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Study on Risk Diagnoses and Endovascular Therapy for Aneurysms

Research Project

Project/Area Number 19560160
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Fluid engineering
Research InstitutionTokyo University of Agriculture and Technology

Principal Investigator

TAKAKURA Yoko  Tokyo University of Agriculture and Technology, 大学院・共生科学技術研究院, 助教 (10262239)

Co-Investigator(Kenkyū-buntansha) 新井 紀夫  東京農工大学, 大学院・共生科学技術研究院, 教授 (20126288)
小西 善史  杏林大学, 保健学部, 教授 (10175333)
深作 和明  理化学研究所, 生体力学シミュレーション特別研究ユニット, 客員主管研究員 (80283266)
Co-Investigator(Renkei-kenkyūsha) ARAI Norio  東京農工大学, 大学院・共生科学技術研究院, 教授 (20126288)
KONISHI Yoshifumi  杏林大学, 保健学部, 教授 (10175333)
FUKASAKU Kazuaki  理化学研究所, 生体力学シミュレーション特別研究ユニット, 客員主管研究員 (80283266)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Keywordsバイオ流体力学 / 動脈瘤 / 血管内治療 / ステント / 流れ適合ステント / カテーテル / 危険予知 / 安全性 / 瘤の発生・成長 / 体外実験 / 数値計算 / PIV / せん断応力
Research Abstract

動脈瘤の危険予知と血管内治療に関し,流体力学者の視点を中心に据えながら体外実験と数値計算を行いデータを蓄積した.主な研究成果は,(1) 分岐脳動脈瘤の発生・成長過程についての仮説を組み立て,(2) 分岐脳動脈瘤の破裂の危険性について論じた. さらに(3) ステント特性の評価法を提示し,(4) 効果的なステントの設計として流れ適合ステントを提示した.最後に(5) 血管内治療の安全性をめざしてステント装着,カテーテル挿入時の安全指針についても言及した.

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (21 results)

All 2009 2008 2007 Other

All Journal Article (11 results) (of which Peer Reviewed: 11 results) Presentation (9 results) Remarks (1 results)

  • [Journal Article] 脳動脈瘤の分岐部血流評価2008

    • Author(s)
      小西善史, 塩川芳昭, 深作和明, 竹内昌孝, 新井紀夫, 高倉葉子, 尾棹敦
    • Journal Title

      In vitro study

      Pages: 311-316

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characteristic Flow Phenomena on a Tee-Branch Pipe2008

    • Author(s)
      Atsushi OSAO, Yoko TAKAKURA, Norio ARAI
    • Journal Title

      Journal of Visualization Vol.11, No.4

      Pages: 283-284

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Numerical Simulation of Flows in a Pipe with an Aneurysmal Sac (Effects of Aneurysmal Models and Stents)2008

    • Author(s)
      Gulbahar, W., Kobori, T., Takakura,Y., Arai, N., Konishi, Y., and Fukasaku, K.
    • Journal Title

      Advanced Materials Research Vols.33-37

      Pages: 1025-1030

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Numerical Study on Flow-Adaptive Stents2008

    • Author(s)
      Takakura, Y., Gulbahar, W., Arai, N., Konishi, Y., and Fukasaku, K.
    • Journal Title

      Stents," Advanced Materials Research Vols.33-37

      Pages: 1031-1036

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] In vitro Study on Branch Flows with a Cerebral Aneurysm2008

    • Author(s)
      Osao, A., Gulbahar W., Takakura,Y., Arai, N., Konishi, Y., and Fukasaku,K.
    • Journal Title

      Advanced Materials Research Vols.33-37

      Pages: 1037-1042

    • NAID

      110008459994

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 動脈瘤モデルを有する管内流れとステント特性2008

    • Author(s)
      高倉葉子, 小堀達也, 新井紀夫, 小西善史, 深作和明, 菊池伸匡
    • Journal Title

      日本機械学会論文集 74巻737号B編

      Pages: 16-24

    • NAID

      110006571247

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characteristic Flow Phenomena on a Tee-Branch Pipe2008

    • Author(s)
      Atsushi OSAO, Yoko TAKAKURA, Norio ARAI
    • Journal Title

      Journal of Visualization

      Volume: Vol.11No.4 Pages: 283-284

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 動脈瘤モデルを有する管内流れとステント特性2008

    • Author(s)
      高倉 葉子, 新井紀夫, 小西善史, 深作和明, 他
    • Journal Title

      日本機械学会論文集 74巻737号B編

      Pages: 16-24

    • NAID

      110006571247

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Numerical Simulation of Flows in a Pipe with an Aneurysmal Sac (Effects of Aneurysmal Models and Stents)2008

    • Author(s)
      Takakura, Y., Arai, N., Konishi, Y., and Fukasaku, K., et. al.
    • Journal Title

      Advanced Materials Research Vols.33-37

      Pages: 1025-1030

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Numerical Study on Flow-Adaptive Stents2008

    • Author(s)
      Takakura, Y., Arai, N., Konishi, Y., and Fukasaku, K., et. al.
    • Journal Title

      Advanced Materials Research Vols.33-37

      Pages: 1031-1036

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vitro Study on Branch Flows with a Cerebral Aneurysm2008

    • Author(s)
      Takakura, Y., Arai, N., Konishi, Y., and Fukasaku, K., et. al.
    • Journal Title

      Advanced Materials Research Vols.33-37

      Pages: 1037-1042

    • NAID

      110008459994

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 動脈瘤への流れとカテーテルの影響の解析-安全な血管内治療を目指して2009

    • Author(s)
      小西義史
    • Organizer
      第34回日本脳卒中学会
    • Place of Presentation
      松江
    • Year and Date
      2009-03-21
    • Related Report
      2008 Final Research Report
  • [Presentation] Endovascular Treatment of Intracranial Aneurysms : using new coils Clinical and experimental study2008

    • Author(s)
      Konishi Y
    • Organizer
      the 8th Meeting of the Asian-Australasian Federation of Interventional, Therapeutic
    • Place of Presentation
      Neuroradiology, Taiwan
    • Year and Date
      2008-04-18
    • Related Report
      2008 Final Research Report
  • [Presentation] 脳動脈瘤の分岐部血流評価2008

    • Author(s)
      小西善史, 塩川芳昭, 深作和明, 新井紀夫, 高倉葉子, 尾棹敦
    • Organizer
      第67回脳神経外科総会
    • Place of Presentation
      岩手
    • Related Report
      2008 Final Research Report
  • [Presentation] Numerical Study on Flow-Adaptive Stents2007

    • Author(s)
      Takakura, Y., Gulbahar W., Arai, N.,Konishi, Y., and Fukasaku, K.
    • Organizer
      FEOFS2007
    • Place of Presentation
      Urumqi, Xinjiang University, China
    • Year and Date
      2007-08-29
    • Related Report
      2008 Final Research Report
  • [Presentation] In vitro Study on Branch Flows with a Cerebral Aneurysm2007

    • Author(s)
      Osao, A., Gulbahar W., Takakura, Y.,Arai, N., Konishi, Y., Fukasaku, K., and Kikuchi, N.
    • Organizer
      FEOFS2007
    • Place of Presentation
      Urumqi, Xinjiang University, China
    • Year and Date
      2007-08-29
    • Related Report
      2008 Final Research Report
  • [Presentation] Numerical Simulation of Flows in a Pipe with an Aneurysmal Sac (Effects of Aneurysmal Models and Stents)2007

    • Author(s)
      Takakura, Y., Arai, N., Konishi, Y., and Fukasaku, K., et. al.
    • Organizer
      FEOFS 2007 (The 7th International Conference on Fracture and Strength of Solid, collaboration with International Conference on Computational Science and Engineering)
    • Place of Presentation
      Urumqi, Xinjian, China
    • Year and Date
      2007-08-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] Numerical Study on Flow-Adaptive Stents2007

    • Author(s)
      Takakura, Y., Arai, N., Konishi, Y., and Fukasaku, K., et. al.
    • Organizer
      FEOFS 2007 (The 7th International Conference on Fracture and Strength of Solid, collaboration with International Conference on Computational Science and Engineering)
    • Place of Presentation
      Urumqi, Xinjian, China
    • Year and Date
      2007-08-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] In vitro Study on Branch Flows with a Cerebral Aneurysm2007

    • Author(s)
      Takakura, Y., Arai, N., Konishi, Y., and Fukasaku, K., et. al.
    • Organizer
      FEOFS 2007 (The 7th International Conference on Fracture and Strength of Solid, collaboration with International Conference on Computational Science and Engineering)
    • Place of Presentation
      Urumqi, Xinjian, China
    • Year and Date
      2007-08-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] Numerical Simulation of Flows in a Pipe with an Aneurysmal Sac (Effects of Aneurysmal Models and Stents)2007

    • Author(s)
      Gulbahar W., Kobori, T., Takakura, Y., Arai, N., Konishi, Y., and Fukasaku, K.
    • Organizer
      FEOFS2007
    • Place of Presentation
      Urumqi, Xinjiang University, China
    • Year and Date
      2007-08-27
    • Related Report
      2008 Final Research Report
  • [Remarks]

    • URL

      http://www.tuat.ac.jp/~shok_lab/takakura/takakura.html

    • Related Report
      2007 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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