The diagnosis of acute myeloid leukemia based on the new WHO classification in the multicenter study.
| Project/Area Number |
19590565
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
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| Research Institution | University of the Ryukyus |
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Principal Investigator |
KURIYAMA Kazutaka University of the Ryukyus, 医学部, 教授 (90128174)
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| Co-Investigator(Kenkyū-buntansha) |
宮崎 泰司 長崎大学, 医学部・歯学部附属病院, 講師 (40304943)
波多 智子 長崎大学, 医学部・歯学部付属病院, 助教 (10346968)
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| Co-Investigator(Renkei-kenkyūsha) |
MIYAZAKI Yasushi 長崎大学, 医学部・歯学部附属病院, 講師 (40304943)
HATA Tomoko 長崎大学, 医学部・歯学部附属病院, 助教 (10346968)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 急性骨髄性白血病 / WHO分類 / 中央診断システム / 染色体異常 / 遺伝子異常 / 予後因子 / FAB分類 / 子後因子 |
|---|
| Research Abstract |
We diagnosed the patients registered with AML treatment protocol (AML-97) of Japan Adult Leukemia Study Group according to WHO classification in 2001.628 patients registered with the AML-97 protocol were diagnosed as AML with recurrent genetic abonrmalities (171patients;26.8%), AML with multilineage dysplasia (133;20.8%), AML not otherwise categorized (331;51.9%) or acute leukemia of ambiguous lineage (3;0.5%), respectively. These diagnoses were not so different from the diagnoses by the revised WHO classification in 2008, except that 32 patients having 11q23 abnormalities decreased to 9 patients because only t(9;11) was taken up in 2008.
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Report
(4 results)
Research Products
(66 results)
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[Journal Article]2009
Author(s)
栗山一孝
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Journal Title
改訂第4版造血器腫瘍アトラス形態、免疫、染色体と遺伝子(日本医事新報社)
Pages: 263-267
Related Report
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[Journal Article]2009
Author(s)
栗山一孝
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Journal Title
WHO分類第4版による白血病・リンパ系腫瘍の病態学(中外医学社)
Pages: 71-86
Related Report
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[Journal Article]2009
Author(s)
宮崎泰司
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Journal Title
血液疾患診療ハンドブック -診療の手引きと臨床データ集- 改訂版(医薬ジャーナル社)
Pages: 130-156
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