Analysis of regulation on feline infectious peritonitis virus replication by RNA interference
| Project/Area Number |
19580351
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Basic veterinary science/Basic zootechnical science
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| Research Institution | Nippon Veterinary and Life Science University |
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Principal Investigator |
TANAKA Yoshikazu Nippon Veterinary and Life Science University, 獣医学部, 講師 (50291159)
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| Co-Investigator(Kenkyū-buntansha) |
盆子原 誠 日本獣医生命科学大学, 獣医学部, 講師 (50343611)
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| Co-Investigator(Renkei-kenkyūsha) |
BONKOBARA Makoto 日本獣医生命科学大学, 獣医学部, 講師 (50343611)
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| Project Period (FY) |
2007 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2007: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | ウイルス / 感染症 / ネコ / ncRNA / 遺伝子制御 / ノンコーディングRNA / ウイルス複製制御 |
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| Research Abstract |
fcwf-4細胞のFIPV感染実験においてウイルス複製に影響を与えるncRNAの分離・同定を試みた. マイクロDNA アレイによるmiRNA の解析を行い, hsa-miR-494 がウイルス感染時に2.1倍上昇することが明らかとなったが, hsa-miR-593, hsa-miR-193a-3p, hsa-miR-17 はそれぞれ0.11倍, 0.34倍, 0.44 倍と発現が減少した. 現在, 生理学的機能, 解析中である.
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Report
(3 results)
Research Products
(23 results)
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[Journal Article] Changes in metabolite, energy metabolism related enzyme activities and peripheral blood mononuclear cell (PBMC) populations in beef heifers with two differing liveweight change profiles in New Zealand2008
Author(s)
Mori A, Kenyon PR, Mori N, Yamamoto I, Tanaka Y, Suzuki N, Tazaki H, Ozawa T, Hayashi T, Hickson RE, Morris ST, Blair H, Arai T.
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Journal Title
Vet Res Commun(Epub 2007 Sep 12. PubMed PMID : 17849230) 32(2)
Pages: 159-66
Related Report
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[Journal Article] Plasma metabolite concentrations and hepatic enzyme activities in pregnant Romney ewes with restricted feeding2008
Author(s)
Tanaka Y, Mori A, Tazaki H, Imai S, Shiina J, Kusaba A, Ozawa T, Yoshida T, Kimura N, Hayashi T, Kenyon PR, Blair H, Arai T.
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Journal Title
Res Vet Sci(Epub 2007 Oct 24. PubMed PMID : 17920647) 85(1)
Pages: 17-21
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[Journal Article] Comparison of plasma metabolite concentrations and enzyme activities in beef cattle raised by different feeding systems in Korea, Japan and New Zealand2007
Author(s)
Mori A, Urabe S, Asada M, Tanaka Y, Tazaki H, Yamamoto I, Kimura N, Ozawa T, Morris ST, Hickson R, Kenyon PR, Blair H, Choi CB, Arai T.
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Journal Title
J Vet Med A Physiol Pathol Clin Med(PubMed PMID : 17718805) 54(7)
Pages: 342-5
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