| Project/Area Number |
19406013
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Parasitology (including Sanitary zoology)
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| Research Institution | Research Institute, International Medical Center of Japan |
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Principal Investigator |
KANO Shigeyuki Research Institute, International Medical Center of Japan, 研究所, 部長 (60233912)
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| Co-Investigator(Kenkyū-buntansha) |
MITAMURA Toshihide 国立国際医療センター, 研究所, 室長 (61099925)
HATABU Toshimitsu 群馬大学, 医学部, 助教 (60344917)
三田村 俊秀 国立国際医療センター(研究所), 適正技術開発移転研究部, 室長 (80268846)
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| Co-Investigator(Renkei-kenkyūsha) |
IWAGAMI Moritoshi 国立国際医療センター, 研究所, 研究員 (20392392)
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| Research Collaborator |
TANABE Kazuyuki 大阪大学, 微生物病研究所, 教授
KAWAZU Shin-Ichiro 帯広畜産大学, 原虫病センター, 教授
NAKAZAWA Shusuke 長崎大学, 熱帯医学研究所, 助教
TONGOL-RIVERA Pilarita フィリピン大学, 公衆衛生学部, 教授
LOOAREESUWAN Sornchai フィリピン大学, 公衆衛生学部, 教授
KRUDSOOD Srivicha タイ・マヒドン大学, 熱帯医学部, 教授
KHO Weon-Gyu 韓国・インジェ大学, 医学部, 教授
SOCHEAT Duong ラオス保健省・寄生虫学・昆虫学・マラリア対策センター, 所長
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2009: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2008: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2007: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
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| Keywords | 遺伝学 / 感染症 / ゲノム / 疫学 / マラリア / 国際研究者交流 / タイ:ベトナム:フィリピン:カンボジア |
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| Research Abstract |
In the malaria endemic Philippines, the level of genetic diversity of Plasmodium falciparum correlates with the local malaria endemicity. The Thai P.f.populations had been under strong chloroquine selective pressure but the Vietnamese population had not, and that the origin of chloroquine resistance in Vietnam might be different from Thailand. The genealogical origin of P. vivax populations in South Korea was from the two different populations in southern China. These findings confirm that population genetic analyses are a useful tool for epidemiology of malaria.
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