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Confirmation of standardized index of cerebral oxygenation incontinuous wave near-infrared spectroscopy based on physiological polymorphism

Research Project

Project/Area Number 19570232
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 生理人類学
Research InstitutionHokkaido University

Principal Investigator

NIIOKA Tadashi  Hokkaido University, 大学院・地球環境科学研究院, 准教授 (20123953)

Co-Investigator(Kenkyū-buntansha) TANAKA Gohichi  札幌医科大学, 医療人育成センター, 准教授 (10167497)
Research Collaborator OHNUKI Soichiro  北海道大学, 大学院・環境科学院修士課程, 大学院生
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords近赤外分光法 / 脳酸素動態 / 標準化指標 / 生理学 / 生理人類学 / 生理的多型 / 脳機能評価 / 生物・生体工学
Research Abstract

本研究で、認知課題遂行中の、脳内酸素化ヘモグロビン濃度、脱酸素化ヘモグロビン濃度、および総ヘモグロビン濃度について、絶対値計測が可能な時間分解近赤外分光法によって得られたデータを詳細に検討した結果、連続光方式近赤外分光法を用いた計測において、脳酸素動態数値計算モデルを構築すること、および標準化指標を見いだすことは極めて妥当であると考えられた。従って、数値計算モデル構築のための、安定的標準化指標としては、連続光方式近赤外分光法に基づいて我々が提唱する酸素化ヘモグロビン濃度と脱酸素化ヘモグロビン濃度の各変化分の比が有用であることが確立できたと考えられた。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (18 results)

All 2009 2008 2007

All Journal Article (9 results) (of which Peer Reviewed: 7 results) Presentation (9 results)

  • [Journal Article] Individual differencesin blood volume and oxygenation in thebrain during a cognitive task based ontime-resolved spectroscopic measurements2009

    • Author(s)
      Niioka, T., Ohnuki, S., Miyazaki, Y
    • Journal Title

      In Proceedings of International Society onOxygen Transport to Tissue 2008 (in press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Individual differences in blood volume and oxygenation in the brain during a cognitive task based on time-resolved spectroscopic measurements2009

    • Author(s)
      Niioka, T., Ohnuki, S., 他1名
    • Journal Title

      Proceedings of International Society on Oxygen Transport to Tissue 2008 (in press)(掲載決定)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 局所脳酸素動態の絶対値計測における改変Stroop色-語課題2連続遂行時の各ヘモグロビン濃度の変化および相互の関係について2009

    • Author(s)
      新岡正、大貫宗一郎, 他1名
    • Journal Title

      日本衛生学雑誌 64

      Pages: 560-560

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Individual differences in cerebralblood volume and oxygenation observedusing a time-resolved near-infraredspectroscopy system during executions of acognitive task.(T. Louts, M. Reitenbach,J. Molenbroek (Eds))2008

    • Author(s)
      Niioka, T., Ohnuki, S. , Miyazaki, Y
    • Journal Title

      Human Diversity : design for life, Proceedings of the 9thInternational Congress of PhysiologicalAnthropology. Faculty of Industrial DesignEngineering, Delft University ofTechnology, ICPA2008, Delft, theNetherlands

      Pages: 28-30

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Responses of ultra-weak chemiluminescenceand secretory IgA in saliva to theinduction of angry and depressive mood2008

    • Author(s)
      Tsuboi, H., Hamer, M., Tanaka, G.,Takagi, K., Kinae, N., Steptoe, A
    • Journal Title

      Brain, Behavior, and Immunity 22

      Pages: 209-214

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Responses of ultra-weak chemiluminescence and secretory IgA in saliva to the induction of angry and depressive mood2008

    • Author(s)
      Tsuboi, H., Hamer, M., Tanaka, G., 他3名
    • Journal Title

      Brain Behavior & Immunity 22

      Pages: 209-214

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 改変Stroop色-語課題の2連続遂行が脳酸素動態に及ぼす影響の個体差についての時間分解分光法による解析2008

    • Author(s)
      新岡 正, 大貫宗一郎, 宮崎良文
    • Journal Title

      日本衛生学雑誌 63

      Pages: 381-381

    • NAID

      10024477476

    • Related Report
      2007 Annual Research Report
  • [Journal Article] The effectsof depressive symptoms on cardiovascularand catecholamine responses to theinduction of depressive mood2007

    • Author(s)
      Hamer, M., Tanaka, G., Okamura, H.,Tsuda, A., Steptoe, A
    • Journal Title

      Biological Psychology 74

      Pages: 20-25

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effects of depressive symptoms on cardiovascular and catecholamine responses to the induction of depressive mood2007

    • Author(s)
      Hamer, M., Tanaka, G., 他3名
    • Journal Title

      Biological Psychology 74

      Pages: 20-25

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 局所脳酸素動態の絶対値計測における改変Stroop色-語課題2連続遂行時の各ヘモグロビン濃度の変化および相互の関係について.2009

    • Author(s)
      新岡正, 大貫宗一郎, 宮崎良文
    • Organizer
      第79回日本衛生学会
    • Place of Presentation
      東京
    • Year and Date
      2009-03-31
    • Related Report
      2008 Final Research Report
  • [Presentation] Individual differences in blood volume andoxygenation in the brain during executionsof a cognitive task2008

    • Author(s)
      Niioka, T., Ohnuki, S., Miyazaki, Y
    • Organizer
      9th InternationalCongress of Physiological Anthropology'Human Diversity : design for life'
    • Place of Presentation
      Delft, The Netherlands
    • Year and Date
      2008-08-23
    • Related Report
      2008 Final Research Report
  • [Presentation] Individual differences in blood volume and oxygenation in the brain during executions of a cognitive task2008

    • Author(s)
      Niioka, T., Ohnuki, S., 他1名
    • Organizer
      The 9^<th> International Congress of Physiological Anthropology
    • Place of Presentation
      Delft, Netherlands
    • Year and Date
      2008-08-23
    • Related Report
      2008 Annual Research Report
  • [Presentation] Finger arterial flowmediateddilation ratio modulated by serumestradiol and finger arterial elasticityin healthy young women2008

    • Author(s)
      Tanaka, G.
    • Organizer
      10th InternationalCongress of Behavioral Medicine
    • Place of Presentation
      Taisho University
    • Year and Date
      2008-08-02
    • Related Report
      2008 Final Research Report
  • [Presentation] 青年期女性の指動脈流量依存拡張率, 指動脈弾性特性と血清エストラジオール濃度の関係2008

    • Author(s)
      田中豪一
    • Organizer
      第26回日本生理心理学会大会
    • Place of Presentation
      那覇
    • Year and Date
      2008-07-06
    • Related Report
      2008 Final Research Report
  • [Presentation] 改変Stroop色-語課題遂行時の脳酸素動態の個体差2008

    • Author(s)
      新岡正, 大貫宗一郎,, 崎良文,
    • Organizer
      日本生理人類学会第58回大会
    • Place of Presentation
      大阪
    • Year and Date
      2008-06-07
    • Related Report
      2008 Final Research Report
  • [Presentation] 改変Stroop色-語課題の2連続遂行が脳酸素動態に及ぼす影響の個体差についての時間分解分光法による解析2008

    • Author(s)
      新岡正, 大貫宗一郎, 宮崎良文
    • Organizer
      第78回日本衛生学会
    • Place of Presentation
      熊本
    • Year and Date
      2008-03-31
    • Related Report
      2008 Final Research Report
  • [Presentation] Changes incerebral hemodynamics and cognitive-taskperformance after caffeine intake : individual differences and a high Inspiredoxygen concentration experiment2007

    • Author(s)
      Niioka, T, Yoshida, D.
    • Organizer
      JointMeeting of the Society for the Study ofHuman Biology and the Japan Society for theStudy of Physiological Anthropology 'Human Variation-from the laboratory to the field'
    • Place of Presentation
      Cambridge, UK
    • Year and Date
      2007-09-26
    • Related Report
      2008 Final Research Report
  • [Presentation] Changes in Cerebral Hemodynamics and Cognitive-Task Performance after Caffeine Intake: Individual Differences and a High Inspired Oxygen Concentration Experiment2007

    • Author(s)
      Niioka, T. and Yoshida, D.
    • Organizer
      Joint Meeting of the Society for the Study of Human Biology(SSHB)and the Japan Society for the Study of Physiological Anthropology
    • Place of Presentation
      Cambridge
    • Year and Date
      2007-09-26
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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