| Project/Area Number |
19500238
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Statistical science
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| Research Institution | Nagasaki University |
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Principal Investigator |
TSUYOSHI Nakamura Nagasaki University, 環境科学部, 教授 (80039586)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2007: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 医薬生物統計 / 移設可能性 / メタボリック症候群 / 多変量正規分布 / 放射線影響研究所 / コホート / リスク推定 / Transportable / Metabolic syndrome / 予測可性能 / 予測精度 / 正規変換 / 後ろ向きコホート研究 / 測定誤差モデル |
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| Research Abstract |
The validity of the diagnostic criteria for Metabolic Syndrome (MS) has been questioned since the syndrome was introduced. To verify their validity, the best strategy would be a cohort study. However, waist circumference (WC), which is necessary for the diagnosis of MS, was introduced to health examinations only recently. If a current regression model of WC could be transported to a previous sample, a cohort study using estimates of WC would be possible. We propose a sufficient condition for the transportability from a mathematical point of view. Using data from the Radiation Effect Research Foundation, we examined whether the proposed condition may be statistically confirmed in a real dataset. The regression model for weight, which is strongly associated with WC, was used to verify the validity of the condition. The relative risk of death from MS-related causes was obtained. The results indicated that the risk was lower with a greater WC.
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