| Project/Area Number |
19390530
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
KOZAI Katsuyuki Hiroshima University, 大学院・医歯薬学総合研究科, 教授 (10178212)
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| Co-Investigator(Kenkyū-buntansha) |
SUZUKI Junji 広島大学, 大学院・医歯薬学総合研究科, 准教授 (90263714)
HAYASHI Fumiko 広島大学, 大学院・医歯薬学総合研究科, 助教 (50325180)
YOSHIMURA Go 広島大学, 大学院・医歯薬学総合研究科, 助教 (50403530)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥14,040,000 (Direct Cost: ¥10,800,000、Indirect Cost: ¥3,240,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2008: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2007: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
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| Keywords | 歯周病原菌 / 伝播 / 小児歯周病 / 歯学 / パルスフィールド電気泳動 / DNAフィンガープリント / 歯周病原性菌 / 感染経路 / 家族内伝播 / 母子伝播 / 分子疫学 |
|---|
| Research Abstract |
The bacterial species induceed periodontitis play an important role to the appearance of disease and the progress of periodontal disease, and it is important for thinking about the prophylactic measure of periodontal disease to clarify the established time and the route of infection of the infant period. We identified a final bacterial strain by the PCR method with a primer the bacterial strain peculiar, chose two kinds of bacterial species of Prevotella nigrescens and Campylobacter rectus, examined the transmissive route with a pulse field electrophoresis unit, and admitted the spread among mother and child for a part of bacterium in this research. If the method of culturing anaerobic bacteria was able to be established, it was suggested that the transmission mechanism and the distribution of more bacteria would be interpretable.
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