Requirement of PKC pathway of target yeast for toxicity of killer protein
| Project/Area Number |
19580100
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | National Institute for Agro-Environmental Sciences |
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Principal Investigator |
KITAMOTO Hiroko National Institute for Agro-Environmental Sciences, 生物生態機能研究領域, 主任研究員 (10370652)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 微生物機能 / 細胞内・細胞間情報伝達 / 膜輸送と輸送蛋白質 / 応用微生物 / シグナル伝達 / 抗生物質 / キチン合成酵素 / PKC経路 |
|---|
| Research Abstract |
Toxic subunit of Kluyveromyces lactis killer protein (zymocin), is transported into cell of sensitive yeast, Saccharomyces cerevisiae (SC). In this study we found that the activation of cell intregrity pathway (PKC pathway) of SC is needed for the transportation.
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Report
(4 results)
Research Products
(24 results)
