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A Female-attracting activity of steroidal substances in the male abdominal gland of the newt

Research Project

Project/Area Number 19570061
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Morphology/Structure
Research InstitutionNara Medical University

Principal Investigator

FUMIYO Toyoda  Nara Medical University, 医学部, 講師 (10244708)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2007: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords動物形態 / イモリ / 腹腺 / 性フェロモン / ソデフリン / ステロイド
Research Abstract

雄イモリ腹部肛門腺のステロイド画分は雌誘引活性を有することを確認した。その成分である腹腺中プレグネノロンとアンドロステンダイオンの一部が腹腺の管腔内に生理的濃度で放出され、各々単独で雌イモリに対する誘引効果をもつことを示した。以前我々が明らかにした腹部肛門腺由来のペプチド性のフェロモン・ソデフリンの間には雌誘引活性に関して相乗効果が存在することから、両者は協調してフェロモンとして働くと考えられる。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (17 results)

All 2009 2008 2007

All Journal Article (10 results) (of which Peer Reviewed: 8 results) Presentation (7 results)

  • [Journal Article] Hormone-mediated reproductive behavior in the newt2009

    • Author(s)
      Kikuyama, S., Hasunuma, I., Toyoda, F., Haraguchi, S., Tsutsui, K.
    • Journal Title

      Ann. N. Y. Acad. Sci in press

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Female-attracting activity of steroids secreted by the abdominal gland of the male Cynops pyrrhogaster2009

    • Author(s)
      Toyoda,F.,Haraguchi, S., Matsunaga, M.,Tsutsui, K.,Nakada, T., et.al.
    • Journal Title

      J. Physiol. Sci 58(Suppl.)

    • NAID

      130007039216

    • Related Report
      2008 Final Research Report
  • [Journal Article] Hormone-mediated reproductive behavior in the newt.2009

    • Author(s)
      Kikuyama, S., Hasunuma, I., Toyoda, F., Haraguchi, S., Tsutsui, K.
    • Journal Title

      Ann. N. Y. Acad. Sci. (In press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Female-attracting activity of steroids secreted by the abdominal gland of the male Cynops pyrrhogaster.2008

    • Author(s)
      Toyoda, S., Haraguchi, S., Matsunaga, M., Tsutsui, K., Nakada, T., et al
    • Journal Title

      J. Physiol. Sci. 58(Suppl. )

    • NAID

      130007039216

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Isolation, characterization and bioactivity of region-specific pheromone, [Val^8]sodefrin from the newt2007

    • Author(s)
      Nakada,T., Toyoda, F., Iwata, T., Yamamoto, K., Conlon, JN., Kato, T. and Kikuyama, S.
    • Journal Title

      Cynops pyrrhogaster Peptides 28

      Pages: 774-780

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Molecular cloning of three types of arginine vasotocin receptor in the newt2007

    • Author(s)
      Hasunuma, I., Sakai, I., Nakada,T., Toyoda, F., Namiki, H. and Kikuyama, S
    • Journal Title

      Cynops pyrrhogaster. Gen. Comp. Endocrinol 151

      Pages: 252-258

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evidence for processing enzymes in the abdominal gland of the newt2007

    • Author(s)
      Nakada,T., Ishizuka, Y., Iwata, T., Toyoda, F., Kato, T. Conlon, JN and Kikuyama, S.
    • Journal Title

      Cynops pyrrhogaster. Zool. Sci 24

      Pages: 521-525

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Isolation,characterization and bioactivity of region-specific pheromone,[Val^8]sodefrin from the newt,Cynops pyrrhogaster.2007

    • Author(s)
      Nakada.T., Toyoda, F., Iwata.T., Yamamoto, K., Conlon, JN., Kato, T. and Kikuyama, S.
    • Journal Title

      Peptides 28

      Pages: 774-780

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular cloning of three types of arginine vasotocin receptor in the newt,Cynops pyrrhogaster.2007

    • Author(s)
      Hasunuma, I., Sakai, I., Nakada, T., Toyoda, F., Namiki, H. and Kikuyama, S.
    • Journal Title

      Gen.Comp.Endocrinol. 151

      Pages: 252-258

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evidence for processing enzymes in the abdominal gland of the newt,Cynops pyrrhogaster.2007

    • Author(s)
      Nakada, T., Ishizuka, Y., Iwata, T., Toyoda, F., Kato, T. Conlon, JN and Kikuyama, S.
    • Journal Title

      Zool.Sci. 24

      Pages: 521-525

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] イモリ求愛行動発現に関与するプロラクチンとアルギニンヴァソトシンの中枢作用2008

    • Author(s)
      豊田ふみよ, 蓮沼至, 山本和俊, 菊山榮
    • Organizer
      第33回日本比較内分泌学会大会
    • Place of Presentation
      広島大学
    • Year and Date
      2008-12-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] イモリ求愛行動発現に関するプロラクチン脳内作用機序2008

    • Author(s)
      豊田, 蓮沼, 原口, 山本, 筒井, 菊山
    • Organizer
      (社)日本動物学会第79回大会
    • Place of Presentation
      福岡大学
    • Year and Date
      2008-09-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] 菊山榮 イモリ求愛行動発現に関するプロラクチンとアルギニンヴァソトシンの中枢作用2008

    • Author(s)
      豊田ふみよ、蓮沼至、山本和俊
    • Organizer
      第33回日本比較内分泌学会大会
    • Place of Presentation
      広島
    • Related Report
      2008 Final Research Report
  • [Presentation] イモリ求愛行動発現に関するプロラクチン脳内作用機序2008

    • Author(s)
      豊田ふみよ、蓮沼至、原口省吾、山本和俊、筒井和義、菊山榮
    • Organizer
      第79回日本動物学会大会
    • Place of Presentation
      福岡
    • Related Report
      2008 Final Research Report
  • [Presentation] イモリのアルギニンバソトシンV3V1タイプ受容体の発現解析2007

    • Author(s)
      蓮沼至、山本和俊、豊田ふみよ、並木秀男、菊山榮
    • Organizer
      78回日本動物学会大会
    • Place of Presentation
      弘前
    • Related Report
      2008 Final Research Report
  • [Presentation] ニューロステロイド7α-ハイドロプレグネノロンは汚水森求愛行動発現に関与する2007

    • Author(s)
      豊田ふみよ、原口省吾、松永昌宏、中田友明、筒井和義、菊山榮
    • Organizer
      第78回日本動物学会大会
    • Place of Presentation
      弘前
    • Related Report
      2008 Final Research Report
  • [Presentation] イモリの側鼻腔に発現する鋤鼻受容体とGタンパク質2007

    • Author(s)
      中田友明、伊藤敦子、山岸公子、豊田ふみよ、長田俊哉、市川真澄、筒井和義、菊山榮
    • Organizer
      第78回日本動物学会大会
    • Place of Presentation
      弘前
    • Related Report
      2008 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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