Study of eggshell membrane : possibility to a scaffold in wound healing and biological material for an anti-adhesive membrane

• Project/Area Number: 19500409
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Biomedical engineering/Biological material science
• Research Institution: Tokyo Women's Medical University
• Principal Investigator: GOYA Nobuyuki Tokyo Women's Medical University, 医学部, 准教授 (40142492)
• Co-Investigator(Kenkyū-buntansha): 冨澤 康子 東京女子医科大学, 医学部, 助教 (00159047)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2007: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 卵 / 卵殻膜 / 創傷治癒 / 足場 / 癒着防止 / 材料 / 膜 / 血管新生 / 癒着 / 再生医学 / 外科 / 治療 / 創傷活巾

Research Abstract

卵の内側の薄皮を卵殻膜といい、過去において創傷被覆材として用いられていた。卵殻膜の創傷治癒における足場としての役割及び癒着防止膜としての医用材料への可能性を評価したところ、線維芽細胞も新生血管も膜には癒着せず、創部を"分離する"という意味では感染防止に役に立ち、創傷被覆材への応用の可能性が示唆された。卵殻膜の創傷被覆材に応用ならば、固定方法の選択は広がることが示唆された。

Research Products

• [Journal Article] Clinical outcome ofhigh-grade non-muscle-invasive bladdercancer (2009)
  • Author(s): Iida S, Kondo T, Kobayashi H, Hashimoto Y, Goya N, Tanabe K
  • Journal Title: a long-term single center experience.Int J Urol 16(3)
  • Peer Reviewed
• [Journal Article] Microcirculatory responses toacupuncture stimulation and phototherapy (2009)
  • Author(s): Komori M, Takada K, Tomizawa Y,Nishiyama K, Kondo I, Kawamata M, Ozaki M
  • Journal Title: Anesth Analg 108(2) Pages: 635-640
  • Peer Reviewed
• [Journal Article] Intravascularforeign bodies : danger of unretrievedfragmented medical devices (2009)
  • Author(s): Tateishi M, Tomizawa Y
  • Journal Title: J Artif Organs (in press) Pages: 12-12
  • Peer Reviewed
• [Journal Article] Certifiedperfusionists at core institution accredited bythe Japanese Board of CardiovascularSurgery (2009)
  • Author(s): Tomizawa Y, Momose N
  • Journal Title: J Artif Organs (in press)
  • Peer Reviewed
• [Journal Article] 国内外胸部心臓血管外科系学術雑誌のh-indexを用いた評価 (2009)
  • Author(s): 冨澤康子
  • Journal Title: 日心臓血管外会誌 38(1) Pages: 11-16
  • NAID: 110007028534
  • Peer Reviewed
• [Journal Article] A case of renal cellcarcinoma with intrahepatic vena cavaltumor thrombus successfully managed bysurgery in a long-term chronic hemodialysispatient with liver cirrhosis (2009)
  • Author(s): Iida S, Kondo T, Tomita E, Kouchi Y, GoyaN, Ito F, Tanabe K
  • Journal Title: Hinyokika Kiyo 54(3) Pages: 229-234
  • Peer Reviewed
• [Journal Article] Intravascular foreign bodies : danger of unretrieved fragmented medical devices. (2009)
  • Author(s): Tateishi M. Tomizawa Y
  • Journal Title: J Artif Organs 12(In press)
  • NAID: 10025350825
  • Peer Reviewed
• [Journal Article] Incident-simulating device with wirelesscontrol for extracorporeal circulation crisismanagement drills (2008)
  • Author(s): Momose N, Tomizawa Y
  • Journal Title: Perfusion 23(1) Pages: 17-21
  • Peer Reviewed
• [Journal Article] Quantitativeevaluation of hand cranking a roller pump ina crisis management drill (2008)
  • Author(s): Tomizawa Y, Tokumine A, Ninomiya S,Momose N, Matayoshi T
  • Journal Title: J Artif Organs 11(3) Pages: 117-122
  • Peer Reviewed
• [Journal Article] 医学部における女性研究者のh-index と科学研究補助金連続取得 (2008)
  • Author(s): 冨澤康子
  • Journal Title: 東女医大誌 78(8-9) Pages: 443-447
  • NAID: 110007524746
  • Peer Reviewed
• [Journal Article] 心臓血管領域 人工心肺を用いた体外循環のリスクマネジメント (2008)
  • Author(s): 冨澤康子
  • Journal Title: 胸部外科 61(8) Pages: 636-639
  • Peer Reviewed
• [Journal Article] 誤診を防ぐ護身術 陰茎折症の対策 (2008)
  • Author(s): 合谷信行
  • Journal Title: 泌尿器外科 21(5) Pages: 720-721
  • Peer Reviewed
• [Journal Article] 医学部における女性研究者のh-indexと科学研究補助連続取得 (2008)
  • Author(s): 冨澤康子
  • Journal Title: 女子医大学会雑誌 78 Pages: 443-447
  • Peer Reviewed
• [Journal Article] Effects of directinjection of dehydrated ethanol on PC3human prostate cancer cells in nude mice (2007)
  • Author(s): Goya N, Koga S, Tomizawa Y, Onitsuka S,Yamaguchi Y, Toma H
  • Journal Title: preliminary study. Int J Urol 14(8) Pages: 760-763
  • Peer Reviewed
• [Journal Article] Toma H. Local injection of asustained-release antiandrogen formulationinto a target prostatic site (2007)
  • Author(s): Goya N, Gotanda K, Sasaki T, Okada M,Tomizawa Y
  • Journal Title: an experimentalstudy. BJU Int 99(1) Pages: 202-206
  • Peer Reviewed
• [Journal Article] Permissive range of hypercapnia forimproved peripheral microcirculation andcardiac output in rabbits (2007)
  • Author(s): Komori M, Takada K, Tomizawa Y,Nishiyama K, Kawamata M, Ozaki M
  • Journal Title: Crit Care Med 35(9) Pages: 2171-5
  • Peer Reviewed
• [Journal Article] Development of an educationalsimulator system, ECCSIM-Lite, for theacquisition of basic perfusion techniques andevaluation (2007)
  • Author(s): Ninomiya S, Tokumine A, Yasuda T,Tomizawa Y
  • Journal Title: J Artif Organs 10(4) Pages: 201-205
  • Peer Reviewed
• [Journal Article] Corrosion of PureTitanium Sternal Wire (2007)
  • Author(s): Tomizawa Y, Hanawa T
  • Journal Title: Ann Thorac Surg 84(3) Pages: 1012-1014
  • Peer Reviewed
• [Journal Article] Certifiedperfusionists in Japan (2007)
  • Author(s): Tomizawa Y, Momose N
  • Journal Title: J Artif Organs 10(2) Pages: 122-123
  • Peer Reviewed
• [Journal Article] 装置と方法 軽量で開閉可能な家兎耳介観察窓の開発 (2007)
  • Author(s): 佐藤章, 冨澤康子, 小森万希子, 高田勝美
  • Journal Title: 呼吸と循環 55(3) Pages: 359-362
  • Peer Reviewed
• [Journal Article] Local injection of a sustained-release antiandrogen formulation into a target prostatic site: an experimental study. (2007)
  • Author(s): Goya N, Gotanda K., et. al.
  • Journal Title: BJU Int 99 Pages: 202-206
  • Peer Reviewed
• [Journal Article] Effects of direct injection of dehydrated ethanol on PC3 human prostate cancer cells in nude mice: Preliminary study. (2007)
  • Author(s): Goya N, Koga S., et. al.
  • Journal Title: Int J Urol, 14 Pages: 760-763
  • NAID: 10019530366
  • Peer Reviewed
• [Journal Article] 軽量で開閉可能な家兎耳介観察窓の開発 (2007)
  • Author(s): 佐藤章、冨澤康子、他
  • Journal Title: 呼吸と循環 55 Pages: 359-362
  • Peer Reviewed
• [Presentation] 安全教育を目的とした医療用Serious Game「人工心肺の安全な操作」の開発 (2008)
  • Author(s): 冨澤康子, 他
  • Organizer: 第108回日本外科学会定期学術集会
  • Place of Presentation: 長崎
• [Presentation] Toma H. Local injection ofsustained-release antiandrogen formulationinto a targeted prostatic site : an experimentalstudy (2007)
  • Author(s): Goya N, Gotanda K, Sasaki T, Okada M,Tomizawa Y
  • Organizer: AUA Anuual Meeting
  • Place of Presentation: Los Angels, CA, USA
  • Year and Date: 2007-05-22
• [Presentation] Local injection of sustained-release antiandrogen formulation into a target prostatic site: an experimental study (2007)
  • Author(s): Goya N, Tomizawa Y
  • Organizer: AUA Annual Meeting
  • Place of Presentation: CA
  • Year and Date: 2007-05-22
• [Book] EndNote100の裏ワザ. 東京 (2009)
  • Author(s): 冨澤康子
  • Total Pages: 239
  • Publisher: 秀潤社
• [Book] 人工臓器 第24回教育セミナー (2008)
  • Author(s): 冨澤康子
  • Total Pages: 127
  • Publisher: 日本人工臓器学会