Design of Novel Stereoisomers by Using Narrow Space in π-System Rigid Frameworks
| Project/Area Number |
19550054
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Organic chemistry
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| Research Institution | Okayama University of Science |
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Principal Investigator |
TOYOTA Shinji Okayama University of Science, 理学部, 教授 (80207646)
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| Co-Investigator(Renkei-kenkyūsha) |
IWANAGA Tetsuo 岡山理科大学, 理学部, 助教 (40454805)
WAKAMATSU Kan 岡山理科大学, 理学部, 准教授 (60271425)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 立体異性体 / パイ系化合物 / 分子設計 / 構造有機化学 / 剛直環構造 / アセチレン / アントラセン / カップリング反応 / キラル / 分子構造 / 立体障害 / 自己会合 / X線構造解析 |
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| Research Abstract |
We designed rigid cyclic compounds consisting of anthracene units and acetylene (or diacetylene) linkers as new π-conjugated compounds. Substituents were introduced at inner congested positions, and we isolated some novel stereoisomers (diastereomers and enantiomers) based on the steric hindrance between the ring framework and the intraannular substituents. The structures and dynamic behavior of these isomers were investigated by X-ray analysis, NMR spectra, and DFT calculations. We propose a new concept of stereochemistry through this molecular design.
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Report
(4 results)
Research Products
(38 results)
