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Development of health evaluation support system based on the self-organizing map technique

Research Project

Project/Area Number 19590562
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Laboratory medicine
Research InstitutionYamaguchi University

Principal Investigator

ICHIHARA Kiyoshi  Yamaguchi University, 大学院・医学研究科, 教授 (10144495)

Co-Investigator(Kenkyū-buntansha) 片岡 浩巳  高知大学, 医学部附属病院, 臨床検査技師 (80398049)
Co-Investigator(Renkei-kenkyūsha) KATAOKA Hiromi  高知大学, 医学部附属病院, 助教 (80398049)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2007: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywordsデータマイニング法 / 自己組織化マップ / 自己組織化病態系統樹法 / 予防医学 / 発症前診断 / メタボリックシンドローム / 健診業務支援システム
Research Abstract

大規模な健診結果に自己組織化マップ(SOM)法を適用し、種々の健常、発症前、疾患のパターンを識別するシステムの開発を行った。システムの評価には、某健診センターの8年間47,160件、26検査項目と基本身体計測値と生活習慣質問票よりなる健診結果情報(14,358名1人平均3.5回)を用いた。その結果、SOM法により健常人に現れやすい多様な病型とその発症前病型を分別できたが、その構成は男女で大きく異なった(男性では代謝症候群に属する病型が多いが、女性では少ない、等)。本研究では、得られた病型間の類似度から、その相互関連を病態系統樹の形に自動展開する機能を実装した。さらに(1) 各病型群と健常典型群の生活習慣上の差異を多重ロジスティック分析で即座に解析・提示する機能、(2) 受診者の病型の経年変化を個別に図示する機能を追加した。これらの改善により、効果的な健診後指導を可能とした。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (5 results)

All 2008

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (4 results)

  • [Journal Article] Clustering of health-check test results into a novel self-organizing tree of diagnostic categories.2008

    • Author(s)
      K. Ichihara, et al.
    • Journal Title

      Clin Chem 54(S6)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Clustering of health-check test results into a novel self-organizing tree of diagnostic categories2008

    • Author(s)
      Ichihara K, Kataoka H, Nakajima N, Urano S
    • Organizer
      Clin Chem
    • Place of Presentation
      2008 Anual Meeting forAm Assoc Clin Chem, Washington DC(54(S6) : 59)
    • Year and Date
      2008-07-29
    • Related Report
      2008 Final Research Report
  • [Presentation] Clustering of health-check test results into a novel self-organizing tree of diagnostic categories.2008

    • Author(s)
      Kiyoshi Ichihara
    • Organizer
      2008 Annual Meeting of American Association of Clinical Chemistry
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2008-07-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] Practical application of data-mining methods in laboratory medicine2008

    • Author(s)
      Ichihara K.
    • Organizer
      The 6th International Conference of Clinical Laboratory Automation and Robotics
    • Place of Presentation
      Kobe
    • Year and Date
      2008-04-19
    • Related Report
      2008 Final Research Report
  • [Presentation] Practical application of data-mining Methods in laboratory medicine.2008

    • Author(s)
      Kiyoshi Ichihara
    • Organizer
      The 6^<th> International Conference of Clinical Laboratory Automation and Robotics.
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2008-04-19
    • Related Report
      2008 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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