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Hair has known the history of drugs abused

Research Project

Project/Area Number 19590672
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Legal medicine
Research InstitutionHiroshima University

Principal Investigator

NISHIDA Manami  Hiroshima University, 技術センター, 技術専門員 (60379914)

Co-Investigator(Kenkyū-buntansha) NAMERA Akira  広島大学, 大学院・医歯薬学総合研究科, 准教授 (30284186)
Project Period (FY) 2007 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords分析化学 / 乱用薬物 / 覚せい剤 / 毛髪 / 固相マイクロ抽出 / SPME / 社会医学 / 薬物中毒 / 合成麻薬 / 誘導体化
Research Abstract

The drug abuse is a serious problem in the world. Analysis of the drugs in human hair is very important to reveal the history of the drug abuse. So far, there has no report of a high sensitive determination method for determination of methamphetamine and amphetamine from a limited material such as a small piece of human hair. We developed a high sensitive and accurate method by using headspace solid phase microextraction. As a result, it was possible to determine the drugs from one piece of hair(1cm). The detection limit of this method was 20 and 50 pg for methamphetamine and amphetamine, respectively. The proposed method will be helpful to judge the period of the drug abuse without a pain for a patient.

Report

(6 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report   Self-evaluation Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (9 results)

All 2010 2007 Other

All Presentation (1 results) Book (7 results) Remarks (1 results)

  • [Presentation] 法医鑑定および保護観察対象者における薬物使用の検証2007

    • Author(s)
      西田まなみ
    • Organizer
      第55回質量分析総合討論会
    • Place of Presentation
      広島
    • Year and Date
      2007-05-15
    • Related Report
      2010 Final Research Report 2009 Self-evaluation Report
  • [Book] Techniques and Methods2010

    • Author(s)
      A.Nakamoto, M.Nishida, T.Saito, A.Namera
    • Publisher
      Nova Science Publishers Inc., Chromatography : Types
    • Related Report
      2010 Final Research Report
  • [Book] Techniques and Methods2010

    • Author(s)
      A.Namera, A.Nakamoto, T.Saito, M.Nishida
    • Publisher
      Nova Science Publishers Inc., Chromatography : Types
    • Related Report
      2010 Final Research Report
  • [Book] Chromatography : Types, Techniques and Methods2010

    • Author(s)
      A. Namera, A. Nakamoto, T. Saito, M. Nishida
    • Publisher
      Nova Science Publishers Inc.(in press)
    • Related Report
      2009 Self-evaluation Report
  • [Book] Chromatography : Types, Techniques and Methods2010

    • Author(s)
      A.Namera, A.Nakamoto, T.Saito, M.Nishida
    • Publisher
      Nova Science Publishers Inc.(in press)
    • Related Report
      2009 Annual Research Report
  • [Book] New Research on Methamphetamine Abuse.2007

    • Author(s)
      M.Nishida, M.Yashiki, A.Namera, K.Kimura
    • Publisher
      Nova Scientific Publishers Inc.
    • Related Report
      2010 Final Research Report
  • [Book] New Research on Methamphetamine Abuse2007

    • Author(s)
      M. Nishida, M. Yashiki, A. Namera, K. Kimura
    • Publisher
      Nova Scientific Publishers Inc.
    • Related Report
      2009 Self-evaluation Report
  • [Book] New Research on Methamphetamine Abuse2007

    • Author(s)
      Manami Nishida
    • Publisher
      Nova Science Publishers, Inc.
    • Related Report
      2007 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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