Promotion of branching activity of epithelial tissues
| Project/Area Number |
19570054
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Morphology/Structure
|
|---|
| Research Institution | Chiba University |
|---|
Principal Investigator |
NOGAWA Hiroyuki Chiba University, 大学院・理学研究科, 准教授 (40143250)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2007: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
|---|
| Keywords | マウス胚 / 唾液腺 / 肺 / 分枝形態形成 / 成長因子 / 上皮組織 / 遺伝子導入 / 分岐形態形成 / エレクトロポレーション |
|---|
| Research Abstract |
Branching is one of fundamental patterns of morphogenesis in developing organs of mammals. In the present study we revealed that the EGF family ligand-receptor system of embryonic mouse salivary glands becomes primed by the FGF ligand-receptor system to play an important role in the induction of branching morphogenesis. We also succeeded in introducing expression vectors into embryonic mouse lung epithelial tissues.
|
Report
(4 results)
Research Products
(5 results)
