Development and Application of Highly Chemoselective Organic Reductants
| Project/Area Number |
19550108
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Okayama University |
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Principal Investigator |
KUROBOSHI Manabu Okayama University, 大学院・自然科学研究科, 准教授 (30242316)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Keywords | ビオロゲン / 有機還元剤 / 電解還元 / ハロゲン化アリール / 還元的カップリング / ビアリール / イオン液体 / 水 / 有機電解 / 炭素-炭素結合形成 / パラジウム / カップリング反応 / Pd触媒 / 芳香族ハロゲン化物 / パラジウム触媒 / 還元的二量化 |
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| Research Abstract |
Several viologen derivatives (1,1'-disubstituted 4,4'-bipyridynium, V^<2+>) were synthesized, and their electrochemical behavior was studied to reveal that 1) two one-electron reduction processes occurred on V2^+ to give V^<+・> and V^0, stepwise, and 2) V^0s worked as organic reductants compatible to zinc. V^0 were generated by electroreduction of V^<2+>, and promoted Pd-catalyzed reductive coupling of aryl halides to give the corresponding biaryls. By proper choice of substituents on N of V^<2+>, V^0 could be used in several media such as usual organic solvents, ionic liquids, and water. Moreover, electroreduction of N-substituted pyridinium derivatives also gave organic reductants.
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Report
(4 results)
Research Products
(40 results)
