Food components activating thermosensitive TRP receptors and their effects to energy metabolism
| Project/Area Number |
19580146
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Food science
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| Research Institution | University of Shizuoka |
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Principal Investigator |
WATANABE Tatuo University of Shizuoka, 食品栄養科学部, 教授 (10210915)
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| Co-Investigator(Kenkyū-buntansha) |
MORITA Akihito 静岡県立大学, 食品栄養科学部, 助教 (40239653)
NARUKAWA Masataka 静岡県立大学, 食品栄養科学部, 助教 (50432349)
KOBATA Kenji 城西大学, 薬学部, 准教授 (70275105)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 食品成分 / TRPV1 / TRPA1 / エネルギー代謝 / 内蔵脂肪 / 生理活性 / TRP受容体 |
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| Research Abstract |
Food components activating TRPV1 were screened through 19 foods and found to be monoglycerides from hexane extracts of onion, myoga and wheat. Next, several TRPV1-activationg compounds were discovered from black pepper hexane extract. Monoglycerides and black pepper were effective to reduction of visceral fat deposition in mice. Further, new compounds activating TRPA1 were searched out from garlic, myoga and black pepper.
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Report
(4 results)
Research Products
(50 results)
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[Presentation] ミョウガ辛味関連物質Miogadial、Miogtrialとタデ辛味成分Polygodialは強力なTRPA1アゴニストである.2009
Author(s)
岩崎有作, 田辺学, 鹿山由子, 阿部雅子, 加塩麻紀子, 小泉佳奈子, 奥村由起子, 森光康次郎, 富永真琴, 小澤好夫, 渡辺達夫
Organizer
第24回日本香辛料研究会
Place of Presentation
大阪市
Related Report
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