山梨ウイルス研究会
    • Place of Presentation
      山梨
    • Year and Date
      2009-10-30
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸がんの予防ワクチンについて2009

    • Author(s)
      吉川裕之
    • Organizer
      山梨ウイルス研究会
    • Place of Presentation
      古名屋ホテル(山梨)
    • Year and Date
      2009-10-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] 子宮頸がん予防ワクチンについて2009

    • Author(s)
      吉川裕之
    • Organizer
      第16回もしもし医学セミナー
    • Place of Presentation
      NTT東関東病院(東京)
    • Year and Date
      2009-10-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] HPVワクチンによる子宮頸癌予防2009

    • Author(s)
      吉川裕之
    • Organizer
      第235回広島市臨床産婦人科医会研修会
    • Place of Presentation
      広島
    • Year and Date
      2009-09-24
    • Related Report
      2009 Final Research Report
  • [Presentation] HPVワクチンによる子宮頸癌予防2009

    • Author(s)
      吉川裕之
    • Organizer
      第235回広島市臨床産婦人科医会研修会
    • Place of Presentation
      広島市医師会館(広島)
    • Year and Date
      2009-09-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] ワクチンによる子宮頸がんの予防2009

    • Author(s)
      吉川裕之
    • Organizer
      北陸ウイルス研究会
    • Place of Presentation
      金沢
    • Year and Date
      2009-09-05
    • Related Report
      2009 Final Research Report
  • [Presentation] ワクチンによる子宮頸がんの予防2009

    • Author(s)
      吉川裕之
    • Organizer
      北陸ウイルス研究会
    • Place of Presentation
      金沢エクセルホテル東急(石川)
    • Year and Date
      2009-09-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] 子宮頸がん予防のためのHPVワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      第10回臨床腫瘍夏期セミナー
    • Place of Presentation
      東京
    • Year and Date
      2009-07-23
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸がん予防のためのHPVワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      第10回臨床腫瘍夏期セミナー
    • Place of Presentation
      ヤクルトホール(東京)
    • Year and Date
      2009-07-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] 子宮頸癌ワクチンの展望(日医生涯教育協力講座 セミナー「ウイルス感染症をめぐる最新の動向」)2009

    • Author(s)
      吉川裕之
    • Organizer
      茨城県医師会会館
    • Place of Presentation
      水戸
    • Year and Date
      2009-04-11
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸癌ワクチンの展望2009

    • Author(s)
      吉川裕之
    • Organizer
      日医生涯教育協力講座
    • Place of Presentation
      茨城県医師会会館(茨城)
    • Year and Date
      2009-04-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] 「子宮頸がんの現状とワクチン」子宮がんセミナー2009

    • Author(s)
      吉川裕之
    • Organizer
      公明党女性委員会
    • Place of Presentation
      東京
    • Year and Date
      2009-02-28
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸がんの現状とワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      子宮がんセミナー
    • Place of Presentation
      東京
    • Year and Date
      2009-02-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] HPVワクチン開発と導入、その課題-HPV感染と子宮頸癌、ワクチンによる予防の課題-2009

    • Author(s)
      吉川裕之
    • Organizer
      第一回HPVワクチン推奨ワーキンググループ 日本産婦人科医会
    • Place of Presentation
      東京
    • Year and Date
      2009-02-20
    • Related Report
      2009 Final Research Report
  • [Presentation] HPVワクチン開発と導入、その課題-HPV 感染と子宮頸癌、ワクチンによる予防の課題-2009

    • Author(s)
      吉川裕之
    • Organizer
      第一回HPVワクチン推奨ワーキンググループ
    • Place of Presentation
      東京
    • Year and Date
      2009-02-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] 子宮頸がんの現状とHPVワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      世界対がんデー公開シンポジウム-子宮頸がん征圧を目指して-
    • Place of Presentation
      東京 (癌研)
    • Year and Date
      2009-02-04
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸がんの現状とHPVワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      世界対がんデー公開シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2009-02-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 子宮頸がんワクチンの現状と展望について2009

    • Author(s)
      吉川裕之
    • Organizer
      第24回奈良感染症研究会
    • Place of Presentation
      奈良
    • Year and Date
      2009-01-24
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 子宮頸癌ワクチンの展望2009

    • Author(s)
      吉川裕之
    • Organizer
      日医生涯教育協力講座 (セミナー・ウイルス感染症における予防と治療)
    • Place of Presentation
      高知
    • Year and Date
      2009-01-17
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸癌ワクチンの展望2009

    • Author(s)
      吉川裕之
    • Organizer
      日医生涯教育協力講座(セミナー・ウイルス感染症における予防と治療)
    • Place of Presentation
      高知
    • Year and Date
      2009-01-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] ワクチンによる子宮頸癌の予防2009

    • Author(s)
      吉川裕之
    • Organizer
      第24回北海道抗ウイルス療法研究会
    • Place of Presentation
      札幌
    • Related Report
      2009 Final Research Report
  • [Presentation] CIN患者におけるHPV血清中和抗体2009

    • Author(s)
      越智寛幸, 松本光司, 吉川裕之, 他
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] 次世代型HPVワクチンの開発2009

    • Author(s)
      近藤一成, 吉川裕之, 他
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] 我が国におけるHPV感染とタイプ別子宮頸癌リスク-スクリーニングとワクチンのための基礎データ-2009

    • Author(s)
      小貫麻美子, 松本光司, 他
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] HPVワクチンの展望2009

    • Author(s)
      吉川裕之
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸癌予防ワクチン (HPV-16/18AS04) の本邦における中間解析と臨床的意義2009

    • Author(s)
      今野良, 吉川裕之
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸癌予防ワクチン(HPV-16/18AS04)の本邦における中間解析と臨床的意義2009

    • Author(s)
      今野良
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      グランドプリンスホテル京都(京都)
    • Related Report
      2009 Annual Research Report
  • [Presentation] CIN患者におけるHPV血清中和抗体2009

    • Author(s)
      越智寛幸
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      グランドプリンスホテル京都(京都)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 次世代型HPVワクチンの開発2009

    • Author(s)
      近藤一成
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      グランドプリンスホテル京都(京都)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 我が国におけるHPV感染とタイプ別子宮頸癌リスク-スクリーニングとワクチンのための基礎データ-2009

    • Author(s)
      小貫麻美子
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      グランドプリンスホテル京都(京都)
    • Related Report
      2009 Annual Research Report
  • [Presentation] IL-10プロモーター領域の遺伝子変異と子宮頸部発癌の関連2009

    • Author(s)
      中尾砂里
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      グランドプリンスホテル京都(京都)
    • Related Report
      2009 Annual Research Report
  • [Presentation] HPVワクチンの展望2009

    • Author(s)
      吉川裕之
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      グランドプリンスホテル京都(京都)
    • Related Report
      2009 Annual Research Report
  • [Presentation] ワクチンによる子宮頸癌の予防2009

    • Author(s)
      吉川裕之
    • Organizer
      第24回北海道抗ウイルス療法研究会
    • Place of Presentation
      京王プラザホテル(札幌)
    • Related Report
      2009 Annual Research Report
  • [Presentation] ワクチンへ期待2008

    • Author(s)
      吉川裕之
    • Organizer
      第10回こども健康科学学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-12-06
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 我が国におけるヒトパピローマウイルス16型・18型感染-筑波大データによるワクチン効果の試算-2008

    • Author(s)
      小貫麻美子、他
    • Organizer
      第160日本産科婦人科学会地方部会例会
    • Place of Presentation
      つくば
    • Year and Date
      2008-11-08
    • Related Report
      2008 Annual Research Report
  • [Presentation] ワクチンによる子宮頸がんの予防2008

    • Author(s)
      吉川裕之
    • Organizer
      長崎県産婦人科学術講演会
    • Place of Presentation
      長崎
    • Year and Date
      2008-11-07
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] HPVワクチンによる子宮頸がんの予防2008

    • Author(s)
      吉川裕之
    • Organizer
      第11回熊本ウイルス感染症研究会
    • Place of Presentation
      熊本
    • Year and Date
      2008-10-16
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 電流検出型DNAチップ法によるHPVタイピング試薬の臨床的有用性2008

    • Author(s)
      佐藤豊実, 吉川裕之, 他
    • Organizer
      第40回日本臨床検査自動科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2008-10-10
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] HPVと関連疾患2008

    • Author(s)
      吉川裕之
    • Organizer
      HPV Vaccine International Meeting
    • Place of Presentation
      東京
    • Year and Date
      2008-09-19
    • Related Report
      2009 Final Research Report
  • [Presentation] HPVと関連疾患2008

    • Author(s)
      吉川裕之
    • Organizer
      HPV Vaccine International Meeting
    • Place of Presentation
      横浜
    • Year and Date
      2008-09-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] 子宮頸部発がんの危険因子としての喫煙に関する研究2008

    • Author(s)
      吉川裕之
    • Organizer
      平成19年度喫煙科学研究財団発表会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-24
    • Related Report
      2008 Annual Research Report
  • [Presentation] OC安心処方のためのエビデンス-OCと悪性腫瘍-2008

    • Author(s)
      吉川裕之
    • Organizer
      平成20年度 女性のプライマリ・ケアを担う医療者のためのOC実践セミナー
    • Place of Presentation
      東京
    • Year and Date
      2008-03-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] 子宮頸がんとHPV-最近の話題-2008

    • Author(s)
      吉川裕之
    • Organizer
      第27会日本論証細胞学会埼玉県支部・埼玉県臨床細胞医会学術集会
    • Place of Presentation
      埼玉
    • Year and Date
      2008-03-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] 子宮頸癌とウイルスの関係〜発癌の機序や予防(ワクチン)の視点から〜2008

    • Author(s)
      吉川裕之
    • Organizer
      「FOCUS on ONCOLOGY」取材
    • Place of Presentation
      つくば
    • Year and Date
      2008-01-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] 子宮頸癌とHPV-頸癌の Pathogenesis とHPVの疫学2008

    • Author(s)
      吉川裕之
    • Organizer
      第116回日本産科婦人科学会関東連合地方部会
    • Place of Presentation
      栃木
    • Related Report
      2009 Final Research Report
  • [Presentation] The Standard Treatment of Cervical Cancer in Asian View-Point2008

    • Author(s)
      Yoshikawa H
    • Organizer
      The 3rd Biennial Conference Asia Oceania research organization on Genital Infection & Neoplasia (AOGIN 2008)
    • Place of Presentation
      Seoul, Korea.
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸部HPV感染症の疫学研究とワクチンによる予防2008

    • Author(s)
      吉川裕之
    • Organizer
      第82回日本感染症学会総会・学術講演会
    • Place of Presentation
      島根
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 子宮頸癌とHPV-頸癌のPathogenesis とHPV の疫学2008

    • Author(s)
      吉川裕之
    • Organizer
      第116回日本産科婦人科学会関東連合地方部会
    • Place of Presentation
      栃木
    • Related Report
      2008 Annual Research Report
  • [Presentation] 我が国におけるHPV感染とタイプ別子宮頸部発癌リスク-スクリーニングとワクチンのための基礎データー2008

    • Author(s)
      小貫麻美子、他
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Related Report
      2008 Annual Research Report
  • [Presentation] The Standard Treatment of Cervical Cancer in Asian View-Point2008

    • Author(s)
      Yoshikawa H
    • Organizer
      The 3rd Bienni-al Conference Asia Oceania research organization on Genital Infection & Neoplasia (AOGIN 2008)
    • Place of Presentation
      Seoul
    • Related Report
      2008 Annual Research Report
  • [Presentation] 子宮頸がんとHPV;疫学研究と予防ワクチン2008

    • Author(s)
      吉川裕之
    • Organizer
      第107回日本皮膚科学会総会
    • Place of Presentation
      京都
    • Related Report
      2008 Annual Research Report
  • [Presentation] 子宮頸部前癌病変の自然消失・進展と喫煙の関連2008

    • Author(s)
      松本光司、他
    • Organizer
      第60回日本産科婦人科学会・総会・学術講演会
    • Place of Presentation
      横浜
    • Related Report
      2008 Annual Research Report
  • [Presentation] 女性性器のHPV感染2007

    • Author(s)
      吉川裕之
    • Organizer
      日本性感染症学会第20回学術大会
    • Place of Presentation
      東京
    • Year and Date
      2007-12-02
    • Related Report
      2007 Annual Research Report
  • [Presentation] 「子宮頚癌に対する治療-NACかCCRTか?」において術前化学療法適応賛成の立場から2007

    • Author(s)
      吉川裕之
    • Organizer
      第43回婦人科腫瘍学会術集会 クリニカルディベート
    • Place of Presentation
      鳥取
    • Year and Date
      2007-11-24
    • Related Report
      2007 Annual Research Report
  • [Presentation] 手術療法適応賛成の立場から-子宮頸部扁平上皮癌I/II期bulkyに対するNACが有用である可能性は低い-2007

    • Author(s)
      吉川裕之
    • Organizer
      第43回日本婦人科腫瘍学会
    • Place of Presentation
      米子
    • Year and Date
      2007-11-24
    • Related Report
      2007 Annual Research Report
  • [Presentation] 子宮頸がんワクチンの現状と展望2007

    • Author(s)
      吉川裕之
    • Organizer
      第25回日本産婦人科学感染症研究会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-16
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Presentation] 子宮頸がんの現状と予防への期待2007

    • Author(s)
      吉川裕之
    • Organizer
      Dr.Ian Frazer 来日メディアセミナー
    • Place of Presentation
      東京
    • Year and Date
      2007-06-12
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮頸がんの現状と予防への期待2007

    • Author(s)
      吉川裕之
    • Organizer
      Dr. Ian Frazer 来日メディアセミナー
    • Place of Presentation
      東京
    • Year and Date
      2007-06-12
    • Related Report
      2007 Annual Research Report
  • [Presentation] HPVワクチンの展望2007

    • Author(s)
      吉川裕之
    • Organizer
      日産婦会福島地方部会総会・春期学術集会並びに福島県産婦人科医会総会
    • Place of Presentation
      福島
    • Year and Date
      2007-04-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] 子宮癌の予防に向けて2007

    • Author(s)
      吉川裕之
    • Organizer
      第48回日本母性衛生学会総会・学術集会
    • Place of Presentation
      つくば
    • Related Report
      2009 Final Research Report
  • [Presentation] HPV感染による子宮頸癌への対応2007

    • Author(s)
      吉川裕之
    • Organizer
      第22回関東甲信静支部ウィルス研究部会総会
    • Place of Presentation
      茨城
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Presentation] Development of novel HPV genotyping chip system using electrochemical detection technology and Non-PCR amplification technology2007

    • Author(s)
      Satoh T, Matsumoto K, Yoshikawa H, et al.
    • Organizer
      24th international papillomavirus conference and clinical workshop
    • Place of Presentation
      Beijing, China
    • Related Report
      2009 Final Research Report
  • [Presentation] Development of novel HPV genotyping chip system using electrochemical detetion technology2007

    • Author(s)
      Satoh T, Matsumoto K, Yoshikawa H, et al.
    • Organizer
      2007 AACC Annal Meeting
    • Place of Presentation
      California. USA
    • Related Report
      2009 Final Research Report
  • [Presentation] 集団検診要請検者のHPV感染の短期follow-up成績2007

    • Author(s)
      小貫麻美子、吉川裕之、他
    • Organizer
      第59回日本産婦人科学会
    • Place of Presentation
      京都
    • Related Report
      2007 Annual Research Report
  • [Presentation] Development of novel HPV genotyping chip system using electrochemical detetion technology.2007

    • Author(s)
      Satoh T, et. al.
    • Organizer
      AACC Annal Meeting
    • Place of Presentation
      California
    • Related Report
      2007 Annual Research Report
  • [Presentation] 子宮癌の予防に向けて2007

    • Author(s)
      吉川裕之
    • Organizer
      第48回日本母性衛生学会総会・学術集会
    • Place of Presentation
      茨城(つくば)
    • Related Report
      2007 Annual Research Report
  • [Presentation] 子宮頸癌に対する治療效果の比較:外部照射VS腔内照射-前向き臨床研究の予備解析結果-2007

    • Author(s)
      大原 潔、他
    • Organizer
      第45回日本癌治療学会総会
    • Place of Presentation
      京都
    • Related Report
      2007 Annual Research Report
  • [Presentation] Development of novel HPV genotyping chip system using electrochemical detection technology and Non-PCR amplification technology.2007

    • Author(s)
      Satoh T, et. al.
    • Organizer
      24th international papillomavirus conference and clinicalworkshop
    • Place of Presentation
      Beijing
    • Related Report
      2007 Annual Research Report
  • [Presentation] 若年HPV感染者の子宮頸部細胞診像2007

    • Author(s)
      佐藤豊実、他.
    • Organizer
      第46回日本臨床細胞学会春期大会
    • Place of Presentation
      仙台
    • Related Report
      2007 Annual Research Report
  • [Book] Human papillomavirus type 16 capsid proteins : Immunogenecity and possible use as prophylactic vaccine antigens(Ed. Cheng R. H., Miyamura T.)Structure-based study of viral replication2008

    • Author(s)
      Kanda T, Kawana K, Yoshikawa H
    • Publisher
      World Scientific Publishing
    • Related Report
      2009 Final Research Report
  • [Book] 今日の治療指針 私はこう治療している2008

    • Author(s)
      吉川裕之
    • Total Pages
      2
    • Publisher
      子宮頸癌
    • Related Report
      2007 Annual Research Report
  • [Book] World Scientific2007

    • Author(s)
      KandaT, et. al.
    • Total Pages
      22
    • Publisher
      Human Papillomavirus Type 16 Capsid Proteins:Immunogenicity and Possible Use as Prophylactic Vaccine Antigens
    • Related Report
      2007 Annual Research Report
  • [Book] 内科学2007

    • Author(s)
      吉川裕之
    • Total Pages
      2
    • Publisher
      ヒトパピローマウイルス
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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