Earwax gene analysis of the Yayoi skeletal remains of native and immigrant lineage.
| Project/Area Number |
19570227
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Anthropology
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| Research Institution | Nagasaki University |
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Principal Investigator |
SAIKI Kazunobiu Nagasaki University, 大学院・医歯藥業学総合研究院, 助教 (80195966)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHIURA Koichiro 長崎大学, 大学院・医歯藥学総合研究科, 教授 (00304931)
WAKEBE Tetsuaki 長崎大学, 大学院・医歯藥学総合研究科, 講師 (50124847)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 弥生人骨 / 耳垢型遺伝子 / 古代DNA |
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| Research Abstract |
The locus of the earwax gene was found by Yoshiura et al. in 2006. We tried the analysis of the earwax gene in Yayoi period human skeletal remains.【Materials】Fifty-one human skeletal remains excavated from the Yasunagata site in Tosu city, Saga prefecture, were analyzed very carefully. 【Methods】 We analyzed a SNP (rs17822931) of the ABCC11 by the Taq-Man PCR method got the high sensitivity results from a very small amount of nucleus DNA.【Result】 We were able to decide the earwax type of 5 skeletal remains ; the allele GA(the phenotype is Wet)were 3 samples, AA (the phenotype is Dry) were 2 samples.
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Report
(4 results)
Research Products
(24 results)
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[Journal Article] Earwax, osmidrosis, and breast cancer : why does one SNP(538G>A)in the human ABC transporter ABCC11 gene determine earwax type?2009
Author(s)
Toyoda Y, Sakurai A, Mitani Y, Nakashima M, Yoshiura KI, Nakagawa H, Sakai Y, Ota I, Lezhava A, Hayashizaki Y, Niikawa N, Ishikawa T
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Journal Title
FASEB Journal 23
Pages: 2001-2013
Related Report
Peer Reviewed
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