Zoonotic importance of Strongyloides spp. taking wild animals as definitive hosts
| Project/Area Number |
19580355
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied veterinary science
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| Research Institution | Yamaguchi University |
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Principal Investigator |
SATO Hiroshi Yamaguchi University, 農学部, 准教授 (90211945)
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| Co-Investigator(Kenkyū-buntansha) |
HASEGAWA Hideo 大分大学, 医学部, 教授 (00126442)
YOKOYAMA Mayumi 兵庫県立大学, 自然環境科学研究所, 准教授 (50344388)
本道 栄一 山口大学, 農学部, 准教授 (30271745)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | Strongyloides / zoonosis / diagnosis / pathogenecity / 糞線虫 / 人獣共通寄生虫症 / 分子系統進化 / 病原性 / 人獣共通寄生虫 / 種鑑別 / 糞線虫症 / 人獣共通感染症 / 幼虫移行症 / 動物由来感染症 / 診断技術 / 分子系統分類学 |
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| Research Abstract |
Strongyloides spp. were obtained from a variety of wild animals, particularly primates in Japan and Africa. Genetic information such as 18S ribosomal RNA gene (rDNA) and the cox-1 region of mitochondrial DNA (COI) were collected. In this study, particular attention was paid to S. stercoralis and S. fuelleborni which are believed to infect both human beings and non-human primates. We found that four loop regions of the 18S rDNA of Strongyloides spp. are highly variable by species, and useful for species-differentiation. This technique together with genetic analyses of COI disclosed that S. fuelleborni kept by chimpanzees and a human patient working in the same region were identical, suggesting that human beings can be infected by S. fuelleborni maintained by wild non-human primates by chance. Simultaneously, distinct genetic backgrounds of morphologically identical S. fuelleborni distributed from Africa to Far East was indicated.
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Report
(4 results)
Research Products
(61 results)
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[Journal Article] Molecular identification of the causative agent of human strongyloidiasis acquired in Tanzania: dispersal and diversity of Strongyloides spp. and their hosts.2010
Author(s)
Hasegawa H, Sato H, Fujita S, Nguema P P M, Nobusue K, Miyagi K, Kooriyama T, Takenoshita Y, Noda S, Sato A, Morimoto A, Ikeda Y, Nishida T
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Journal Title
NAID
Related Report
Peer Reviewed
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[Journal Article] Molecular phylogeny of the subfamily Gerbillinae (Muridae, Rodentia) with emphasis on species living in the Xinjiang-Uygur Autonomous Region of China and based on the mitochondrial cytochrome b and cytochrome c oxicase subunit II genes.2010
Author(s)
Ito M, Jiang W, Sato J J, Zhen Q, Jiao W, Goto K, Sato H, Ishiwata K, Oku Y, Chai J-J, Kamiya H
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Journal Title
Zool Sci 27巻
Pages: 269-278
Related Report
Peer Reviewed
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[Journal Article] Detection of antibodies against Japanese encephalitis virus in raccoons, raccoon dogs and wild boars in Japan.2009
Author(s)
Ohno Y, Sato H, Suzuki K, Yokoyama M, Uni S, Shibasaki T, Sashika M, Inokuma H, Kai K, Maeda K
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Journal Title
J Vet Med Sci 71巻
Pages: 1035-1039
NAID
Related Report
Peer Reviewed
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