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The association and origin of tissue factor in deep venous thrombosis

Research Project

Project/Area Number 19590356
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Human pathology
Research InstitutionUniversity of Miyazaki

Principal Investigator

佐藤 勇一郎  University of Miyazaki, 医学部, 助教 (90347055)

Co-Investigator(Kenkyū-buntansha) 丸塚 浩助  宮崎大学, 医学部, 准教授 (00239154)
畠山 金太  宮崎大学, 医学部, 講師 (60325735)
山下 篤  宮崎大学, 医学部, 助教 (90372797)
浅田 祐士郎  宮崎大学, 医学部, 教授 (70202588)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2007: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords循環器 / 静脈血栓症 / 組織因子 / 病理 / 深部静脈血栓症 / 肺血栓症 / 免疫染色 / 動物モデル
Research Abstract

ヒト静脈血栓症において組織因子の明らかな発現増加は認められず、動物実験においてもそその発現増加はなかった。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (12 results)

All 2009 2008 2007 Other

All Journal Article (7 results) (of which Peer Reviewed: 5 results) Presentation (4 results) Remarks (1 results)

  • [Journal Article] Incidence of asymptomatic coronary thrombosis and plaque disruption : Comparison of non-cardiac and cardiac deathsamong autopsy cases2009

    • Author(s)
      Sato Y, Hatakeyama K, Marutsuka K, Asada Y.
    • Journal Title

      Thromb Res 124

      Pages: 19-23

    • Related Report
      2008 Final Research Report
  • [Journal Article] Thioredoxin in coronary culprit lesions : Possible relationship to oxidative stress and intraplaque hemorrhage2008

    • Author(s)
      Nishihira K, Yamashita A, Imamura T, Hatakeyama K, Sato Y, Nakamura H, Yodoi J, Ogawa H, Kitamura K, Asada Y.
    • Journal Title

      Atherosclerosis 201

      Pages: 360-367

    • Related Report
      2008 Final Research Report
  • [Journal Article] Thioredoxin in coronary culprit lesions : Possible relationship to oxidative stress and intraplaque hemorrhage.2008

    • Author(s)
      Nishihira K, Sato Y
    • Journal Title

      Atherosclerosis 201

      Pages: 360-367

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hypereosinophilic syndrome associated with occlusive coronary thrombosis and right ventricular thrombus.2008

    • Author(s)
      Sato Y
    • Journal Title

      Pathology International 58

      Pages: 138-141

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tissue factor pathway inhibitor is highly susceptible to chymase-mediated proteolysis2007

    • Author(s)
      Hamuro
    • Journal Title

      FEBESJ 274

      Pages: 3065-3077

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of interleukin-18 in coronary plaque obtained by atherectomy from patients with stable and unstable angina.2007

    • Author(s)
      Nishihira
    • Journal Title

      Thromb Res 121

      Pages: 275-277

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome2007

    • Author(s)
      Miyoshi
    • Journal Title

      Circulation 116

      Pages: 1226-1233

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 血液凝固因子XIは深部静脈血栓症に存在しトロンビン産生を介して血栓の成長に関与する2008

    • Author(s)
      高橋良咲、山下篤、佐藤勇一郎、浅田祐士郎
    • Organizer
      第31回日本血栓止血学会学術集会
    • Place of Presentation
      大阪府大阪市
    • Related Report
      2008 Final Research Report
  • [Presentation] 脳腫瘍血管の病理組織学的検討2008

    • Author(s)
      佐藤信也、佐藤勇一郎、丸塚浩助、浅田祐士郎
    • Organizer
      第97回日本病理学会総会
    • Place of Presentation
      石川
    • Related Report
      2008 Final Research Report
  • [Presentation] 血液凝固因子XIは深部静脈血栓症に存在しトロンビン産生を介して血栓の成長に関与する2008

    • Author(s)
      高橋良咲, 佐藤勇一郎
    • Organizer
      第31回日本血栓止血学会学術集会
    • Place of Presentation
      大阪市
    • Related Report
      2008 Annual Research Report
  • [Presentation] 非心臓死剖検例における冠動脈血栓の病理組織学的検討2007

    • Author(s)
      佐藤 勇一郎
    • Organizer
      第39回日本動脈硬化学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-13
    • Related Report
      2007 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.miyazaki-u.ac.jp/pathol

    • Related Report
      2007 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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