Pathophysiological analysis of the emesis induced by Staphyrococcal enterotoxin
| Project/Area Number |
19590444
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Bacteriology (including Mycology)
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| Research Institution | Osaka University |
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Principal Investigator |
SUGIMOTO Nakaba Osaka University, 大学院・医学系研究科, 教授 (20142317)
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| Project Period (FY) |
2007 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 感染免疫 / 食中毒 / ブドウ球菌 / エンテロトキシン / 消化管蠕動運動 / パターンジェネレーター / 嘔吐運動 |
|---|
| Research Abstract |
Mouse small intestine twitch in response to electrical field stimulation. The response were composed of two peaks, a fast peak which appears after ca. 1 sec and the second sloe peak which appears after ca. 2.5 sec. The amplitude of the second peak increased remarkably after the treatment of the intestinal preparation with staphyrococcal eneterotoxin A. Monoamine seemed to mediate the second peak but CPG activity in CNS of the crayfish which is reported to be mediated by monoamines showed no obvious change by the enterotoxin.
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Report
(6 results)
Research Products
(28 results)
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[Journal Article] Comparison of effects of botulinum toxin subtyoe A1 and A2 using twitch tension assay and rat grip strength test.2011
Author(s)
Torii, Y., N. Kiyota, N. Sugimoto, Y. Mori, Y. Goto, T. Harakawa, S. Nakahira, R. Kaji, S. Kozaki, A. Ginnaga
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Journal Title
Related Report
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[Journal Article] Characterization of the human herpesuvirus 6 U69 gene product and identification of its nuclear localization signal.2008
Author(s)
Yuji Isegawa, Yoichi Miyamoto, Yoshinari Yasuda, Katsunori Semi, Kenji Tsujimura, Rikiro Fukunaga, Atsushi Ohshima, Yasuhiro Horiguchi, Yoshihiro Yoneda, Nakaba Sugimoto
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Journal Title
Journal of Virology 82, No.2
Pages: 710-718
Related Report
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[Journal Article] Characterization of the human herpesuvirus 6 U69 gene product and identification of its nuclear localization signal2008
Author(s)
Yuji Isegawa, Yoichi Miyamoto, Yoshinari Yasuda, Katsunori Semi, Kenji Tsujimura, Rikiro Fukunaga, Atsushi Ohshima, Yasuhiro Horiguchi, Yoshihiro Yoneda, Nakaba Sugimoto
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Journal Title
Journal of Virology 82, No. 2
Pages: 710-718
Related Report
Peer Reviewed
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