Development surface plasmon sensor with multi channel and measurement of residual antibiotics

• Project/Area Number: 19550076
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Analytical chemistry
• Research Institution: Muroran Institute of Technology
• Principal Investigator: KANEKI Noriaki Muroran Institute of Technology, 大学院・工学研究科, 教授 (40125373)
• Co-Investigator(Kenkyū-buntansha): SHIMADA Kouji 室蘭工業大学, 大学院・工学研究科, 准教授 (90178939)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2007: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 表面プラズモン共鳴 / バイオセンサ / 携帯型 / 残留抗生物質

Research Abstract

An analytical method using surface plasmon resonance (SPR) is one of the most powerful methods for evaluating biomolecule interaction. Conventional SPR sensor, however, were not suitable for on-site analysis because of the size, weight and cost of the instruments. In this study, we attempted to develop a new portable-type SPR sensor with multi detection points for on-site analysis. The SPR sensor had the new optical system which consisted of a LD light, a multi-beam splitter, a sensor prism and a PD array. The sensor was able to detect residual antibiotics in milk.

Research Products

• [Journal Article] Development of Portable Surface Plasmon Resonance Sensor with Multi Detection Points (2007)
  • Author(s): H. Nakajima, K. Furui, Y. Li, J. Ren, N. Soh, K. Nakano, A. Hemmi, Y. Asano, K. Uchiyama, N. Kaneki, T. Imato
  • Journal Title: Proceedings of the μTAS 2 Pages: 1053-1055
• [Presentation] Surface Plasmon Resonance Sensor with Multi Detection Points and Its Application to Simultaneous Immunoassay for IgA and IgG (2008)
  • Author(s): A. Hemmi, K. Furui, H. Nakajima, N. Soh, K. Nakano, Y. Asano, K. Uchiyama, N. Kaneki, T. Imato
  • Organizer: The 12th International Meeting on Chemical Sensors
  • Place of Presentation: USA
  • Year and Date: 2008-07-15
• [Presentation] On-Chip Multi-Immunoassay Using a Portable Multi-Channel Surface Plasmon Resonance Sensor and a Micro Sensor Chip Prepared by Photochemical Patterning Method (2008)
  • Author(s): H. Nakajima, A. Hemmi, K. Furui, N. Soh, K. Nakano, Y. Asano, K. Uchiyama, N. Kaneki, T. Imato
  • Organizer: Pittsburgh Conference 2008
  • Place of Presentation: USA
  • Year and Date: 2008-03-05
• [Presentation] 多成分同時測定のためのポータブルマルチチャンネル表面プラズモン共鳴センサと光架橋反応を用いたセンサチップ内への位置選択的タンパク質固定化法の開発 (2007)
  • Author(s): 古井孝志, 中嶋秀, 宗伸明, 中野幸二, 辺見彰秀, 浅野泰一, 内山一美, 金木則明, 今任稔彦
  • Organizer: 第16回化学とマイクロ・ナノシステム研究会
  • Place of Presentation: つくば
  • Year and Date: 2007-10-30
• [Presentation] Development of Portable Surface Plasmon Resonance Sensor with Multi Detection Points (2007)
  • Author(s): H. Nakajima, K. Furui, Y. Li, J. Ren, N. Soh, K. Nakano, A. Hemmi, Y. Asano, K. Uchiyama, N. Kaneki, T. Imato
  • Organizer: μTAS 2007
  • Place of Presentation: France
  • Year and Date: 2007-10-09
• [Presentation] Application of Portable Surface Plasmon Resonance Sensor with Multi Detection Points to Immunoassay Using Sensor Chip Prepared by Photochemical Immobilization Method (2007)
  • Author(s): K. Furui, H. Nakajima, A. Hemmi, N. Soh, K. Nakano, Y. Asano, K. Uchiyama, N. Kaneki, T. Imato
  • Organizer: Tokyo Conference 2007, Asia Young Analytical Chemist Session
  • Place of Presentation: Tokyo
  • Year and Date: 2007-08-30
• [Presentation] ポータブル型マルチポイント表面プラズモン共鳴センサの開発 (2007)
  • Author(s): 古井孝志, 中嶋秀, 李岩, 任聚杰, 宗伸明, 中野幸二, 辺見彰秀, 浅野泰一, 内山一美, 金木則明, 今任稔彦
  • Organizer: 日本分析化学会第68回分析化学討論会
  • Place of Presentation: 宇都宮
  • Year and Date: 2007-05-20
• [Presentation] Development of Portable Surface Plasmon Resonance Sensor with Multi Detection Points (2007)
  • Author(s): A. Hemmi, K. Furui, H. Nakajima, Y. Li, J. Ren, N. Soh, K. Nakano, Y. Asano, K. Uchiyama, N. Kaneki, T. Imato
  • Organizer: Pittsburgh Conference
  • Place of Presentation: USA
  • Year and Date: 2007-02-27