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Associations of Psychological Factors with Inflammation, Metabolic Disorder, and Autonomic Function

Research Project

Project/Area Number 19590629
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionOsaka University

Principal Investigator

OHIRA Tetsuya  Osaka University, 医学系研究科, 准教授 (50448031)

Co-Investigator(Kenkyū-buntansha) ISO Hiroyasu  大阪大学, 医学系研究科, 教授 (50223053)
TANIGAWA Takeshi  愛媛大学, 医学系研究科, 教授 (80227214)
IMANO Hironori  大阪大学, 医学系研究科, 助教 (90450923)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2007: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords成人保健 / ストレス / うつ / 炎症 / 代謝異常 / 自律神経 / 自覚的ストレス / うつ症状 / 楽観的思考 / 社会的支援 / 生活習慣 / メタボリックシンドローム / 糖尿病 / 疫学研究
Research Abstract

We sought o examine associations of psychological factors with life style, inflammation, metabolic syndrome, and autonomic function among Japanese men and women. In a 3-year prospective analysis, perceive stress, physical activity, over working time, and insufficient sleep were associated with the risk of depressive symptoms. In a cross-sectional analysis, stressful life event, anger, chronic fatigue, and hopelessness were associated with high sensitive C reactive protein levels, prevalence of metabolic syndrome, and increased sympathetic functions.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (33 results)

All 2010 2009 2008 2007

All Journal Article (20 results) (of which Peer Reviewed: 16 results) Presentation (13 results)

  • [Journal Article] Associations of psychological distress with cardiovascular disease and its risk factors: the Circulatory Risk in Communities Study(CIRCS)2010

    • Author(s)
      Ohira T.
    • Journal Title

      Journal of Epidemiology 20

      Pages: 185-191

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Associations of psychological distress with cardiovascular disease and its risk factors : the Circulatory Risk in Communities Study (CIRCS)2010

    • Author(s)
      大平哲也
    • Journal Title

      Journal of Epidemiology (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Perceived level of life enjoyment and risks of cardiovascular disease incidence and mortality: The JPHC Study. Circuletion2009

    • Author(s)
      Shirai K, Iso H, Ohira T, Ikeda A, Noda H, Honjo K, Inoue M, Tsugane S
    • Journal Title

      Japan Public Health Center-Based Study Group 120

      Pages: 956-963

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of habitual alcohol intake on ambulatory blood pressure, heart rate, and its variability among Japanese men2009

    • Author(s)
      Ohira T, Tanigawa T, Tabata M, Imano H, Kitamura A, Kiyama M, Sato S, Okamura T, Cui R, Koike KA, Shimamoto T, Iso H.
    • Journal Title

      Hypertension 53

      Pages: 13-19

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Perceived level of life enjoyment and risks of cardiovascular disease incidence and mortality : The JPHC Study2009

    • Author(s)
      白井こころ, 大平哲也, 他
    • Journal Title

      Circulation 120

      Pages: 956-963

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of habitual alcohol intake on ambulatory blood pressure, heart rate, and its variability among Japanese men.2009

    • Author(s)
      Tetsuya Ohira, et al.
    • Journal Title

      Hypertension 53

      Pages: 13-19

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The joint impact of self-reported behaviors of eating quickly and eating until full on overweight: results of a cross sectional survey2008

    • Author(s)
      aruyama K, Sato S, Ohira T, Maeda K, Noda H, Kubota Y, Nishimura S, Kitamura A, Kiyama M, Okada T, Imano H, Nakamura M, Ishikawa Y, Kurokawa M, Sasaki S, Iso H. The joint impact of self-report
    • Journal Title

      BMJ 337

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] メタボリックシンドロームの心血管リスク虚血性心疾患vs脳卒中2008

    • Author(s)
      大平哲也, 磯博康
    • Journal Title

      ebmジャーナル 9

      Pages: 14-18

    • Related Report
      2009 Final Research Report
  • [Journal Article] 本邦脂質異常症の現況と脳卒中発症-疫学的検討の変遷-2008

    • Author(s)
      大平哲也, 磯博康
    • Journal Title

      生活習慣病と成人病 38

      Pages: 134-138

    • Related Report
      2009 Final Research Report
  • [Journal Article] メタボリックシンドローム構成因子に及ぼす肥満と生活習慣の影響についての縦断研究2008

    • Author(s)
      木山昌彦, 大平哲也, 北村明彦, 今野弘規, 岡田武夫, 佐藤眞一, 前田健次, 中村正和, 石川善紀, 嶋本喬, 野田博之, 磯博康
    • Journal Title

      厚生の指標 55

      Pages: 1-5

    • NAID

      40016374647

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Associations of psychosocial factors with heart rate and its short-term variability: multi-ethnic study of atherosclerosis2008

    • Author(s)
      Ohira T, Diez Roux AV, Prineas RJ, Kizilbash MA, Carnethon MR, Folsom AR
    • Journal Title

      Psychosomatic Medicine 70

      Pages: 141-146

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Longitudinal association of serum carotenoids and tocopherols with hostility: the CARDIA study2008

    • Author(s)
      Ohira T, Hozawa A, Iribarren C, Daviglus ML, Matthews KA, Gross MD, Jacobs DR Jr
    • Journal Title

      American Journal of Epidemiology 167

      Pages: 42-50

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] メタボリックシンドロームの心血管リスク 虚血性心疾患VS脳卒中.2008

    • Author(s)
      大平哲也, 他
    • Journal Title

      EBMジャーナル 9

      Pages: 14-18

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 本邦脂質異常症の現況と脳卒中発症-疫学的検討の変遷-2008

    • Author(s)
      大平哲也, 他
    • Journal Title

      生活習慣病と成人病 38

      Pages: 134-138

    • Related Report
      2008 Annual Research Report
  • [Journal Article] メタボリックシンドローム構成因子に及ぼす肥満と生活習慣の影響についての縦断研究2008

    • Author(s)
      木山昌彦, 大平哲也, 他
    • Journal Title

      厚生の指標 55

      Pages: 1-5

    • NAID

      40016374647

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The joint impact of self-reported behaviors of eating quickly and eating until full on overweight : results of a cross sectional survey2008

    • Author(s)
      Maruyama K, Ohira T, et al.
    • Journal Title

      BMJ 337

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Associations of psychosocial factors with heart rate and its short-term variability: the Multi-Ethnic Study of Atherosclerosis.2008

    • Author(s)
      Tetsuya Ohira, et. al.
    • Journal Title

      Psychosomatic Medicine 70

      Pages: 141-146

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Longitudinal association of serum carotenoids and tocopherols with hostility.2008

    • Author(s)
      Tetsuya Ohira, et. al.
    • Journal Title

      American Journal of Epidemiology 167

      Pages: 42-50

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 心理的健康の維持・増進のための望ましい生活習慣についての疫学研究2007

    • Author(s)
      大平哲也, 中村知佳子, 今野弘規, 岡田武夫, 北村明彦, 木山昌彦, 中川裕子, 佐藤眞一, 中村正和, 内藤義彦, 黒川通典, 仲下祐美子, 山本雅代, 亀井和代, 堀井裕子, 嶋本喬
    • Journal Title

      日本公衆衛生雑誌 54

      Pages: 226-235

    • NAID

      10019500395

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 心理的健康の維持・増進のための望ましい生活習慣についての疫学研究2007

    • Author(s)
      大平哲也, 他
    • Journal Title

      日本公衆衛生雑誌 54

      Pages: 226-235

    • NAID

      10019500395

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] "笑い"が将来の心身医学を変える!?2010

    • Author(s)
      大平哲也
    • Organizer
      第49回日本心身医学会九州地方会教育講演
    • Place of Presentation
      宮崎
    • Year and Date
      2010-02-07
    • Related Report
      2009 Final Research Report
  • [Presentation] "笑い"が将来の心身医学を変える!?2010

    • Author(s)
      大平哲也
    • Organizer
      第49回日本心身医学会九州地方会
    • Place of Presentation
      宮崎JAアズムホール
    • Year and Date
      2010-02-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] 睡眠呼吸障害と家庭血圧・心電図との関連についての疫学研究2009

    • Author(s)
      大平哲也
    • Organizer
      第68回日本公衆衛生学会総会
    • Place of Presentation
      奈良
    • Year and Date
      2009-10-21
    • Related Report
      2009 Final Research Report
  • [Presentation] 睡眠呼吸障害と家庭血圧・心電図との関連についての疫学研究2009

    • Author(s)
      大平哲也
    • Organizer
      第68回日本公衆衛生学会総会
    • Place of Presentation
      奈良県文化会館
    • Year and Date
      2009-10-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] 疲労とメタボリックシンドロームとの関連についての疫学研究2009

    • Author(s)
      大平哲也
    • Organizer
      第50回日本心身医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-06-06
    • Related Report
      2009 Final Research Report
  • [Presentation] 疲労とメタボリックシンドロームとの関連についての疫学研究2009

    • Author(s)
      大平哲也
    • Organizer
      第50回日本心身医学会総会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2009-06-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] 心理的因子と炎症との関連についての疫学研究2008

    • Author(s)
      大平哲也
    • Organizer
      第67回日本公衆衛生学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-11-05
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] Fatigue and metabolic syndrome among Japanese men and women2008

    • Author(s)
      Ohira T
    • Organizer
      International Conference on Fatigue Science
    • Place of Presentation
      沖縄
    • Year and Date
      2008-09-04
    • Related Report
      2009 Final Research Report
  • [Presentation] Fatigue and metabolic syndrome among Japanese men and women.2008

    • Author(s)
      Tetsuya Ohira, et al.
    • Organizer
      International Conference on Fatigue Science
    • Place of Presentation
      Nago, Okinawa
    • Year and Date
      2008-09-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 笑いの頻度と認知機能の関連についての疫学研究2008

    • Author(s)
      大平哲也
    • Organizer
      第15回日本笑い学会総会
    • Place of Presentation
      京都
    • Year and Date
      2008-07-13
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 肩こり、腰痛と身体心理的因子・生活習慣との関連についての疫学研究2008

    • Author(s)
      大平哲也
    • Organizer
      第49回日本心身医学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2008-06-12
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] 楽観的思考と循環器疾患危険因子との関連についての縦断研究2007

    • Author(s)
      大平哲也
    • Organizer
      第66回日本公衆衛生学会総会
    • Place of Presentation
      松山
    • Year and Date
      2007-10-25
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Presentation] 笑いの頻度とメタボリックシンドローム構成因子との関連についての疫学研究2007

    • Author(s)
      大平哲也
    • Organizer
      第48回日本心身医学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2007-05-25
    • Related Report
      2009 Final Research Report 2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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