Transitions between "internal states" in the brain viewed as quasi-attractors- A mathematical and neurodynamical approach

• Project/Area Number: 19500259
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Bioinformatics/Life informatics
• Research Institution: Kyoto Sangyo University
• Principal Investigator: FUJII Hiroshi Kyoto Sangyo University, コンピュータ理工学部, 教授 (90065839)
• Co-Investigator(Kenkyū-buntansha): TSUDA Ichiro 北海道大学, 電子科学研究所, 教授 (10207384)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2007: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: トップダウン注意 / 疑アトラクタ / 皮質の状態遷移 / GABA放出の前シナプス抑制 / ムスカリン様アセチルコリン受容体 / 皮質求心性アセチルコリン / マイネルト核 / レビ小体型認知症と幻覚 / トップダウン信号 / 心的イメージ / エピソード記憶 / 内部表現の再構築 / ムスカリン性シナプス前抑制 / ニコチン性脱分極 / アトラクターの過渡的構築 / 大脳皮質の状態遷移 / 知覚のトップダウン・メカニズム / 擬アトラクタ / 脱抑制による“局所アトラクタ"の安定化 / 海馬入力の皮質側の解釈 / 抑制性1層細胞 / 皮質2 / 3層錐体細胞の脱抑制 / 知覚、認知の脳内プロセス / 脳における状態遷移 / 大域的シンクロニー / 「注意」の不全 / 幻覚 / レビ小体型認知症

Research Abstract

We presented a scenario on the possible mechanism of cortical state transitions which occur associated with the arrival of top-down attention (s). This study would provide the basic framework for mathematical study and modeling of such cortical state transitions. We argue how the three physiological mechanisms including the corticopetal acetylcholine induce transient reconstruction of attractors, which simultaneously work in the layer 1 and 2/3 with top-down attentional glutamatergic spike volleys.

Research Products

• [Journal Article] Top-down Mechanism of Perception : A Scenario on the Role for Layer 1 and 2/3 Projections Viewed from Dynamical Systems Theory (2010)
  • Author(s): H.Fujii, K.Aihara, I.Tsuda
  • Journal Title: Proceedings of ICCN 2009(Springer Verlag) (to appear)
  • Peer Reviewed
• [Journal Article] Corticopetal Acetylcholine: Possible Scenarios on the Role for Dynamic Organization of Quasi-Attractors, in M. Ishikawa, et al.(Eds.) (2008)
  • Author(s): H. Fujii, K. Aihara, I. Tsuda
  • Journal Title: Neural Information Processing, Lecture Notes in Computer Science 4984 Pages: 170-178
  • Peer Reviewed
• [Journal Article] Corticopetal Acetylcholine: A Role in Attentional State Transitions and the Genesis of Quasi-Attractors During Perception, in R. Wang, et al., (Eds:) (2008)
  • Author(s): H. Fujii, K. Aihara, I. Tsuda
  • Journal Title: Advances in Cognitive Neurodynamics ICCN 2007 Pages: 251-255
  • Peer Reviewed
• [Journal Article] Corticopetal Acetylcholine : A Role in Attentional State Transitions and the Genesis of Ouasi-Attractors (2008)
  • Author(s): H. Fujii
  • Journal Title: R. Wang, et al. (eds. ), Advances in Cogni-tive Neurodynamics, Sprinser-Verlag Pages: 251-255
  • Peer Reviewed
• [Journal Article] Corticopetal Acetylcholine : Possible Scenarios on the Role for Dynamic Organization of Quasi-Attractors (2008)
  • Author(s): H. Fujii
  • Journal Title: Lecture Notes in Computer Science(LNCS), Springer-Verlag 4984 Pages: 170-178
  • Peer Reviewed
• [Journal Article] Chaos Reality in the Brain (2007)
  • Author(s): I. Tsuda, H. Fujii
  • Journal Title: J. of Integrative Neuroscience 6 Pages: 309-326
  • Peer Reviewed
• [Journal Article] Bifurcations in two-dimensional Hindmarsh-Rose type model (2007)
  • Author(s): S. Tsuji, T. Ueta, H. Kawakami, H. Fujii, K. Aihara
  • Journal Title: International Journal of Bifurcation and Chaos 17(3) Pages: 985-998
  • NAID: 120006501907
  • Peer Reviewed
• [Journal Article] Chaos Reality in the Brain (2007)
  • Author(s): I. Tsuda
  • Journal Title: J. Integrative Neuroscience 6 Pages: 309-326
  • Peer Reviewed
• [Journal Article] Bifurcations in two-dimensional Hindmarsh-Rose type model (2007)
  • Author(s): S. Tsuji
  • Journal Title: International Journal of Bifurcation and Chaos 17 Pages: 985-998
  • Peer Reviewed
• [Presentation] Top-down Mechanism of Perception: A Scenario on the Role for Top-down Layer 1 and 2/3 Projections from A Dynamical Systems View- Questions on Roles for Two Concurrent Flows of Signals: Corticopetal Acetylcholine and Top-down Glutamatergic Projections (2009)
  • Author(s): H. Fujii
  • Organizer: International Conference on Cognitive Neurodynamics ICCN 2009
  • Place of Presentation: at Hangzhou, China
• [Presentation] Top-down Mechanism of Perception:fromA Dynamical Systems View- Questions on Roles of Corticopetal Acetylcholine and Top-down Glutamatergic Projections on Layer 1 (2009)
  • Author(s): H. Fujii
  • Organizer: Dynamic Brain Forum 2009
  • Place of Presentation: at Atami, Japan
• [Presentation] Top-down Mechanism of Perception : A Scenario on the Role for Top-down Layer 1 and 2/3 Projections from A Dynamical Systems View-Questions on Roles for Two Concurrent Flows of Signals : Corticopetal Acetylcholine and Top-down Glutamatergic Projections (2009)
  • Author(s): H.Fujii
  • Organizer: International Conference on Cognitive Neuro-dynamics ICCN 2009
  • Place of Presentation: Hangzhou, China
• [Presentation] Top-down Mechanism of Perception-from A Dynamical Systems View (2009)
  • Author(s): Hiroshi FUJII
  • Organizer: Dynamic Brain Forum, 2009
  • Place of Presentation: 静岡県熱海市
• [Presentation] Nucleus Basalis of Meinert and Brain Dynamics in Cognition- Mysteries and Questions (2008)
  • Author(s): H. Fujii
  • Organizer: Workshop on Dynamical Circuits in the Brain
• [Presentation] Corticopetal Acetylcholine: A Role in Attentional State Transitions and the Genesis of Quasi-Attractors during Perception (2007)
  • Author(s): H. Fujii
  • Organizer: 1st International Conference on Cognitive Neuro-dynamics-ICCN2007
  • Place of Presentation: Changhai, China
  • Year and Date: 2007-11-19
• [Presentation] Corticopetal Acetylcholine: Possible Scenarios on the Role for Dynamic Organization of Quasi-Attractors (2007)
  • Author(s): H. Fujii
  • Organizer: 14th International Conference on Neural Information Processing-ICONIP 2007
  • Place of Presentation: 北九州市・北九州学術研究都市
  • Year and Date: 2007-11-16
• [Presentation] 『動力学から見た"脳"-知覚と意識への序論』 (2007)
  • Author(s): 藤井 宏
  • Organizer: 日本数学会平成19年度秋季総合分科会企画特別講演(招待)
  • Place of Presentation: 仙台市・東北大学
  • Year and Date: 2007-09-24
• [Presentation] Corticopetal Acetylcholine- Possible Scenarios on the Role for Dynamic Organization of Quasi-Attractors (2007)
  • Author(s): H. Fujii
  • Organizer: 14th International Conference on Neural Information Processing Towards an Integrated Approach to the Brain- Brain-Inspired Engineering and Brain Science
  • Place of Presentation: Kita-Kyushu, Japan
• [Presentation] Corticopetal Acetylcholine: A Role in Attentional State Transitions and the Genesis of Quasi-Attractors during Perception (2007)
  • Author(s): H. Fujii
  • Organizer: 1st International Conference on Cognitive Neurodynamics ICCN
  • Place of Presentation: Shanghai, China
• [Presentation] 動力学から見た"脳"-知覚と意識への序論 (2007)
  • Author(s): 藤井宏
  • Organizer: 日本数学会秋季総合分科会企画特別講演(招待講演)