| Project/Area Number |
19390484
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
YOSHIYAMA Masahiro Okayama University, 大学院・医歯薬学総合研究科, 教授 (10201071)
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| Co-Investigator(Kenkyū-buntansha) |
NISHITANI Yoshihiro 岡山大学, 大学院・医歯薬学総合研究科, 准教授 (60325123)
YAMAJI Kozo 岡山大学, 岡山大学病院, 講師 (30374531)
IZAWA Shunji 岡山大学, 大学院・医歯薬学総合研究科, 助教 (20273998)
SHINNO Yasuo 岡山大学, 大学院・医歯薬学総合研究科, 助教 (60403490)
DOI Junichi 岡山大学, 大学院・医歯薬学総合研究科, 助教 (90379842)
OHMAE Masanori 岡山大学, 大学院・医歯薬学総合研究科, 助教 (10403487)
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| Co-Investigator(Renkei-kenkyūsha) |
SANO Hidehiko 北海道大学, 大学院・歯学研究科, 教授 (90205998)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥12,740,000 (Direct Cost: ¥9,800,000、Indirect Cost: ¥2,940,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2008: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2007: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
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| Keywords | 保存修復学 / 象牙質再生療法 / EVA+C / 修復象牙質 / EVA / ナノハイドロキシアパタイト / 脱灰象牙質 / 象牙質 / 引張り接着強さ / セルフェッチングプライマー / ナノ・ハイドロキシアパタイト |
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| Research Abstract |
The mineralization accelerating adhesion materials that added EVA+C (RMSB) were produced experimentally, and we studied the bond strength and biocompatibility. Bond strength decreased with increase of the EVA+C addition ratio. The RMSB group showed a tendency to growth similar to Control at the early phase, and cell count was higher than an SB (Superbond) at high ratio of EVA+C group. SBP30 and 7P (SB/EVA+C=40wt%/60wt%) showed a high bond strength and a good cell proliferation. Invivo, 7P had weaker inflammation than an SB and mineralized tissue formation was good. High adhesive property and biocompatibility was oftained by RMSB-7P.
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