• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Molecular and morphological analysis on the physiological significance of sex steroid synthesis in the thyroid gland

Research Project

Project/Area Number 19590177
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General anatomy (including Histology/Embryology)
Research InstitutionWakayama Medical University

Principal Investigator

TSURUO Yoshihiro  Wakayama Medical University, 医学部, 教授 (90207449)

Co-Investigator(Kenkyū-buntansha) UEYAMA Takashi  和歌山県立医科大学, 医学部, 准教授 (50264875)
ITO Takao  和歌山県立医科大学, 医学部, 助教 (30315931)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2007: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywordsステロイド代謝酵素 / 性ステロイド / 甲状腺 / 濾胞上皮細胞 / 傍濾胞細胞 / 形態学
Research Abstract

甲状腺ホルモン(サイロキシン : T4、トリヨードサイロニン : T3)とカルシトニンの甲状腺での合成と分泌は、他のステロイド標的器官と同様に、生殖腺から分泌され血行性に到達する性ステロイドによって調節されるものと信じられていた。しかし我々は今回の研究で甲状腺内に性ステロイド代謝酵素が発現することを確認し、甲状腺ホルモンが甲状腺内で合成される性ステロイドによって機能調節される可能性を見出した。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (19 results)

All 2008 2007

All Journal Article (8 results) (of which Peer Reviewed: 5 results) Presentation (11 results)

  • [Journal Article] Adaptive HNE-Nrf2-HO1 pathway against oxidative stress is associated with acute gastric mucosal lesions2008

    • Author(s)
      Ueda K, Ueyama T, Yoshida K, Kimura H, Ito T, Shimizu Y, Oka M, Tsuruo Y, Ichinose M
    • Journal Title

      Am J Physiol 295

    • Related Report
      2008 Final Research Report
  • [Journal Article] Catecholamines and estrogen are involved in the pathogenesis of emotional stress-induced acute heart attack2008

    • Author(s)
      Ueyama T, Kasamatsu K, Hano T, Tsuruo Y, Ishikura F
    • Journal Title

      Ann NY Acad Sci 1148

      Pages: 479-480

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] エストロゲンは心血管系と神経系とに作用し、情動的ストレスとカテコラミンで誘発される急性心不全を改善する2008

    • Author(s)
      上山敬司, 鶴尾吉宏, 石蔵文信
    • Journal Title

      自律神経 45

      Pages: 98-100

    • NAID

      10024485896

    • Related Report
      2008 Final Research Report
  • [Journal Article] Adaptive HNE-Nrf2-H01 pathway against oxidative stress is as sociated with acute gastric mucosal lesions.2008

    • Author(s)
      Ueda K, et al.
    • Journal Title

      Am J Physiol 295

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Catecholamines and estrogen are involved in the pathogenesis of emotional stress-induced acute heart attack.2008

    • Author(s)
      Ueyama T, et al.
    • Journal Title

      Ann NY Acad Sci 1148

      Pages: 479-480

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] エストロゲンは心血管系と神経系とに作用し、情動的ストレスとカテコラミンで誘発される急性心不全を改善する.2008

    • Author(s)
      上山敬司ら
    • Journal Title

      自律神経 45

      Pages: 98-100

    • NAID

      10024485896

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Chronic estrogen supplementation following ovariectomy improves the emotional stress-induced cardiovascular responses by indirect action on the nervous system and by direct action on the heart2007

    • Author(s)
      Ueyama T, Ishikura F, Matsuda A, Asanuma T, Ueda K, Ichinose M, Kasamatsu K, Hano T, Akasaka T, Tsuruo Y, Morimoto K, Beppu S
    • Journal Title

      Circ J 71

      Pages: 565-573

    • NAID

      110006272149

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Chronic estrogen supplementation following ovariectomy improves the emotional stress-induced cardiovascular responses by indirect action on the nervous system and by direct action on the heart2007

    • Author(s)
      Ueyama T, et. al.
    • Journal Title

      Circ J 71

      Pages: 565-573

    • NAID

      110006272149

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] たこつぼ心筋症モデルにおける、ヘムオキシゲナーゼの増加2008

    • Author(s)
      上山敬司, 鶴尾吉宏
    • Organizer
      第61回日本自律神経学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-11-07
    • Related Report
      2008 Final Research Report
  • [Presentation] たこつぼ心筋症モデルにおける、ヘムオキシゲナーゼの増加.2008

    • Author(s)
      上山敬司ら
    • Organizer
      第61回日本自律神経学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-11-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] PolaprezincによるHO-1誘導作用2008

    • Author(s)
      上田和樹, 上山敬司, 岡政志, 鶴尾吉宏,一瀬雅夫
    • Organizer
      第50回日本消化器病学会
    • Place of Presentation
      東京
    • Year and Date
      2008-10-01
    • Related Report
      2008 Final Research Report
  • [Presentation] PolaprezincによるHO-1誘導作用.2008

    • Author(s)
      上田和樹ら
    • Organizer
      第50回日本消化器病学会
    • Place of Presentation
      東京
    • Year and Date
      2008-10-01
    • Related Report
      2008 Annual Research Report
  • [Presentation] 情動的ストレス誘発心不全におけるヘムオキシゲナーゼの増加2008

    • Author(s)
      上山敬司, 伊藤隆雄, 鶴尾吉宏
    • Organizer
      第113回日本解学会総会
    • Place of Presentation
      大分
    • Year and Date
      2008-03-29
    • Related Report
      2008 Final Research Report
  • [Presentation] Surge of catecholamines and reduction of estrogen trigger the emotional stress-induced acute cardiac dysfunction in human and in rat2007

    • Author(s)
      Ueyama T, Tsuruo Y, Akashi YJ
    • Organizer
      Satellite symposium of 5th congress of the international society for autonomic neuroscience
    • Place of Presentation
      Wakayama, Japan
    • Year and Date
      2007-10-03
    • Related Report
      2008 Final Research Report
  • [Presentation] Surge of catecholamines and reduction of estrogen trigger the emotional stress-induced acute cardiac dysfunction in human and in rat.2007

    • Author(s)
      Ueyama T, et. al.
    • Organizer
      Satellite symposium of 5th congress of the international society for autonomic neuroscience
    • Place of Presentation
      Wakayama,Japan
    • Year and Date
      2007-10-03
    • Related Report
      2007 Annual Research Report
  • [Presentation] Estrogen modulates the emotional stress- and catecholamine-induced acute heart failure2007

    • Author(s)
      4. Ueyama T, Tsuruo Y
    • Organizer
      5th congress of the international society for autonomic neuroscience
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] Catecholamine and estrogen are involved in the pathogenesis of stress-induced acute heart attack2007

    • Author(s)
      Ueyama T, Tsuruo Y, Ishikura F
    • Organizer
      9th symposium on catecholamines and other neurotransmitters in stress
    • Place of Presentation
      Smolenice Castle,S lovakia
    • Related Report
      2008 Final Research Report
  • [Presentation] Catecholamine and estrogen are involved in the pathogenesis of stress-induced acute heart attack.2007

    • Author(s)
      Ueyama T, et. al.
    • Organizer
      9th symposium on catecholamines and other neurotransmitters in stress
    • Place of Presentation
      Smolenice Castle,Slovakia
    • Related Report
      2007 Annual Research Report
  • [Presentation] Estrogen modulates the emotional stress-and catecholamine-induced acute heart failure.2007

    • Author(s)
      Ueyama T, Tsuruo Y
    • Organizer
      5th congress of the international society for autonomic neuroscience
    • Place of Presentation
      Kyoto,Japan
    • Related Report
      2007 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi