| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
A new method for the selective introduction of a substituent to inositol was developed by its solubilization in special solvents. The method realized one-step synthesis of a desired one or two substituted inositol derivative, which is required five steps at least to prepare in usual manner. We designed and made some derivatives to explore a biologically active and surface-active materials. The problematic solvents used here directed us to develop a new method for the synthesis of 3-ketoamide, and a tin-mediated substitution reaction.
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