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A prospective study of etiological factors and long-term prognosis in adolescent Irritable Bowel Syndrome

Research Project

Project/Area Number 19590689
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General internal medicine (including Psychosomatic medicine)
Research InstitutionTohoku University

Principal Investigator

ENDO Yuka  東北大学, 病院, 助教 (00343046)

Co-Investigator(Kenkyū-buntansha) SHOJI Tomotaka  東北大学, 病院, 助教 (40360870)
木村 裕子  東北大学, 病院, 医員 (20400327)
福土 審  東北大学, 大学院・医学系研究科, 教授 (80199249)
Co-Investigator(Renkei-kenkyūsha) FUKUDO Shin  東北大学, 大学院・医学系研究科, 教授 (80199249)
Project Period (FY) 2007 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords思春期 / 過敏性腸症候群 / 発症因子 / 長期予後 / 自己効力感 / 失感情症 / クオリィティ・オブ・ライフ / トラウマ / 健康関連QOL / 健康関連OOL
Research Abstract

Almost 40%of the students showed changes of their bowel symptoms in three years and the prevalence of adolescent irritable bowel syndrome (IBS)was about 20%. The students with continuous IBS symptoms showed significantly lower self-efficacy and health-related quality of life (HR-QOL), more sleep disturbance, perceived stress, traumatic episodes and alexithymic tendency than the students without abdominal symptoms, however, the students with passing IBS symptoms didn' t have these features. The early onset and/or the sustainment of IBS symptoms may induce low self-efficacy and impaired HR-QOL.

Report

(6 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report   Self-evaluation Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (35 results)

All 2011 2010 2009 2008 2007

All Journal Article (13 results) (of which Peer Reviewed: 5 results) Presentation (21 results) Book (1 results)

  • [Journal Article] The features of adolescent irritable bowel syndrome in Japan2011

    • Author(s)
      Endo Y, Shoji T, Fukudo S, et al
    • Journal Title

      J Gastroenterol Hepatorol

      Volume: 26 Pages: 106-9

    • Related Report
      2010 Final Research Report
  • [Journal Article] The features of adolescent irritable bowel syndrome in Japan2011

    • Author(s)
      Y.Endo, T Shoji, S.Fukudo, et.al.
    • Journal Title

      Journal of Gastroenterology & Hepatology

      Volume: 26 Suppl 3 Pages: 106-109

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 治療(2)非薬物療法Q12生活習慣はどのように改善すればいいですか?2011

    • Author(s)
      遠藤由香
    • Journal Title

      IBS診療Q&A

      Pages: 76-80

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 心理ストレスによる身体反応思春期におけるストレスと過敏性腸症候群2010

    • Author(s)
      遠藤由香
    • Journal Title

      心身医学

      Volume: 50 Pages: 733-740

    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Journal Article] Effect of autogenic training on general improvement in patients with irritable bowel syndrome : a randomized controlled trial2010

    • Author(s)
      Endo Y, 他4名(4番目)
    • Journal Title

      Appl Psychophysiol Biofeedback

      Volume: 35 Pages: 189-98

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 機能性胃腸症(Functional Dyspepsia)の病態を巡る脳腸相関大脳誘発電位および飲水負荷試験からみたfunctional dyspepsiaの内臓知覚の検討2009

    • Author(s)
      庄司知隆、森下城、遠藤由香, 他
    • Journal Title

      心身医学

      Volume: 49 Pages: 777-782

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of serotonin transporter gene polymorphism on brain activation by colorectal distention2009

    • Author(s)
      福土審, 庄司知隆, 遠藤由香, et al.
    • Journal Title

      Neuroimage 47(3)

      Pages: 946-951

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 心身医学における研究と診療の最先端過敏性腸症候群における corticotropin-releasing hormone の役割2008

    • Author(s)
      福土審、庄司知隆、遠藤由香、他
    • Journal Title

      心身医学 48(7)

      Pages: 619-623

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 高校生における過敏性腸症候群の特徴2007

    • Author(s)
      遠藤由香, 福土審, 庄司知隆, 他7名
    • Journal Title

      心身医学 47

      Pages: 641-47

    • NAID

      110006317347

    • Related Report
      2009 Self-evaluation Report
  • [Journal Article] 中学三年生における過敏性腸症候群とストレス2007

    • Author(s)
      遠藤由香, 福土審, 庄司知隆, 他5名
    • Journal Title

      ストレス科学 21

      Pages: 208-216

    • Related Report
      2009 Self-evaluation Report
  • [Journal Article] 高校生こおける過敏性腸症候群の特徴2007

    • Author(s)
      遠藤由香、他
    • Journal Title

      心身医学 47巻

      Pages: 641-647

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of corticotropin-releasing hormone in irritable bowel syndrome and intestinal inflammation2007

    • Author(s)
      Shin Fukudo
    • Journal Title

      Journal of Gastroenterology 42spul.17

      Pages: 45-51

    • NAID

      10018539958

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 機能性消化管障害 Rome III基準と病態生理2007

    • Author(s)
      福土 審
    • Journal Title

      日本内科学会雑誌 96巻

      Pages: 1220-1227

    • NAID

      10019544159

    • Related Report
      2007 Annual Research Report
  • [Presentation] 中学生における腹部症状およびアレキシサイミア傾向と罹患時の親の気遣い度の検討2011

    • Author(s)
      遠藤由香
    • Organizer
      第16回日本心療内科学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-26
    • Related Report
      2010 Final Research Report
  • [Presentation] Children's perception of low parent solicitousness is correlated with alexithymic tendency and FBD symptoms in junior high school students in Japan2011

    • Author(s)
      Endo Y.
    • Organizer
      DDW 2011
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2011-05-10
    • Related Report
      2010 Final Research Report
  • [Presentation] The features of adolescent irritable bowel syndrome in Japan2010

    • Author(s)
      Endo Y.
    • Organizer
      The 1st Asian Pacific Topic Conference
    • Place of Presentation
      Tokyo
    • Year and Date
      2010-11-27
    • Related Report
      2010 Final Research Report
  • [Presentation] The features of adolescent irritable bowel syndrome in Japan2010

    • Author(s)
      Y Endo
    • Organizer
      Asian Pacific Topic Conference
    • Place of Presentation
      東京
    • Year and Date
      2010-11-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] 思春期過敏性腸症候群におけるアレキシサイミア傾向2010

    • Author(s)
      遠藤由香
    • Organizer
      第15回日本心療内科学会学術総会
    • Place of Presentation
      岡山
    • Year and Date
      2010-11-20
    • Related Report
      2010 Final Research Report
  • [Presentation] 思春期過敏性腸症候群におけるアレキシサイミア傾向2010

    • Author(s)
      遠藤由香
    • Organizer
      心療内科学会
    • Place of Presentation
      岡山
    • Year and Date
      2010-11-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Characteristics of adolescent Irritable Bowel Syndrome-population survey2010

    • Author(s)
      Endo Y.
    • Organizer
      The 18th United European Gastroenterology Week
    • Place of Presentation
      Balcerona, Spain
    • Year and Date
      2010-10-25
    • Related Report
      2010 Final Research Report
  • [Presentation] Characteristics of adolescent irritable bowel syndrome-population survey2010

    • Author(s)
      Y Endo
    • Organizer
      United European Gastroenterology Week
    • Place of Presentation
      バルセロナ、スペイン
    • Year and Date
      2010-10-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] 思春期における過敏性腸症候群の疫学的調査2010

    • Author(s)
      遠藤由香
    • Organizer
      消化器心身医学研究会
    • Place of Presentation
      新潟
    • Year and Date
      2010-04-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 心理的ストレスと身体反応-思春期におけるストレスと過敏性腸症候群2009

    • Author(s)
      遠藤由香
    • Organizer
      第1回日本心身医学5学会合同集会
    • Place of Presentation
      東京
    • Year and Date
      2009-06-07
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] 思春期におけるストレスと過敏性腸症候群2009

    • Author(s)
      遠藤由香
    • Organizer
      第1回日本心身医学5学会合同集会
    • Place of Presentation
      東京
    • Year and Date
      2009-06-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] 消化器愁訴と心身医療心身医療により社会復帰した Functional dyspepsia 難治症例2008

    • Author(s)
      庄司知隆、遠藤由香、他
    • Organizer
      第13回日本心療内科学会総会
    • Place of Presentation
      青森
    • Year and Date
      2008-11-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] 思春期過敏性腸症候群において自己効力感が症状および健康関連クオリティ・オブ・ライフに与える影響2008

    • Author(s)
      遠藤由香, 木村裕子, 福土審, 庄司知隆, 相模泰宏, 森下城, 町田知美, 町田貴胤, 金澤素, 本郷道夫
    • Organizer
      第49回日本心身医学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2008-06-12
    • Related Report
      2009 Self-evaluation Report 2008 Annual Research Report
  • [Presentation] 機能性胃腸症(Functional Dyspepsia)の病態を巡る脳腸相関 大脳誘発電位および飲水負荷試験からみた Functional dyspepsia の内臓知覚の検討2008

    • Author(s)
      庄司知隆、遠藤由香、他
    • Organizer
      第49回日本心身医学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2008-06-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] Low self-efficacy affects symptoms and quality of life in adolescents with irritable bowel syndrome2008

    • Author(s)
      Yuka Endo, Shin Fukudo, Tomotaka Shoji, Yasuhiro Sagami, Joe Morishita, Yuko Kimura, Tomomi Machida, Takatsugu Machida, Michio Hongo
    • Organizer
      AGA
    • Place of Presentation
      San Diego
    • Year and Date
      2008-05-19
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] Low self-efficacy affects symptoms and quality of life in adolescents with irritable bowel syndrome2008

    • Author(s)
      遠藤由香, et al.
    • Organizer
      The 109th Annual Meeting of American Gastroenterological Association
    • Place of Presentation
      サンディエゴ、USA
    • Year and Date
      2008-05-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] Rome IIIと機能性ディスペプシアの新たな展開大脳誘発電位および飲水負荷試験からみた Functional dyspepsia の内臓知覚の検討2008

    • Author(s)
      庄司知隆、他
    • Organizer
      第94回日本消化器病学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-05-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] 中学三年生における摂食行動とその影響2007

    • Author(s)
      遠藤由香、他
    • Organizer
      第12回日本心療内科学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-12-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] 高校生の健康関連QOLや自己効力感に腹部症状が与える影響2007

    • Author(s)
      遠藤由香、他
    • Organizer
      第48回日本心身医学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2007-05-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] The Characteristics of High School Students with Irritable Bowel Syndrome and Functional Bowel Disorder2007

    • Author(s)
      Yuka Endo, et. al.
    • Organizer
      The 108th Annual Meeting of American Gastroenterological Association
    • Place of Presentation
      USA
    • Year and Date
      2007-05-23
    • Related Report
      2007 Annual Research Report
  • [Presentation] 思春期過敏性腸症候群の特徴-性差の観点から-2007

    • Author(s)
      遠藤由香、他
    • Organizer
      第3回消化器病における性差医学・医療研究会
    • Place of Presentation
      青森
    • Year and Date
      2007-04-20
    • Related Report
      2007 Annual Research Report
  • [Book] (1)日本医事新報社、東京IBS診療Q & A治療(2)非薬物療法Q12生活習慣はどのように改善すればよいですか?2011

    • Author(s)
      遠藤由香
    • Publisher
      日本医事新報社、東京
    • Related Report
      2010 Final Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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