Study of sentinel node detection method using contrast-enhanced ultrasonography with second generation of ultrasound contrast agent in malignant tumor
Project/Area Number |
19500424
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Medical systems
|
Research Institution | Jichi Medical University |
Principal Investigator |
OMOTO Kiyoka Jichi Medical University, 医学部, 准教授 (90306118)
|
Co-Investigator(Kenkyū-buntansha) |
TANIGUCHI Nobuyuki 自治医科大学, 医学部, 教授 (10245053)
HOZUMI Yasuo 自治医科大学, 医学部, 准教授 (50260831)
|
Project Period (FY) |
2007 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
Keywords | 第2世代超音波造影剤 / ソナゾイド / センチネルリンパ節 / 乳癌 / 超音波造影法 / 超音波造影剤 / 造影超音波画像 / 臨床研究 / 次世代超音波造影剤 / 悪性腫瘍 / 腋窩リンパ節郭清 |
Research Abstract |
This study aimed to evaluate the usefulness of sentinel lymph node (SLN) detection in breast cancer using contrast-enhanced ultrasonography with Sonazoid. More than 100 breast cancer patients were examined in our hospital. After 2 ml of Sonazoid was injected subareolarly, the axillary area was observed transdermally using ultrasonography with linear transducer. A contrast-enhanced SLN was seen within 5 min, and its detection rate was more than 80%. Moreover the SLN detection rate was compared with that of other methods and resected SLNs were evaluated pathologically. It is suggested that our new method is clinically useful for sentinel node identification.
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Report
(4 results)
Research Products
(11 results)
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[Journal Article] Sentinel node detection method using contrast-enhanced ultra-sonography with Sonazoid in breast cancer: Preliminary clinical study2009
Author(s)
Omoto K, Matsunaga H, Take N, Hozumi Y, Takehara M, Omoto Y, Shiozawa M, Mizunuma H, Harashi-ma H, Taniguchi N, Kawano M
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Journal Title
Ultrasound Med Biol 35
Pages: 1249-1256
Related Report
Peer Reviewed
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[Journal Article] Sentinel node detection method using contrast-enhanced ultrasonography with Sonazoid in breast cancer : Preliminary clinical study2009
Author(s)
Omoto K, Matsunaga H, Take N, Hozumi Y, Takehara M, Omoto Y, Shiozawa M, Mizunuma H, Harashima H, Taniguchi N, Kawano M
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Journal Title
Ultrasound Med Biol 35
Pages: 1249-1256
Related Report
Peer Reviewed
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