Basic study that examining immune regulatory effect of soy isoflavones.
| Project/Area Number |
19500685
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | The University of Tokushima |
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Principal Investigator |
SAKAI Tohru The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 教授 (40274196)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | イソフラボン / 免疫 / 大腸炎 / 大豆 / エクオール / サイトカイン / ゲニステイン / ダイゼイン |
|---|
| Research Abstract |
Soy foods have been consumed for centuries in Asian countries. Human clinical and epidemiological studies have revealed many potential benefits of intake of soy products. In this study, we therefore investigated the effects of equol on ovalbumin (OVA)-speficic T cell and B cell responses in BALB/c mice. Mice that had been treated with 20mg/kg equol showed a significantly higher level of OVA-specifc IgE than that in control mice. Furthermore, equol perpetrated DSS-induced colitis in BALB/c mice.
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Report
(4 results)
Research Products
(19 results)
