Development of a new orthodontic direct bonding system capable of reducing the bond strength on debonding.

• Project/Area Number: 19390499
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: 補綴理工系歯学
• Research Institution: Iwate Medical University
• Principal Investigator: ARAKI Yoshima Iwate Medical University, 歯学部, 教授 (20005036)
• Co-Investigator(Kenkyū-buntansha): MIURA Hiroyuki 岩手医科大学, 歯学部, 教授 (00048563) ; TAIRA Masayuki 岩手医科大学, 歯学部, 准教授 (60179398) ; IIZUKA Yasuyuki 岩手医科大学, 歯学部, 助教 (80311934) ; SASAKI Kaori 岩手医科大学, 歯学部, 助教 (00364373)
• Research Collaborator: TANAKA Shigeru まこと矯正歯科医院, 副院長
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000); Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000); Fiscal Year 2008: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2007: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
• Keywords: 歯科用材料 / 歯科理工学 / 歯学 / 歯列矯正 / 矯正装置 / 接着システム / ディボンディング / 矯正用接着システム / 接着強度制御 / 可視光線応答型酸化チタン / 光触媒 / セラミックブラケット / 耐水性 / マルチブラケットシステム / 接着 / ディボンデング / 接着耐久性 / プラスアイオノマーセメント

Research Abstract

In orthodontic treatment, orthodontic appliances are directly bonded to tooth with adhesives. The bond strength should be reduced to remove the appliance without damaging the tooth surface when debonding. We studied the effects of water penetration into the adhesive layer and deterioration of adhesive itself by photo sensitive catalysis on the bond strength. As a result, the orthodontic direct bonding systems capable of reducing the bond strength on debonding were developed.

Research Products

• [Journal Article] Bond strength of an orthodontic bonding material and adhesion energy of artificial saliva to an experimental titanium bracket. (2010)
  • Author(s): Iizuka, Y., Araki, Y., Miura, H.
  • Journal Title: Orthodontic Waves
  • Peer Reviewed
• [Journal Article] Bond strength of an orthodontic bonding material and adhesion energy of artificial saliva to an experimental titanium bracket. (2010)
  • Author(s): Iizuka, Y., Araki, Y., et.al.
  • Journal Title: Orthodontic Waves (掲載許可)(未定)
  • Peer Reviewed
• [Journal Article] Microscopic observations and inflammatory cytokine productions of human macrophage phagocytising submicron titanium particles. (2009)
  • Author(s): Taira, M., Kagiya, T., Harada, H., Sasaki, M., Kimura, S., Narushima, T., Nezu, T., Araki, Y.
  • Journal Title: J Mater Sci Mater Med. 20
  • Peer Reviewed
• [Journal Article] Preparation and in vivo evaluation of apatite/collagen packed composite by alternate immersion method and Newton press. (2009)
  • Author(s): Taira, M., Nezu, T., Sasaki, K., Saitoh, S., Kagiya, T., Harada, H., Takada, Y., Araki, Y.
  • Journal Title: J Biomed Mater Res B Appl Biomater 90 Pages: 566-573
  • Peer Reviewed
• [Journal Article] DNA microarray analysis of the effects of LPS-stimulation and IC50 nickel ions on gene expressions of mose macrophage-like cell line RAW264 (2009)
  • Author(s): Taira, M., Sasaki, M., Sasaki, K., Saitoh, S., Nezu, T., Kimura, S., Araki, Y.
  • Journal Title: Nono-Bioscience 1 Pages: 59-69
  • Peer Reviewed
• [Journal Article] Gene expression analyses of human macrophage phagocytizing sub-μtitanium particles by allergy DNA chip(GenopalTM) (2009)
  • Author(s): Taira, M., Nezu, T., Sasaki, M., Kimura, S., Kagiya, T., Harada, H., Narushima, T., Araki, Y.
  • Journal Title: Biomed Mater Eng 19 Pages: 63-70
  • Peer Reviewed
• [Journal Article] Microscopic observations and inflammatory cytokine productions of human macrophage phagocytising submicron titanium particles. (2009)
  • Author(s): Taira, M., Araki, Y., et.al.
  • Journal Title: J Mater Sci Mater Med (掲載許可)(未定)
  • Peer Reviewed
• [Journal Article] Preparation and in vivo evaluation of apatite/collagen packed composite by alternate immersion method and Newton press (2009)
  • Author(s): Taira, M., Araki, Y., et.al.
  • Journal Title: J Biomed Mater Res B Appl Biomater 90 Pages: 566-573
  • Peer Reviewed
• [Journal Article] Hardness and composition of solution-treated Ag-Pd-Cu-Au alloy microstructures (2008)
  • Author(s): Saitoh, S., Sasaki, K., Nezu, T., Taira, M., Araki, Y.
  • Journal Title: Mater Trans 49(10) Pages: 2360-2364
  • NAID: 10024326348
  • Peer Reviewed
• [Journal Article] Tex/EDX observation of micro-beads of magnetically activated cell sorting(MACS) system and separation trial of mouse mesenchymal stem cells from bone marrow cells by MACS system (2008)
  • Author(s): Taira, M., Sasaki, K., Saitoh, S., Nezu, T., Kagiya, T., Harada, H., Sasaki, M., Kimura, S., Hirata, I., Araki, Y.
  • Journal Title: J Oral Tissue Eng 6(1) Pages: 33-40
  • Peer Reviewed
• [Journal Article] Effect of pH and addition of salt on the adsorption behavior of lysozyme on the gold, silica and titania surfaces observed by quartz crystal microbalance with dissipation monitoring. (2008)
  • Author(s): Nezu, T., Masuyama, T., Sasaki, K., Saitoh, S., Taira, M., Araki, Y.
  • Journal Title: Dent Mater J 27(4) Pages: 573-580
  • NAID: 110006861868
  • Peer Reviewed
• [Journal Article] Dose-dependent effects of Ni(II) ions on production of three inflammatory cytokines(TNF-a, IL-1b and IL-6), superoxide dismutase(SOD) and free radical NO by murine macrophage-like RAW264 cells with or without LPS-stimulation (2008)
  • Author(s): Taira, M., Sasaki, M., Kimura, S., Araki, Y.
  • Journal Title: J Mater Sci Mater Med 19(5) Pages: 2173-2178
  • Peer Reviewed
• [Journal Article] Effect of pH and addition of salt on the adsorption Behavior of lysozyme on the gold, silica and titania Surfaces observed by quartz crystal microbalance with Dissipation monitoring (2008)
  • Author(s): Nezu, T., Masuyama, T., Sasaki, K., Saitoh, S., Taira, M., Araki, Y.
  • Journal Title: Dental Materials Journal 27 Pages: 573-580
  • NAID: 110006861868
  • Peer Reviewed
• [Journal Article] TEM/EDX observation of micro-beads of magnetically activated cell sorting (MACS) system and separation trial of Maouse mesenchymal stem celIs from bone marrow cells by MACS system (2008)
  • Author(s): Taira, M., Sasaki, K., Saitoh, S., Nezu, T., Kagiya, T., Harada, H., Sasaki, M., Kimura, S., Hirata, I., Araki, Y.
  • Journal Title: J. Oral Tissue Eng. 6 Pages: 33-40
  • Peer Reviewed
• [Journal Article] Hardness and composition of solution-treated Ag-Pd-Cu-Au alloy microstructure (2008)
  • Author(s): Saitoh, S., Sasaki, K., Nezu, T., Taira, M., Araki, Y.
  • Journal Title: Mater. Trans. 49 Pages: 2360-2364
  • NAID: 10024326348
  • Peer Reviewed
• [Presentation] 高濃度の銅イオンがマクロファージに及ぼす傷害作用に関する研究 (2009)
  • Author(s): 平雅之、荒木吉馬
  • Organizer: 第31回バイオマテリアル学会大会
  • Place of Presentation: 京都
  • Year and Date: 2009-11-17
• [Presentation] ティッシュコンディショナーの粘弾性的性質の比較 (2009)
  • Author(s): 齋藤設雄、佐々木かおり、根津尚史、平雅之、荒木吉馬
  • Organizer: 第54回日本歯科理工学会学術講演会
  • Place of Presentation: 鹿児島
  • Year and Date: 2009-10-02
• [Presentation] バイオフィルム類似多糖吸着層の粘弾性-菌体外多糖層の壊れにくさの背景- (2009)
  • Author(s): 根津尚史、佐々木かおり、齋藤設雄、平雅之、荒木吉馬
  • Organizer: 第54回日本歯科理工学会学術講演会
  • Place of Presentation: 鹿児島
  • Year and Date: 2009-10-01
• [Presentation] IC10%濃度の銅イオンで培養したマクロファージのTEM形態観察と細胞内銅イオン量のEDX測定 (2009)
  • Author(s): 平雅之、佐々木かおり、齋藤設雄、根津尚史、荒木吉馬
  • Organizer: 第54回日本歯科理工学会学術講演会
  • Place of Presentation: 鹿児島
  • Year and Date: 2009-10-01
• [Presentation] 球状および棒状タンパク質2成分系の吸着と吸着層の粘弾性 (2009)
  • Author(s): 根津尚史、荒木吉馬
  • Organizer: 第62回コロイドおよび界面化学討論会
  • Place of Presentation: 岡山
  • Year and Date: 2009-09-19
• [Presentation] 歯科理工学の将来像を考える-40年を顧みて- (2009)
  • Author(s): 荒木吉馬
  • Organizer: 平成21年度日本歯科理工学会・北海道東北支部夏期セミナー
  • Place of Presentation: 郡山
  • Year and Date: 2009-07-25
• [Presentation] 鋳造後高温保持・急冷した金銀パラジウム合金の組織変化と器械的性質 (2009)
  • Author(s): 齋藤設雄、佐々木かおり、根津尚史、平雅之、荒木吉馬
  • Organizer: 第53回日本歯科理工学会学術講演会
  • Place of Presentation: 東京
  • Year and Date: 2009-04-12
• [Presentation] コラーゲンのアパタイトQCMセンサーへの吸着による擬象牙質センサーの試作 (2009)
  • Author(s): 根津尚史、佐々木かおり、齋藤設雄、平雅之、荒木吉馬
  • Organizer: 第53回日本歯科理工学会学術講演会
  • Place of Presentation: 東京
  • Year and Date: 2009-04-12
• [Presentation] 銅イオンがマウス多形核白血球(好中球)の活性酸素産生に及ぼす濃度依存的影響 (2009)
  • Author(s): 平雅之、佐々木かおり、齋藤設雄、根津尚史、荒木吉馬
  • Organizer: 第53回日本歯科理工学会学術講演会
  • Place of Presentation: 東京
  • Year and Date: 2009-04-11
• [Presentation] マクロファージ(PMA刺激THP-1細胞)によるサブマイクロン・チタン微粒子の貪食評価 (2008)
  • Author(s): 平雅之、佐々木かおり、齋藤設雄、根津尚史、荒木吉馬
  • Organizer: 日本バイオマテリアル学会シンポジウム2008
  • Place of Presentation: 東京
  • Year and Date: 2008-11-18
• [Presentation] Effect of high-conncentration ID10% copper ions on macrophage (2008)
  • Author(s): Taira, M., Kagiya, T., Harada, H., Sasaki, M., Kimura, S., Araki, Y.
  • Organizer: Academy of Dental Materials 2008 Conference
  • Place of Presentation: Wuertzburg(Germany)
  • Year and Date: 2008-10-02
• [Presentation] コラーゲン-リゾチーム相互作用のpH依存性のQCM-Dを用いた解析 (2008)
  • Author(s): 根津尚史、佐々木かおり、齋藤設雄、平雅之、荒木吉馬
  • Organizer: 第52回日本歯科理工学会学術講演会
  • Place of Presentation: 大阪
  • Year and Date: 2008-09-20
• [Presentation] 交互浸漬法とニュートンプレスによって調製したコラーゲン・アパタイト複合体の骨伝導能の評価 (2008)
  • Author(s): 平雅之、荒木吉馬
  • Organizer: 第6回日本再生歯科医学会学術大会
  • Place of Presentation: 東京
  • Year and Date: 2008-09-09
• [Presentation] QCM-Dを用いた球状および棒状タンパク質吸着層の粘弾性解析 (2008)
  • Author(s): 根津尚史、荒木吉馬
  • Organizer: 第61回コロイドおよび界面化学討論会
  • Place of Presentation: 福岡
  • Year and Date: 2008-09-09
• [Presentation] IC50%ニッケルイオンとLPSがマクロファージの全遺伝子発現に及ぼす影響評価 (2008)
  • Author(s): 平雅之、荒木吉馬
  • Organizer: ナノ・バイオメディカル学会第1回大会
  • Place of Presentation: 札幌
  • Year and Date: 2008-07-18
• [Presentation] コラーゲンハイドロゲルの膨潤/収縮と物質の取込/放出-複合ゲルの調整とその特性- (2008)
  • Author(s): 根津尚史、佐々木かおり、齋藤設雄、平雅之、荒木吉馬
  • Organizer: 第51回日本歯科理工学会学術講演会
  • Place of Presentation: 鶴見
  • Year and Date: 2008-04-26
• [Presentation] コラーゲンハイドロゲルの膨潤/収縮と物質の取込/放出-複合ゲルの調整とその特性- (2008)
  • Author(s): 根津尚史, 佐々木かおり, 斎藤設雄, 平雅之, 荒木吉馬
  • Organizer: 第51回日本歯科理工学会学術講演会
  • Place of Presentation: 鶴見(神奈川県)
  • Year and Date: 2008-04-26
• [Book] 、コア歯科理工学(小倉英夫, 他編、第3章歯科生体材料の用途と性質) (2008)
  • Author(s): 荒木吉馬
  • Publisher: 医歯薬出版
• [Book] コア歯科理工学(分担執筆 : 第3章歯科生体材料の用途と性質IV義歯床用材料1) (2008)
  • Author(s): 荒木吉馬, 他
  • Total Pages: 13
  • Publisher: 医歯薬出版
• [Remarks] 産業財産権出願準備中