Noninvasive evaluation of the carotid plaque characteristics based on regional strain measurement using two-dimensional speckle tracking imaging
| Project/Area Number |
19500412
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Medical systems
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| Research Institution | Hokkaido University |
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Principal Investigator |
MIKAMI Taisei Hokkaido University, 大学院・保健科学研究院, 教授 (90250456)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 超音波医科学 / 血管病態学 / 粥状動脈硬化 / 虚血性脳血管障害 / 頚動脈エコー / 二次元スペックルトラッキング |
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| Research Abstract |
There has been no established method to measure distensibility of a specific area of medium-sized artery wall. We attempted to measure segmental strain of the carotid artery wall using ultrasonic 2-dimensional speckle tracking method and investigate the relationship to the local atherosclerotic lesions. Two-hundred carotid arteries of 100 patients with ischemic cerebrovascular disease were studied and the far wall of the common carotid artery in long-axis B-mode image was divided into 5 segments. In each segment, the longitudinal and radial peak strain and intima-media thickness (IMT) were measured. Strain measurements were possible in 885 of the 1000 segments (88.5%), and the radial peak strain was significantly reduced in the segments with plaque (IMT>=1.2mm, -3.53+/-2.79%) than those without (-4.67+/-2.85%, p<0.0001). Two-dimensional speckle tracking imaging may be useful to measure regional distensibility of the carotid atherosclerotic lesions.
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Report
(4 results)
Research Products
(18 results)
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[Journal Article] Right ventricular diastolic dysfunction in patients with left ventricular hypertrophy : analysis of right ventricular myocardial relaxation using two-dimensional speckle tracking imaging2009
Author(s)
Kaga S, Mikami T, Onozuka H, Omotehara S, Abe A, Yamada S, Okada M, Komatsu H, Inoue M, Yokoyama S, Nishida M, Shimizu C, Matsuno K, Tsutsui H
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Journal Title
J of Echocardiogr Vol. 7
Pages: 25-33
NAID
Related Report
Peer Reviewed
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[Journal Article] Prevalence and clinical significance of spontaneous echo contrast within the carotid artery in patients with ischemic cerebrovascular disease2007
Author(s)
Onozuka H, Muraki M, Mikami T, Yoshimoto T, Yoshizumi T, Kitaguchi M, Sugawara T, Tokuda K, Kaneko S, Kashiwaba T, Yamada S, Tsutsui H, Kitabatake A
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Journal Title
J Ultrasound Med Vol 26
Pages: 169-177
Related Report
Peer Reviewed
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[Presentation] Clinical Significance of Bizarre Pulsatile Motion of Carotid Artery Plaque Visualized by Carotid Sonography2009
Author(s)
Mikami T, Muraki M, Onozuka H, Yoshimoto T, Kitaguchi M, Sugawara T, Yoshizumi T, Shirasaki T, Fujimoto S, Tokuda K, Kaneko S, Kashiwaba T, Abe A, Yamada S, Tsutsui H
Organizer
17th Asian Pacific Congrees of Cardiology
Place of Presentation
Kyoto, Japan
Year and Date
2009-05-20
Related Report
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[Presentation] 二次元スペックルトラッキング法による総頸動脈の局所壁伸展性評価の試み2009
Author(s)
阿部歩, 三神大世, 小野塚久夫, 岩井孝仁, 大久保真理亜, 村木睦子, 吉本哲之, 金子貞男, 柏葉武, 山田聡, 筒井裕之
Organizer
第73回日本循環器学会総会学術集会
Place of Presentation
大阪
Year and Date
2009-03-22
Related Report
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[Presentation] 頸動脈エコーによるプラーク局所の不自然な動きの評価とその臨床的意義2008
Author(s)
村木睦子, 三神大世, 吉本哲之, 北口真弓, 白坂智英, 藤本真, 善積威, 菅原智子, 徳田耕一, 金子貞男, 柏葉武, 阿部歩, 小野塚久夫, 山田聡, 筒井裕之
Organizer
日本超音波医学会第81回学術集会
Place of Presentation
神戸
Year and Date
2008-05-24
Related Report
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[Presentation] 左室肥大における右室機能障害の機序 : 2Dスペックルトラッキング法による検討2008
Author(s)
加賀早苗, 三神大世, 小野塚久夫, 井上真美子, 横山しのぶ, 清水力, 松野一彦, 小松博史, 岡田昌子, 山田聡, 筒井裕之
Organizer
第19回日本心エコー図学会学術集会
Place of Presentation
神戸
Year and Date
2008-04-11
Related Report
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