Studies on enzymes for organic sulfur compounds-cleavage and formation of carbon-sulfur bond
| Project/Area Number |
19580091
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Tottori University |
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Principal Investigator |
OHSHIRO Takashi Tottori University, 大学院・工学研究科, 教授 (00233106)
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| Co-Investigator(Kenkyū-buntansha) |
IZUMI Yoshikazu 鳥取大学, 大学院・工学研究科, 教授 (40026555)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2007: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 微生物脱硫 / ジベンゾチオフェン / オキシゲナーゼ / フコイダン / 硫酸化フカン / インドール / 難培養性微生物 / 脱硫酸化酵素 / Microbial desulfurization / Dibenzothiophene / indole / benzothiophene / Fucoidan / Desulfinase / Site-directed mutagenesis |
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| Research Abstract |
Enzymes acting on dibenzothiophene (DBT) and fucoidan were investigated ; DBT was contained in petroleum and fucoidan in algae. Since combustion of petroleum released substances for acid rain, "desulfurization" is a necessary step before combustion. DBT degrading enzymes was applicable to biodesulfurization, and the enzyme was improved by genetic engineering method in this study. Fucoidan is a high-molecular-weight compound with physiological activities such as anticancer one, and decreasing the molecular weight would lead to finding of new activities. Novel fucoidan-degrading microorganisms were isolated, and enzyme activities were detected in this study.
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Report
(4 results)
Research Products
(12 results)
