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Infra-structural organization of the international cooperative wound healing center for skin and soft tissue radiation injuries

Research Project

Project/Area Number 19406029
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Plastic surgery
Research InstitutionNagasaki University

Principal Investigator

AKITA Sadanori  Nagasaki University, 医学部・歯学部附属病院, 助教 (90315250)

Co-Investigator(Kenkyū-buntansha) 山下 俊一  長崎大学, 大学院・医歯薬学総合研究科, 教授 (30200679)
大津留 晶  長崎大学, 医学部・歯学部附属病院, 准教授 (00233198)
藤岡 正樹  長崎医療センター, 臨床研究センター, 研究員 (70393452)
長谷 敦子  長崎大学, 医学部・歯学部附属病院, 准教授 (50228037)
平野 明喜  長崎大学, 大学院・医歯薬学総合研究科, 教授 (90208835)
Co-Investigator(Renkei-kenkyūsha) 吉本 浩  長崎大学, 医学部・歯学部附属病院, 助教 (90513309)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2008: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2007: ¥12,480,000 (Direct Cost: ¥9,600,000、Indirect Cost: ¥2,880,000)
Keywords創傷治癒センター / 放射線障害 / 国際連携 / 再生医療 / 自家脂肪由来幹細胞移植 / 国際機関連携 / 国際ガイド作成 / 皮膚軟部組織創傷 / 国際協力 / 人的交流 / 姉妹校締結 / 幹細胞療法・バンク構想
Research Abstract

世界保健機関-緊急被ばく支援ネットワーク(WHO-REMPAN)のCollaboration Centerとして、(1)緊急ヒバク事例の取り扱い訓練、(2)2008年ブエノスアイレスでの第10回WHO-REMPAN会議学会発表参加、(3)2011年第11回WHO-REMPAN会議の長崎での開催を決定し、世界中でほぼ同時に情報共有できる体制を構築した。緊急ヒバクのみならず、世界中の放射線・核の医療問題の指導的立場にあり、旧ソ連邦だけではなく世界的な人脈と情報網を整備した。慢性放射線障害に対して自家脂肪組織由来幹細胞移植術を実施した。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (52 results)

All 2009 2008 2007 2005 Other

All Journal Article (17 results) (of which Peer Reviewed: 14 results) Presentation (28 results) Book (4 results) Remarks (2 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] 最新の創傷治癒・創傷治療2009

    • Author(s)
      秋田定伯
    • Journal Title

      治療 91

      Pages: 255-263

    • Related Report
      2008 Final Research Report
  • [Journal Article] A basic fibroblast growth factor accelerates and improves 2nd degree burn wound healing2008

    • Author(s)
      Akita S, Akino K, Imaizumi T, Hirano A
    • Journal Title

      Wound Repair Regen 16

      Pages: 635-641

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Human mesenchymal stem cells may involve in keloid pathogenesis2008

    • Author(s)
      Akino K, Akita S, Yakabe A, Mineda T, Hayashi T, Hirano A
    • Journal Title

      Int J Dermatol 47

      Pages: 1112-1117

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] A basic fibroblast growth factor improves lower extremity wound healing with a porcine-derived skin substitute2008

    • Author(s)
      Akita S, Akino K, Tanaka K, Anraku K, Hirnao A
    • Journal Title

      J Trauma 64

      Pages: 809-815

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] A basic fibroblast growth factor improves lower extremity wound healing with a porcine-derived skin substitute.2008

    • Author(s)
      Akita S, Akino K, Tanaka K, Anraku K, Hirnao A.
    • Journal Title

      J Trauma 64

      Pages: 809-815

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Human mesenchymal stem cells may involve in keloid pathogenesis.2008

    • Author(s)
      Akino K, Akita S, Yakabe A, Mineda T, Hayashi T, Hirano A
    • Journal Title

      Int J Dermatol 47

      Pages: 1112-1117

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A basic fibroblast growth factor accelerates and improves 2^<nd> degree burn wound healing.2008

    • Author(s)
      Akita S, Akino K, Imaizumi T, Hirano A
    • Journal Title

      Wound Repair Regen. 16

      Pages: 635-641

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] FGFによる皮膚損傷修復作用2007

    • Author(s)
      秋田定伯
    • Journal Title

      細胞 39

      Pages: 352-358

    • Related Report
      2008 Final Research Report
  • [Journal Article] FGF製剤の治療効果について2007

    • Author(s)
      秋田定伯
    • Journal Title

      PEPARS 16

      Pages: 54-63

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 臨床各領域の動向2006-2007「形成外科」2007

    • Author(s)
      秋田定伯
    • Journal Title

      治療 89

      Pages: 107-110

    • Related Report
      2008 Final Research Report
  • [Journal Article] Traumatic unilateral temporomandibular joint dislocation overlooked for more than two decades2007

    • Author(s)
      Nakashima M, Yano H, Akita S, Tokunaga K, Anraku K, Tanaka K, Hirano A
    • Journal Title

      J Craniofac Surg 18

      Pages: 1466-1470

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Acceleration of sensory neural regeneration and would healing with human mesenchymal stem cells in immunodeficient rats2007

    • Author(s)
      Imaizumi T, Akita S, Akino K, Hirano A
    • Journal Title

      Stem Cells 25

      Pages: 2956-2963

    • Related Report
      2008 Final Research Report 2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 広範囲熱傷患者における血中白血病抑制因子の上昇2007

    • Author(s)
      秋田定伯、秋野公造、今泉敏史、田中克己、安楽邦明、矢野浩規、平野明喜
    • Journal Title

      日本熱傷学会会誌 34

      Pages: 32-39

    • NAID

      10024119800

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 開頭術と顔面神経側頭枝損傷に対する神経意匠術を一期的に行った症例2007

    • Author(s)
      諸藤陽一、松尾孝之、竹下朝規、林健太郎、黒川季代子、秋田定伯、永田泉
    • Journal Title

      Neurosurgical Emergency 12

      Pages: 100-106

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 多毛を伴ったfibrous hamartoma of infancyの一例2007

    • Author(s)
      攝田麻里、安倍久仁子、林徳真吉、木下直江、今泉敏史、野中大樹、皆川知広、秋田定伯、上谷雅孝、平野明喜
    • Journal Title

      臨床皮膚科 61

      Pages: 263-266

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Combined surgical excision and radiation therapy for keloid treatment2007

    • Author(s)
      Akita S, Akino K, Yakabe A, Imaizumi T, Tanaka K, Anraku K, Yano H, Hirano A
    • Journal Title

      J Craniofac Surg 18

      Pages: 1164-1169

    • Related Report
      2008 Final Research Report 2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A basic fibroblast growth factor improves lower extremity wound healing with a porcine-derived skin substitute

    • Author(s)
      Akita S, Akino K, Tanaka K, Anraku K, Hirnao
    • Journal Title

      J Trauma (In press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 間葉系幹細胞を用いた神経再生と創傷治癒2009

    • Author(s)
      秋田定伯、今泉敏史、秋野公造、平野明喜
    • Organizer
      第1回日本創傷外科学会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-15
    • Related Report
      2008 Final Research Report
  • [Presentation] Fibroblast growth factor-2(basic fibroblast growth factor, bFGF, Fiblast spray[○!R])improves scar quality as well as accelerates wound healing in 2nd degree burns snf burn ulcer surgeries2008

    • Author(s)
      Akita S
    • Organizer
      Korean Burn Society, Invited Lecture
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2008-06-12
    • Related Report
      2008 Final Research Report
  • [Presentation] Fibroblast growth factor-2(basic f ibroblast growth factor, bFGF)improves scar quality as well as accelerates wound healing in burns2008

    • Author(s)
      Akita S
    • Organizer
      traumas, and chronic wounds
    • Place of Presentation
      Korean Wound Management Society
    • Year and Date
      2008-03-28
    • Related Report
      2008 Final Research Report
  • [Presentation] New Strategic management for local radiation injury2008

    • Author(s)
      Akita S
    • Organizer
      12th International Radiation Protection Association, Oral Presentation
    • Place of Presentation
      Buenos Aires, Argentina
    • Related Report
      2008 Final Research Report
  • [Presentation] Mesenchymal stem cell therapy for local radiation injury2008

    • Author(s)
      Akita S
    • Organizer
      12^<th> World Health Organization-Radiation Emergency Medical Preparedness and Assistance Network (WHO-REMPAN)
    • Place of Presentation
      Buenos Aires, Argentina
    • Related Report
      2008 Final Research Report
  • [Presentation] サンタモニカの風はいつも西から2008

    • Author(s)
      秋田定伯
    • Organizer
      第17回日本形成外科学会 : 基礎学術会パネルディスカッション
    • Place of Presentation
      東京
    • Related Report
      2008 Final Research Report
  • [Presentation] 創傷治癒過程のmolecular modulation2008

    • Author(s)
      秋田定伯、秋野公造、平野明喜
    • Organizer
      第17回日本形成外科学会・基礎学術集会パネルディスカッション
    • Place of Presentation
      東京
    • Related Report
      2008 Final Research Report
  • [Presentation] Fibroblast growth factor-2 (basic fibroblast growth factor, bFGF) improves scar quality as well as accelerates wound healing in burns, traumas and chronic wounds( Invited Lecture)2008

    • Author(s)
      Akita S
    • Organizer
      17^<th> European Academy of Dermatology and Venereology
    • Place of Presentation
      Paris, France
    • Related Report
      2008 Final Research Report
  • [Presentation] Fibroblast growth factor-2 (basic fibroblast growth factor, bFGF) improves scar quality as well as accelerates wound healing in burns2008

    • Author(s)
      Akita S
    • Organizer
      14^<th> Congress of International Society for Burn Injuries
    • Place of Presentation
      Montreal, Canada
    • Related Report
      2008 Final Research Report
  • [Presentation] Novel technology on surgical wound care using a basic fibroblast growth facotr in Japan2008

    • Author(s)
      Akita S
    • Organizer
      3rd European Academy of Wound
    • Place of Presentation
      Technology, Faculty Lecturer, Elancourt, France
    • Related Report
      2008 Final Research Report
  • [Presentation] II度熱傷受傷早期からのbFGF製剤使用は創傷治癒を促進し、廠痕のしつの改善につながる2008

    • Author(s)
      秋田定伯
    • Organizer
      第34回日本熱傷学会総会シンポジウム
    • Place of Presentation
      名古屋
    • Related Report
      2008 Final Research Report
  • [Presentation] 非ヒト霊長類における塩基性線維芽細胞増殖因子を用いた創傷治癒の評価2008

    • Author(s)
      秋田定伯、安楽邦明、津田雅宜、平野明喜
    • Organizer
      第34回日本熱傷学会総会
    • Place of Presentation
      名古屋
    • Related Report
      2008 Final Research Report
  • [Presentation] 再移植を必要とした二次性顎裂骨移植例の検討2008

    • Author(s)
      秋田定伯、平野明喜
    • Organizer
      第51回日本形成外科学会
    • Place of Presentation
      名古屋(口演)
    • Related Report
      2008 Final Research Report
  • [Presentation] 当科における血管奇形治療例の検討2008

    • Author(s)
      秋田定伯、田中克己、平野明喜
    • Organizer
      第51回日本形成外科学会(シンポジウム)
    • Place of Presentation
      名古屋
    • Related Report
      2008 Final Research Report
  • [Presentation] 術後電子線照射療法を併用したケロイド治療の評価について2008

    • Author(s)
      村上千佳子、秋田定伯、平野明喜
    • Organizer
      第51回日本形成外科学会
    • Place of Presentation
      名古屋(口演)
    • Related Report
      2008 Final Research Report
  • [Presentation] Mesenchymal stem cell therapy for local radiation injury2008

    • Author(s)
      Akita S.
    • Organizer
      12^<th> World Health Organization-Radiation Emergency Medical Preparedness and Assistance Network (WHO-REMPAN)会議
    • Place of Presentation
      Buenos Aires, Argentina
    • Related Report
      2008 Annual Research Report
  • [Presentation] Novel therapeutic approach using reconstructive surgery, cytokine and human bone-marrow derived mesenchymal stem cells. Scientific-Practice Conference "Cell technologies andregenerative medicine"(Invited Lecture)2007

    • Author(s)
      Akita S
    • Organizer
      Saint Petersburg State Medical Institution "Pokrovskaya Municipal Hospital"(St. Petersburg)
    • Year and Date
      2007-09-24
    • Related Report
      2008 Final Research Report
  • [Presentation] 創傷治癒促進から療痕改善へ関連する間葉系幹細胞2007

    • Author(s)
      秋田定伯
    • Organizer
      第37回日本創傷治癒学会主題演題
    • Related Report
      2008 Final Research Report
  • [Presentation] 皮膚色差解析にいる術前後、カラーマッチの検討2007

    • Author(s)
      秋田定伯、矢加部文、秋野公造、平野明喜
    • Organizer
      第16回日本形成外科学会
    • Place of Presentation
      神戸
    • Related Report
      2008 Final Research Report
  • [Presentation] 5HT2A受容体拮抗薬を血管化結合織膜弁に用いた下肢虚血モデルでの血流回復と創傷治癒促進2007

    • Author(s)
      秋田定伯、平野明喜
    • Organizer
      第16回日本形成外科学会
    • Place of Presentation
      神戸
    • Related Report
      2008 Final Research Report
  • [Presentation] 創傷治癒促進から廠痕改善へ連動するヒト間葉系幹細胞2007

    • Author(s)
      秋田定伯、秋野公造、平野明喜
    • Organizer
      第16回日本形成外科学会(シンポジウム)
    • Place of Presentation
      神戸
    • Related Report
      2008 Final Research Report
  • [Presentation] 座談会PartII~何故、私はこの研究をしているのか~2007

    • Author(s)
      秋田定伯
    • Organizer
      第16回日本形成外科学会(企画, 発表, 座長)
    • Place of Presentation
      神戸
    • Related Report
      2008 Final Research Report
  • [Presentation] Stem cell therapy and Plastic surgical management for local radiation injury(Invited Symposium)2007

    • Author(s)
      Akita S
    • Organizer
      2^<nd> International Seminar-"Radiation Medicine in Research and Practive"
    • Place of Presentation
      Wuerzburg, Germany
    • Related Report
      2008 Final Research Report
  • [Presentation] ケロイドの国際分類比較2007

    • Author(s)
      秋田定伯
    • Organizer
      第2回廠痕・ケロイド治療研究会【パネルディスカッション】《ケロイドの分類》
    • Place of Presentation
      東京
    • Related Report
      2008 Final Research Report
  • [Presentation] Easy and objective skin color analysis in plastic surgery2007

    • Author(s)
      Yakabe A, Akita S, Fujioka M, Hirano A
    • Organizer
      2007 Wound Healing Society Annual Meeting
    • Place of Presentation
      Tampa
    • Related Report
      2008 Final Research Report
  • [Presentation] Fibroblast growth factor-2 improves the quality of lower extremity wound healing2007

    • Author(s)
      Akita S, Akino K, Hirano A
    • Organizer
      2007 Wound Healing Society Annual Meeting
    • Place of Presentation
      Tampa
    • Related Report
      2008 Final Research Report
  • [Presentation] 線維芽細胞増殖因子-2は下腿創傷治癒の質を改善する(口演)2007

    • Author(s)
      秋田定伯、平野明喜
    • Organizer
      第50回日本形成外科学会
    • Place of Presentation
      東京
    • Related Report
      2008 Final Research Report
  • [Presentation] Stem cell therapy and Plastic surgical management for local radiation injury2007

    • Author(s)
      Akita S
    • Organizer
      2nd International Seminar-"Radiation Medicine in Research and Practice"
    • Place of Presentation
      Wuerzburg,Germany
    • Related Report
      2007 Annual Research Report
  • [Book] 「創傷治療」プライマリ・ケアで対処できる多種多様な"キズ"とその最新知見2009

    • Author(s)
      秋田定伯
    • Total Pages
      195
    • Publisher
      編集秋田定伯、南山堂、東京
    • Related Report
      2008 Final Research Report
  • [Book] 形成外科 外科系医師のための『創傷外科』updateI. 創傷外科総論 4. 創傷治癒に関与する細胞増殖因子2008

    • Author(s)
      秋田定伯, 平野明喜
    • Total Pages
      307
    • Publisher
      克誠堂
    • Related Report
      2008 Annual Research Report
  • [Book] Reconstruction for local radiation injuries and proposed regeneration therapy for acute systemic radiation injuries2007

    • Author(s)
      Akita S, Akino K, Hirano A, Ohtsuru A, Yamashita S
    • Total Pages
      298
    • Publisher
      Radiation Risk and Perspectives edited by Shibata Y, Namba H, Suzuki K and Tomonaga M. Elsevier, International Congress Series 1299, Amsterdam
    • Related Report
      2008 Final Research Report
  • [Book] Radiation Risk and Perspectives.International Congress Series 12992007

    • Author(s)
      Akita S, Akino K, Hirano A, Ohtsuru A, Yamashita S
    • Total Pages
      298
    • Publisher
      Elsevirer
    • Related Report
      2007 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.nagasaki-u.ac.jp/plastics/

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.nagasaki-u.ac.jp/plastics/

    • Related Report
      2007 Annual Research Report
  • [Patent(Industrial Property Rights)] 中川浩志間葉系幹細胞の培養方法および問葉系幹細胞を用いてなる培養臓器2005

    • Inventor(s)
      秋田定伯、秋野公造、中川浩志
    • Filing Date
      2005-02-10
    • Related Report
      2008 Final Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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