Studies on the various biological functions of the constituents from edible fruits
| Project/Area Number |
19590030
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Tokai University (2008-2009)
Kyushu Tokai University (2007) |
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Principal Investigator |
ONO Masateru Tokai University, 農学部, 教授 (60177269)
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| Co-Investigator(Kenkyū-buntansha) |
MASUOKA Chikako 東海大学, 阿蘇教学課, 上級技術員 (50446134)
YASUDA Shin 東海大学, 農学部, 講師 (10512923)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2009: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2008: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2007: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
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| Keywords | 食用果実 / 機能性成分 / 化学構造 / 生物活性 / 抗酸化活性 / トマト / セイヨウニンジンボク / 癌細胞増殖抑制活性 / キサンチンオキダーゼ阻害活性 / ヒアルロニダーゼ阻害活性 / 構造解析 / クロマメノキ / ピンクペッパー / ナス |
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| Research Abstract |
For the elucidation of the various biological functions of the edible fruits, we studied on the constituents from the fruits of Lycopersicon esculentum, Vaccinium uliginosum L., Solanum melongena L., Schinus molle L., and Vitex agnus-castus L.These studies resulted in the isolation and structural elucidation of 98 compounds including 20 new compounds. In addition, antioxidative activities, antiproliferative activity against cancer cells, antigout activity, and antiinflammation activity of the extracts and some constituents from the fruits were examined and some extracts and constituents showed the activities.
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Report
(4 results)
Research Products
(26 results)
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[Journal Article] Five New Diterpenoids, Viteagnusins A-E, from the Fruit of Vitex agnus-castus2008
Author(s)
M. Ono, T. Yamasaki, M. Konoshita,, T. Ikeda, M. Okawa, J. Kinjo, H. Yoshimitsu, T. Nohara
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Journal Title
Chem. Pharm. Bul 56
Pages: 1621-1624
NAID
Related Report
Peer Reviewed
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[Presentation] トマト成熟果実の成分について(3)2009
Author(s)
塩野有希, 古澤知里, 稲葉慎也, 田中孝幸, 安田伸, 小野政輝, 藤原章雄, 池田剛, 塚本佐知子, 野原稔弘
Organizer
日本生薬学会第56回年会
Place of Presentation
京都市
Year and Date
2009-10-04
Related Report
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[Presentation] トマト成熟果実の成分について(3)2009
Author(s)
塩野有希, 古澤知里, 稲葉慎也, 田中孝幸, 安田伸, 小野政輝, 藤原章雄, 池田剛, 塚本佐知子, 野原稔弘
Organizer
日本生薬学会第56回年会
Place of Presentation
京都薬科大学
Year and Date
2009-10-04
Related Report
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[Presentation] タイ産ナス果実の成分について2007
Author(s)
田中なみ, 橋本脩平, 増岡智加子, 井越敬司, 飯田善彦, 池田剛, 野原稔弘, 小野政輝
Organizer
平成19年度日本栄養・食糧学会九州・沖縄支部大会
Place of Presentation
熊本市
Year and Date
2007-09-29
Related Report
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