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Effects of rice protein on insulin response and carbohydrate metabolism in Goto-Kakizaki (GK) rats

Research Project

Project/Area Number 19500706
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Eating habits, studies on eating habits
Research InstitutionNiigata Women's College

Principal Investigator

WATANABE Reiko  Niigata Women's College, 生活科学科, 教授 (70141348)

Co-Investigator(Kenkyū-buntansha) 門脇 基二  新潟大学, 自然科学系, 教授 (90126029)
Co-Investigator(Renkei-kenkyūsha) KADOWAKI Motoni  新潟大学, 自然科学系, 教授 (90126029)
Research Collaborator KUBOTA Masatoshi  新潟大学, 大学院・自然科学研究科・生命・食料科学専攻, 後期課程3年
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords米タンパク質 / 糖代謝 / インスリン / 血糖値 / 成熟期および2型糖尿病ラット / 2型糖尿病モデルラット / 成熟期ラット
Research Abstract

「こしひかり」と「春陽」由来の米胚乳タンパク質を、成熟期ラットや自然発症の非肥満2型糖尿病モデルラットに給与して長期の飼養試験(対照はカゼイン食)を実施した。両米タンパク質摂取群の空腹時血糖値やインスリン値に低下傾向がみられ、血中アデイポネクチン濃度は有意に上昇し、カゼインに比べてインスリン応答や糖代謝調節維持に有効である可能性が強く示唆された。今後、ヒト試験をふまえて社会的貢献が大いに期待できる。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (23 results)

All 2009 2008 2007 Other

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (18 results) Remarks (1 results)

  • [Journal Article] Superiority of alkali-extracted rice protein in bioavailability to starch degraded rice protein comes from the digestion of prolamin in growing rats2009

    • Author(s)
      Takehisa Kumagai,Reiko Watanabe,Mariko Saito,Toshiyuki Watanabe,Masatoshi Kubota and Motoni Kadowaki
    • Journal Title

      J Nutr Sci Vitaminol 55

      Pages: 170-177

    • NAID

      10025970960

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Superiority of Alkali-extracted Rice Protein in Bioavailability to Starch Degraded Rice Protein Comes from the Digestion of Prolamin in Growing Rats.2009

    • Author(s)
      Takehisa Kumagai
    • Journal Title

      J Nutr Sci Vitaminol 55

      Pages: 170-177

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 新規食品素材としてのコメタンパク質とその生理機能2008

    • Author(s)
      門脇基二,久保田真敏,増村威宏,熊谷武久,渡邊令子
    • Journal Title

      New Food Industry Vol. 52, No.12

      Pages: 37-42

    • NAID

      40016352826

    • Related Report
      2008 Final Research Report
  • [Journal Article] 新規食品素材としてのコメクンパク質とその生理機能2008

    • Author(s)
      門脇基二
    • Journal Title

      New Food Industry 52(12)

      Pages: 37-42

    • Related Report
      2008 Annual Research Report
  • [Presentation] 炊飯処理が米タンパク質の In vivo 消化性に与える影響2008

    • Author(s)
      久保田真敏
    • Organizer
      日本アミノ酸学会
    • Place of Presentation
      東京大学鉄門-講堂
    • Year and Date
      2008-10-02
    • Related Report
      2008 Final Research Report
  • [Presentation] 炊飯処理が米タンパク質のIn vivo消化性に与える影響2008

    • Author(s)
      久保田真敏
    • Organizer
      日本アミノ酸学会
    • Place of Presentation
      東京大学鉄門講堂
    • Year and Date
      2008-10-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] 米ペプチドの効率的製法とその摂取が血漿および肝臓脂質に及ぼす影響2008

    • Author(s)
      渡邊令子
    • Organizer
      日本栄養・食糧学会
    • Place of Presentation
      女子栄養大学
    • Year and Date
      2008-05-04
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 米タンパク質プロラミンの消化性に対する炊飯処理の影響2008

    • Author(s)
      久保田真敏
    • Organizer
      日本栄養・食糧学会
    • Place of Presentation
      女子栄養大学
    • Year and Date
      2008-05-04
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Bioavailability of alkaline extracted rice protein in rats and its effects on serum albumin and cholesterol levels in Japanese elderly2008

    • Author(s)
      Reiko Watanabe
    • Organizer
      2^<nd> International Symposium on Rice and Disease Prevention
    • Place of Presentation
      Wakayama Prefectural Culture Hall, Wakayama, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] Effects of cooking process on the in vivo digestibility of rice prolamin in rats2008

    • Author(s)
      Masatoshi Kubota
    • Organizer
      2^<nd> International Sym- posium on Rice and Disease Prevention
    • Place of Presentation
      Wakayama Prefectural Culture Hall, Wakayama, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] Ohno,Search for new functions of rice protein and rice bran protein by DNA microarray technique2008

    • Author(s)
      Chieko Ohno
    • Organizer
      2^<nd> International Sym- posium on Rice and Disease Prevention
    • Place of Presentation
      Wakayama Prefectural Culture Hall, Wakayama, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] Effects of Cooking Process on the In vivo Digestibility of Rice Prolamin in Rats.2008

    • Author(s)
      Masatoshi Kubota
    • Organizer
      2^<nd> International Symposium on Rice and Disease Prevention
    • Place of Presentation
      和歌山県民文化会館
    • Related Report
      2008 Annual Research Report
  • [Presentation] Bioavailability of Alkaline Extracted Rice Protein in Rats and Its Effects on Serum Albumin and Cholesterol Levels in Japanese Elderly.2008

    • Author(s)
      Reiko Watanabe
    • Organizer
      2^<nd> International Symposium on Rice and Disease Prevention
    • Place of Presentation
      和歌山県民文化会館
    • Related Report
      2008 Annual Research Report
  • [Presentation] Search for New Functions of Rice Protein and Rice Bran Protein by DNA Microarray Technique.2008

    • Author(s)
      Chieko Ohno
    • Organizer
      2^<nd> International Symposium on Rice and Disease Prevention
    • Place of Presentation
      和歌山県民文化会館
    • Related Report
      2008 Annual Research Report
  • [Presentation] 米タンパク質プロラミンの顆粒構造とIn vivo 消化性2007

    • Author(s)
      久保田真敏
    • Organizer
      日本アミノ酸学会
    • Place of Presentation
      東京大学山上会館
    • Year and Date
      2007-11-22
    • Related Report
      2008 Final Research Report
  • [Presentation] 米タンパク質プロラミンの顆粒構造とIn vivo消化性2007

    • Author(s)
      久保田 真敏
    • Organizer
      日本アミノ酸学会
    • Place of Presentation
      東京大学山上会館
    • Year and Date
      2007-11-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] Difference in manufacturing process of rice protein affects its digestibility in gastrointesti- nal tract of rats2007

    • Author(s)
      Masatoshi Kubota
    • Organizer
      10th Asian Congress of Nutrition
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2007-09-12
    • Related Report
      2008 Final Research Report
  • [Presentation] Effects of rice protein prepared by different methods on In vivo digestibility and growth in rats2007

    • Author(s)
      Reiko Watanabe
    • Organizer
      10th Asian Congress of Nutrition
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2007-09-12
    • Related Report
      2008 Final Research Report
  • [Presentation] Influence of alkaline extracted rice protein on serum albumin and cholesterol levels in community- dwelling older Japanese adults2007

    • Author(s)
      Motoni Kadowaki
    • Organizer
      10th Asian Congress of Nutrition
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2007-09-12
    • Related Report
      2008 Final Research Report
  • [Presentation] Difference in Manufacturing Process of Rice Protein Affects Its Digestibility in Gastrointestinal Tract of Rats2007

    • Author(s)
      Masatoshi Kubota
    • Organizer
      10th Asian Congress of Nutrition
    • Place of Presentation
      Taipei,TAIWAN
    • Year and Date
      2007-09-12
    • Related Report
      2007 Annual Research Report
  • [Presentation] Effects of Rice Protein Prepared by Different Methods on In Vivo Digestibility and Growth in Rats2007

    • Author(s)
      Reiko Watanabe
    • Organizer
      10th Asian Congress of Nutrition
    • Place of Presentation
      Taipei,TAIWAN
    • Year and Date
      2007-09-12
    • Related Report
      2007 Annual Research Report
  • [Presentation] Influence of Alkaline Extracted Rice Protein on Serum Albumin And Cholesterol Levels in Community-dwelling Older Japanese Adults2007

    • Author(s)
      Motoni Kadowaki
    • Organizer
      10th Asian Congress of Nutrition
    • Place of Presentation
      Taipei,TAIWAN
    • Year and Date
      2007-09-12
    • Related Report
      2007 Annual Research Report
  • [Remarks] 2008年11月29日に、研究者から一般市民までの幅広い層を対象として「食と健康の新潟国際フォーラム」が開催された。その中で、「コメの機能、おいしさ、そして健康」をテーマとして国際会議が企画され、米タンパク質に関する一連の研究成果の一部(雑誌論文に掲載済み)を紹介した。

    • Related Report
      2008 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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