| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2007: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Research Abstract |
The oligosaccharide residues of glycoprotein and glycosphingolipids in mammalian tissues have been extensively studied for various biological recognition in recent years. In contrast, much less time has been devoted to structures of oligosaccharides from invertebrates that differ significantly from mammalian glycans. Due to these differences in the glycan structure we have been interested in the relationships between the structure and biological activity of oligosaccharides from invertebrate species, and in our continuing studies to elucidate the mechanism of host-parasite interaction. We carried out the synthesis of oligosaccharides from the helminth, Echinococcus multilocularis, Ascaris suum, Schistosoma mansoni and Zygomycetes species Mucor hiemalis, and got target oligosaccharides more than twenty kinds.
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