Salt-inducible chiral-nylon polymer from Bacillus megaterium : Synthesis and biochemical applications including an increase in halo-tolerance
| Project/Area Number |
19580092
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Applied microbiology
|
|---|
| Research Institution | Kochi University |
|---|
Principal Investigator |
ASHIUCHI Makoto Kochi University, 教育研究部自然科学系, 准教授 (20271091)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
永田 信治 高知大学, 農学部, 教授 (60180494)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
NAGATA Shinji 高知大学, 教育研究部自然科学系, 教授 (60180494)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | 微生物遺伝・育種 / 環境材料 / 生体材料 / 生体機能利用 / バイオテクノロジー / 環境適応 |
|---|
| Research Abstract |
We identified the industrial strain of Bacillus megaterium as a novel producer of L-type stereo-regular poly-γ-glutamate (PGA). Advanced analysis about PGA production of B. megaterium and cloning and sequencing of the genetic cluster responsible for the polymer synthesis and degradation, to examine stereo-regular PGA metabolism, were performed in the study. Additionally, in vivo and in vitro applicability of stereo-regular PGA as extremolyte-like materials was investigated as well.
|
Report
(4 results)
Research Products
(49 results)
