Molecular Structure Analysis on the Interactive Relations of Functionalized Compounds with NMR in Solution and Solid States
| Project/Area Number |
19590002
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Chiba University |
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Principal Investigator |
SEKI Hiroko Chiba University, 分析センター, 准教授 (60114245)
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| Co-Investigator(Kenkyū-buntansha) |
KUMAMOTO Takuya 千葉大学, 大学院・薬学研究院, 准教授 (50292678)
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| Project Period (FY) |
2007 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2007: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 機能性化合物 / 固体NMR / 分子間相互作用 / CP-MAS / 水素結合 / 分子間相亙作用 |
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| Research Abstract |
ビスグアニジン型化合物と各種酸性化合物との複合体を用い、単結晶X線解析や溶液・固体NMR を組み合わせた機能性化合物の分子間相互作用を含む構造解析を行った。ビスグアニジン-ヒ酸複合体の固体NMRは想定される本数よりも多いシグナルを示した。これは複合体中のグアニジン部位が非等価であるというX線解析の結果を反映したデータであり、固体NMRが分子間相互作用を持つ複合体の構造解析に有効な手段となる可能性を示した。
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Report
(3 results)
Research Products
(30 results)
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[Journal Article] Complexability of o-Bisguanidino- benzenes with Arsenic and Phosphoric Acids in Solution and Solid States,and the Potential Use of their Immobilized Derivatives as Solid Base Ligands for Metal Salts and Arsenic Acid2009
Author(s)
Ito, T., Suda, K., Kumamoto, T., Nakanishi, W., Watanabe, T. Ishikawa, T. Seki, H. Kawahata, M. Yamaguchi, K. Ogura, Y. Kazuo T. Suzuki
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Journal Title
Related Report
Peer Reviewed
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[Journal Article] NMR study on a novel mucin from jellyfish in natural abundance, qniumucin from Aurelia aurita2009
Author(s)
Uzawa, J., Urai, M., Baba, T., Seki, H., Taniguchi, K., Ushida, K
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Journal Title
J.Nat.Prod. 72巻
Pages: 818-823
Related Report
Peer Reviewed
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[Journal Article] Guanidine-Cata- lyzed Asymmetric Synthesis of 2,2-Disubstituted Chromane Skeletons by Intramolecular Oxa-Michael Addition2008
Author(s)
Saito, N., Ryoda, A., Nakanishi, W., Kumamoto, T., Ishikawa, T
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Journal Title
Eur.J.Org.Chem
Pages: 2759-2766
Related Report
Peer Reviewed
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