Investigation of fibrinolytic system on differentiation of adipocytes and establishment of therapeutic strategy
Project/Area Number |
19590090
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Biological pharmacy
|
Research Institution | Doshisha Women's College of Liberal Arts |
Principal Investigator |
MATSUNO Hiroyuki Doshisha Women's College of Liberal Arts, 薬学部, 教授 (40273148)
|
Co-Investigator(Kenkyū-buntansha) |
WADA Kahon 同志社女子大学, 薬学部, 准教授 (00314427)
黒木 綾 同志社女子大学, 薬学部, 助手 (50411088)
|
Project Period (FY) |
2007 – 2008
|
Project Status |
Completed (Fiscal Year 2008)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2007: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
Keywords | plasmin / uPAR / adipocyte / migration / proliferation / antiplasmin / TGF-beta / fibrosis / ATPase / alpha2-antiplasmin |
Research Abstract |
21世紀を迎え、我国の食生活や環境は欧米化というよりむしろ新たな独自性をもった日本スタイルを生み出していると考えられる。このような状況下で、本研究は脂肪細胞の分化・誘導に関して新しい観点から線溶系因子の関与ならびに発生学的に重要なプロトンポンプの意義について探求した。
|
Report
(3 results)
Research Products
(18 results)