A prospective study regarding the onset of neuropathic pain in the orofacial region in human

• Project/Area Number: 19390495
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: 補綴理工系歯学
• Research Institution: Osaka University
• Principal Investigator: ISHIGAKI Shoichi Osaka University, 歯学部・附属病院, 講師 (40212865)
• Co-Investigator(Kenkyū-buntansha): YATANI Hirofumi 大阪大学, 大学院・歯学研究科, 教授 (80174530)
• Research Collaborator: UCHIDA Masanori 大阪大学, 歯学部・附属病院, 医員 (10573454)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥15,600,000 (Direct Cost: ¥12,000,000、Indirect Cost: ¥3,600,000); Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000); Fiscal Year 2007: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
• Keywords: 神経因性疼痛 / 発生機序 / ヒト / インプラント / 三叉神経 / 頸神経 / 経神経

Research Abstract

A recent increase in dental implant surgeries will increase a risk for post-operative neuropathic pain. The aim of this prospective cohort study is to evaluate the influence of dental implant surgeries on pain thresholds. It was found that the decrease in the pain threshold not only in the nerve area of the implant surgery but also in the adjacent nerve areas after the surgical procedures was a common finding even though patients did not complain of their pain.

Research Products

• [Presentation] Pain threshold of the trigeminal nerve after the implant surgery (2010)
  • Author(s): 石垣尚一、小野清美、宮内鉄平、矢谷博文
  • Organizer: The 88th General Session of the International Association for Dental Research (IADR)
  • Place of Presentation: Barcelona、Spain
• [Presentation] インプラント埋入手術が三叉神経領域の疼痛閾値に及ぼす影響に関する予備的検討 (2010)
  • Author(s): 小野清美、石垣尚一、内田昌範、宮内鉄平、福田修二、矢谷博文
  • Organizer: 日本補綴歯科学会第119回学術大会
  • Place of Presentation: 東京
• [Presentation] インプラント埋入手術が三叉神経領域の疼痛閾値に及ぼす影響の予備的検討 (2009)
  • Author(s): 小野清美、石垣尚一、廣川雅之、鈴木英史、内田昌範、宮内鉄平、矢谷博文
  • Organizer: 平成20年度日本補綴歯科学会関西支部学術大会
  • Place of Presentation: 和歌山
  • Year and Date: 2009-02-08
• [Presentation] The effect of the implant surgery on the pain threshold of the trigeminal nerve region (2009)
  • Author(s): 小野清美、石垣尚一、矢谷博文
  • Organizer: The 6th Congress of the European Federation of IASP (International Association for the Study of Pain) Chapters (EFIC)
  • Place of Presentation: Lisbon、Portugal
• [Presentation] インプラント埋入手術が三叉神経領域の疼痛閾値に及ぼす影響に関する予備的検討;第2報 (2009)
  • Author(s): 小野清美、石垣尚一、矢谷博文
  • Organizer: 第22回日本顎関節学会学術大会・第14回日本口腔顔面痛学会学術大会共催集会
  • Place of Presentation: 東京
• [Presentation] The effect of the implant surgery on the pain threshold of the trigeminal nerve region : A preliminary report (2009)
  • Author(s): 小野清美、石垣尚一、宮内鉄平、内田昌範、矢谷博文
  • Organizer: The 6th Biennial Meeting of Asian Academy of Prosthodontics (AAP)
  • Place of Presentation: Seoul、Korea
• [Presentation] The effect of the implant surgery on the pain threshold of the trigeminal nerve region : A preliminary report. (2009)
  • Author(s): Ono K, Ishigaki S, Miyauchi T, Uchida M, Yatani H
  • Organizer: The 6th Biennial Meeting of Asian Academy of Prosthodontcs (AAP)
  • Place of Presentation: Seoul, Korea
• [Presentation] インプラント埋入手術が三叉神経領域および隣接領域の疼痛閾値に及ぼす影響 (2009)
  • Author(s): 小野清美、石垣尚一、矢谷博文
  • Organizer: 第22回日本本顎関節学会学術大会・第14回日本口腔顔面痛学会学術大会共催集会
  • Place of Presentation: 東京
• [Presentation] The effect of the implant surgery on the pain threshold of the trigeminal nerve region. (2009)
  • Author(s): Ishigaki S, Ono K, Yatani H
  • Organizer: The 6th Congress of the European Federation of IASP (International Association for the Study of Pain) Chapters (EFIC)
  • Place of Presentation: Lisbon, Portugal
• [Presentation] クレンチングが三叉神経支配領域の疼痛閾値に及ぼす影響 (2008)
  • Author(s): 石垣尚一
  • Organizer: 社団法人日本補綴歯科学会関西支部学術大会
  • Place of Presentation: 大阪
  • Year and Date: 2008-01-27
• [Presentation] Sex Difference in Thermal Pain Threshold after Teeth Clenching (2008)
  • Author(s): Ishigaki s, Miyauchi T, Yatani H, Ono K.
  • Organizer: The 86th General Session of the International Association for Dental Research
  • Place of Presentation: Toronto, Canada
• [Presentation] Sex Difference in Thermal Pain Threshold in the Trigeminalnerve area (2008)
  • Author(s): Ishigaki S, Yatani H.
  • Organizer: The 12th World Congress on Pain
  • Place of Presentation: Glasgow, Scotland, UK
• [Remarks] ホームページ等
  • URL: http://www.dent.osaka-u.ac.jp/graduate/course/prost1.html