Identification of genetic factors of H.pylori difference between antral and body gastritis
Project/Area Number |
19590719
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Gastroenterology
|
Research Institution | University of Fukui |
Principal Investigator |
ITO Yoshiyuki University of Fukui, 医学部附属病院, 講師 (60313748)
|
Project Period (FY) |
2007 – 2008
|
Project Status |
Completed (Fiscal Year 2008)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
|
Keywords | ヘリコバクター・ピロリ / DNAサブトラクション法 / 前庭部胃炎 / 体部胃炎 / Helicobacter pylori / 胃炎 / 胃癌 |
Research Abstract |
DNAサブトラクション法を用いて疾患特異的および体部胃炎に特異的なヘリコバクターピロリ菌遺伝子の同定を試みた。その結果、十二指腸潰瘍株に有意に頻度が高い遺伝子断片を同定した。さらに以前に同定した日本株に特異的と考えられる膜蛋白について解析し、polyA を含みphase variableな遺伝子であった。
|
Report
(3 results)
Research Products
(6 results)
-
-
-
-
[Presentation] Genetic Diversity in dupA Region of H. pylori2009
Author(s)
Matsuda H., Ito Y, Ohno T, Matsunaga S, Ohtani M, Lee S, Nemoto T, Suto H, Yamazaki Y, Keida Y.
Organizer
XXnd International Workshop on Helicobacter and related bacteria in chronic digestive inflammation
Place of Presentation
Porto (Protugal)
Related Report
-
[Presentation] 日本において Helicobacter pylori dupA 遺伝子は疾患に特異的なマーカーとなりうるか2009
Author(s)
松田秀岳, 伊藤義幸, 高橋和人, 内藤達志, 森瀬涼子, 大野崇, 里見聡子, 大谷昌弘, 李相植, 根本朋幸, 須藤弘之, 山崎幸直
Organizer
第95回日本消化器病学会総会
Place of Presentation
札幌
Related Report
-
[Presentation] Helicobacter pylori vacA i-region genotype is associated with an increased risk of gastric cancer2008
Author(s)
Ito Y, Inagaki T. Yamakawa A, Satomi S, Matsuda H, Ohno T, Masaki R, Ohtani M, Lee S, Suto H, Yamazaki Y, Keida Y.
Organizer
vacuolating cytotoxin activity, and cagA status in Okinawa, Japan. Digestive Disease Week 2008
Place of Presentation
San Diego (USA)
Related Report